[HTML][HTML] PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms
F Briest, P Grabowski - Theranostics, 2014 - ncbi.nlm.nih.gov
Gastroenteropancreatic neuroendocrine neoplasms are heterogeneous in their clinical
behavior and require therapies specially tailored according to staging, grading, origin and
expression of peptide receptors. Despite extensive scientific efforts, the therapy options are …
behavior and require therapies specially tailored according to staging, grading, origin and
expression of peptide receptors. Despite extensive scientific efforts, the therapy options are …
[HTML][HTML] Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis
R Haataja, MK Karjalainen, A Luukkonen, K Teramo… - PLoS …, 2011 - journals.plos.org
Preterm birth is the major cause of neonatal death and serious morbidity. Most preterm births
are due to spontaneous onset of labor without a known cause or effective prevention. Both
maternal and fetal genomes influence the predisposition to spontaneous preterm birth …
are due to spontaneous onset of labor without a known cause or effective prevention. Both
maternal and fetal genomes influence the predisposition to spontaneous preterm birth …
GeneBase 1.1: a tool to summarize data from NCBI gene datasets and its application to an update of human gene statistics
A Piovesan, M Caracausi, F Antonaros, MC Pelleri… - Database, 2016 - academic.oup.com
Abstract We release GeneBase 1.1, a local tool with a graphical interface useful for parsing,
structuring and indexing data from the National Center for Biotechnology Information (NCBI)
Gene data bank. Compared to its predecessor GeneBase (1.0), GeneBase 1.1 now allows …
structuring and indexing data from the National Center for Biotechnology Information (NCBI)
Gene data bank. Compared to its predecessor GeneBase (1.0), GeneBase 1.1 now allows …
[HTML][HTML] Treatment of gastrointestinal neuroendocrine tumors with inhibitors of growth factor receptors and their signaling pathways: recent advances and future …
M Höpfner, D Schuppan, H Scherübl - World journal of …, 2008 - ncbi.nlm.nih.gov
The limited efficacy of conventional cytotoxic treatment regimes for advanced
gastrointestinal neuroendocrine cancers emphasizes the need for novel and more effective
medical treatment options. Recent findings on the specific biological features of this family of …
gastrointestinal neuroendocrine cancers emphasizes the need for novel and more effective
medical treatment options. Recent findings on the specific biological features of this family of …
[HTML][HTML] Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors
P Kuiper, LJAC Hawinkels… - World Journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To investigate the expression and potential prognostic role of vascular endothelial
growth factor (VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors (GEP-
NETs). METHODS: Microvessel density (MVD) in GEP-NETs was evaluated using endoglin …
growth factor (VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors (GEP-
NETs). METHODS: Microvessel density (MVD) in GEP-NETs was evaluated using endoglin …
Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank
A Piovesan, M Caracausi, M Ricci, P Strippoli… - DNA …, 2015 - academic.oup.com
We have developed GeneBase, a full parser of the National Center for Biotechnology
Information (NCBI) Gene database, which generates a fully structured local database with
an intuitive user-friendly graphic interface for personal computers. Features of all the …
Information (NCBI) Gene database, which generates a fully structured local database with
an intuitive user-friendly graphic interface for personal computers. Features of all the …
[HTML][HTML] Medical treatment for gastro-entero-pancreatic neuroendocrine tumours
R Berardi, F Morgese, M Torniai, A Savini… - World journal of …, 2016 - ncbi.nlm.nih.gov
Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs) represents a various
family of rare tumours. Surgery is the first choice in GEP-NENs patients with localized
disease whilst in the metastatic setting many other treatment options are available …
family of rare tumours. Surgery is the first choice in GEP-NENs patients with localized
disease whilst in the metastatic setting many other treatment options are available …
[HTML][HTML] Sequence," subtle" alternative splicing and expression of the CYYR1 (cysteine/tyrosine-rich 1) mRNA in human neuroendocrine tumors
L Vitale, F Frabetti, SA Huntsman, S Canaider… - BMC cancer, 2007 - Springer
CYYR1 is a recently identified gene located on human chromosome 21 whose product has
no similarity to any known protein and is of unknown function. Analysis of expressed
sequence tags (ESTs) have revealed high human CYYR1 expression in cells belonging to …
no similarity to any known protein and is of unknown function. Analysis of expressed
sequence tags (ESTs) have revealed high human CYYR1 expression in cells belonging to …
Identification and analysis of human RCAN3 (DSCR1L2) mRNA and protein isoforms
F Facchin, S Canaider, L Vitale, F Frabetti, C Griffoni… - Gene, 2008 - Elsevier
Human RCAN3 (Regulator of calcineurin 3; previously known as DSCR1L2, Down
syndrome critical region gene 1-like 2) is a five-exon gene mapped on chromosome 1 and
belongs to the human RCAN gene family which also includes RCAN1 and RCAN2. The …
syndrome critical region gene 1-like 2) is a five-exon gene mapped on chromosome 1 and
belongs to the human RCAN gene family which also includes RCAN1 and RCAN2. The …
[HTML][HTML] IGF-IEc expression is increased in secondary compared to primary foci in neuroendocrine neoplasms
KI Alexandraki, A Philippou, G Boutzios, I Theohari… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Different Insulin-like growth factor-I (IGF-I) mRNA transcripts are produced by alternative
splicing and particularly the IGF-IEc isoform has been implicated in the development and/or
progression of various types of cancer. In the present study, we examined the potential role …
splicing and particularly the IGF-IEc isoform has been implicated in the development and/or
progression of various types of cancer. In the present study, we examined the potential role …