| Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation ML Sos, HB Rode, S Heynck, M Peifer, F Fischer, S Klüter, VG Pawar, ... Cancer research 70 (3), 868-874, 2010 | 216 | 2010 |
| Structure-guided development of affinity probes for tyrosine kinases using chemical genetics JA Blair, D Rauh, C Kung, CH Yun, QW Fan, H Rode, C Zhang, MJ Eck, ... Nature Chemical Biology 3 (4), 229-238, 2007 | 215 | 2007 |
| Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc M Getlik, C Grütter, JR Simard, S Klüter, M Rabiller, HB Rode, ... Journal of medicinal chemistry 52 (13), 3915-3926, 2009 | 146 | 2009 |
| A new screening assay for allosteric inhibitors of cSrc JR Simard, S Klüter, C Grütter, M Getlik, M Rabiller, HB Rode, D Rauh Nature Chemical Biology 5 (6), 394-396, 2009 | 145 | 2009 |
| Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR A Michalczyk, S Klueter, HB Rode, JR Simard, C Gruetter, M Rabiller, ... Bioorganic & medicinal chemistry 16 (7), 3482-3488, 2008 | 102 | 2008 |
| Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor VG Pawar, ML Sos, HB Rode, M Rabiller, S Heynck, WAL Van Otterlo, ... Journal of medicinal chemistry 53 (7), 2892-2901, 2010 | 82 | 2010 |
| Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance S Klüter, JR Simard, HB Rode, C Grütter, V Pawar, HCA Raaijmakers, ... ChemBioChem 11 (18), 2557-2566, 2010 | 44 | 2010 |
| A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase A Koch, HB Rode, A Richters, D Rauh, S Hauf ACS chemical biology 7 (4), 723-731, 2012 | 28 | 2012 |
| Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling M Peifer, J Weiss, ML Sos, M Koker, S Heynck, C Netzer, S Fischer, ... PloS one 5 (1), e8919, 2010 | 25 | 2010 |
| On water direct arylation of imidazo [1, 2-a] pyridines with aryl halides S Kalari, DA Babar, UB Karale, VB Makane, HB Rode Tetrahedron Letters 58 (29), 2818-2821, 2017 | 23 | 2017 |
| Synthesis and biological evaluation of 2, 4, 5-trisubstituted thiazoles as antituberculosis agents effective against drug-resistant tuberculosis UB Karale, VS Krishna, EV Krishna, AS Choudhari, M Shukla, ... European Journal of Medicinal Chemistry 178, 315-328, 2019 | 22 | 2019 |
| Novel 1, 3, 4-oxadiazoles as antitubercular agents with limited activity against drug-resistant tuberculosis VB Makane, VS Krishna, EV Krishna, M Shukla, B Mahizhaveni, S Misra, ... Future Medicinal Chemistry 11 (6), 499-510, 2019 | 18 | 2019 |
| Strategies towards the synthesis of anti-tuberculosis drugs HB Rode, DM Lade, R Grée, PS Mainkar, S Chandrasekhar Organic & Biomolecular Chemistry 17 (22), 5428-5459, 2019 | 18 | 2019 |
| Crosslinked enzyme aggregates (CLEA) of phytase with soymilk proteins H Tirunagari, S Basetty, HB Rode, NW Fadnavis Journal of biotechnology 282, 67-69, 2018 | 16 | 2018 |
| Identification of new molecular entities (NMEs) as potential leads against tuberculosis from open source compound repository SS Kotapalli, SSA Nallam, L Nadella, T Banerjee, HB Rode, PS Mainkar, ... PLoS One 10 (12), e0144018, 2015 | 16 | 2015 |
| Synthesis and evaluation of α-aminoacyl amides as antitubercular agents effective on drug resistant tuberculosis VB Makane, VS Krishna, EV Krishna, M Shukla, B Mahizhaveni, S Misra, ... European Journal of Medicinal Chemistry 164, 665-677, 2019 | 13 | 2019 |
| Ligand-free Pd-catalysed decarboxylative arylation of imidazo [1, 2-a] pyridine-3-carboxylic acids with aryl bromides UB Karale, S Kalari, J Shivakumar, VB Makane, DA Babar, RP Thakare, ... RSC advances 6 (69), 65095-65104, 2016 | 13 | 2016 |
| Pseudosaccharin amine derivatives: synthesis and elastase inhibitory activity HB Rode, T Sprang, A Besch, J Loose, HH Otto Die Pharmazie-An International Journal of Pharmaceutical Sciences 60 (10 …, 2005 | 13 | 2005 |
| A Facile synthesis and antituberculosis properties of almazole D and its enantiomer DM Lade, VS Krishna, D Sriram, HB Rode ChemistrySelect 2 (3), 1250-1252, 2017 | 11 | 2017 |
| Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino) isoquinoline-4-carbonitriles as inhibitors of myosin light chain kinase and epidermal growth factor … HB Rode, ML Sos, C Grütter, S Heynck, JR Simard, D Rauh Bioorganic & medicinal chemistry 19 (1), 429-439, 2011 | 10 | 2011 |
Sidharth ChopraScientistVerified email at cdri.res.in
