Hongtao Yu
Hongtao Yu
Chair Professor of Cell Biology, School of Life Sciences, Westlake University
Verified email at
Cited by
Cited by
Structural basis for the binding of proline-rich peptides to SH3 domains
H Yu, JK Chen, S Feng, DC Dalgarno, AW Brauer, SL Schrelber
Cell 76 (5), 933-945, 1994
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions
S Feng, JK Chen, H Yu, JA Simon, SL Schreiber
Science 266 (5188), 1241-1247, 1994
Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins
S Lee, F Kopp, TC Chang, A Sataluri, B Chen, S Sivakumar, H Yu, Y Xie, ...
Cell 164 (1), 69-80, 2016
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
G Fang, H Yu, MW Kirschner
Genes & development 12 (12), 1871-1883, 1998
The spindle checkpoint, aneuploidy, and cancer
R Bharadwaj, H Yu
Oncogene 23 (11), 2016-2027, 2004
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
G Fang, H Yu, MW Kirschner
Molecular cell 2 (2), 163-171, 1998
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ...
Cancer cell 20 (4), 487-499, 2011
Human cohesin compacts DNA by loop extrusion
Y Kim, Z Shi, H Zhang, IJ Finkelstein, H Yu
Science 366 (6471), 1345-1349, 2019
Mutational inactivation of STAG2 causes aneuploidy in human cancer
DA Solomon, T Kim, LA Diaz-Martinez, J Fair, AG Elkahloun, BT Harris, ...
Science 333 (6045), 1039-1043, 2011
Mad2-independent inhibition of APC Cdc20 by the mitotic checkpoint protein BubR1
Z Tang, R Bharadwaj, B Li, H Yu
Developmental cell 1 (2), 227-237, 2001
Regulation of APC–Cdc20 by the spindle checkpoint
H Yu
Current opinion in cell biology 14 (6), 706-714, 2002
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
PR Potts, H Yu
Nature structural & molecular biology 14 (7), 581-590, 2007
Solution structure of the SH3 domain of Src and identification of its ligand-binding site
H Yu, MK Rosen, TB Shin, C Seidel-Dugan, JS Brugge, SL Schreiber
Science 258 (5088), 1665-1668, 1992
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
X Luo, Z Tang, J Rizo, H Yu
Molecular cell 9 (1), 59-71, 2002
Cdc20: a WD40 activator for a cell cycle degradation machine
H Yu
Molecular cell 27 (1), 3-16, 2007
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
Z Tang, H Shu, W Qi, NA Mahmood, MC Mumby, H Yu
Developmental cell 10 (5), 575-585, 2006
Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase
M Yang, CB Gocke, X Luo, D Borek, DR Tomchick, M Machius, ...
Molecular cell 23 (3), 377-387, 2006
The Mad2 spindle checkpoint protein has two distinct natively folded states
X Luo, Z Tang, G Xia, K Wassmann, T Matsumoto, J Rizo, H Yu
Nature structural & molecular biology 11 (4), 338-345, 2004
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint
Z Tang, H Shu, D Oncel, S Chen, H Yu
Molecular cell 16 (3), 387-397, 2004
Identification of a cullin homology region in a subunit of the anaphase-promoting complex
H Yu, JM Peters, RW King, AM Page, P Hieter, MW Kirschner
Science 279 (5354), 1219-1222, 1998
The system can't perform the operation now. Try again later.
Articles 1–20