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Brandon DeKosky
Brandon DeKosky
Verified email at mit.edu - Homepage
Title
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Cited by
Year
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
8082014
Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies
WS Lee, AK Wheatley, SJ Kent, BJ DeKosky
Nature microbiology 5 (10), 1185-1191, 2020
7462020
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
BJ DeKosky, GC Ippolito, RP Deschner, JJ Lavinder, Y Wine, ...
Nature biotechnology 31 (2), 166-169, 2013
5322013
In-depth determination and analysis of the human paired heavy-and light-chain antibody repertoire
BJ DeKosky, T Kojima, A Rodin, W Charab, GC Ippolito, AD Ellington, ...
Nature medicine 21 (1), 86-91, 2015
3992015
Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination
J Lee, DR Boutz, V Chromikova, MG Joyce, C Vollmers, K Leung, ...
Nature medicine 22 (12), 1456-1464, 2016
3242016
Identification and characterization of the constituent human serum antibodies elicited by vaccination
JJ Lavinder, Y Wine, C Giesecke, GC Ippolito, AP Horton, OI Lungu, ...
Proceedings of the National Academy of Sciences 111 (6), 2259-2264, 2014
2662014
Low CD21 expression defines a population of recent germinal center graduates primed for plasma cell differentiation
D Lau, LYL Lan, SF Andrews, C Henry, KT Rojas, KE Neu, M Huang, ...
Science immunology 2 (7), eaai8153, 2017
2482017
Induction of HIV neutralizing antibody lineages in mice with diverse precursor repertoires
M Tian, C Cheng, X Chen, H Duan, HL Cheng, M Dao, Z Sheng, M Kimble, ...
Cell 166 (6), 1471-1484. e18, 2016
2382016
Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires
BJ DeKosky, OI Lungu, D Park, EL Johnson, W Charab, C Chrysostomou, ...
Proceedings of the National Academy of Sciences 113 (19), E2636-E2645, 2016
2182016
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
J Gorman, C Soto, MM Yang, TM Davenport, M Guttman, RT Bailer, ...
Nature structural & molecular biology 23 (1), 81-90, 2016
1952016
The molecular mechanisms that underlie the immune biology of anti-drug antibody formation following treatment with monoclonal antibodies
A Vaisman-Mentesh, M Gutierrez-Gonzalez, BJ DeKosky, Y Wine
Frontiers in immunology 11, 1951, 2020
1812020
Hierarchically designed agarose and poly (ethylene glycol) interpenetrating network hydrogels for cartilage tissue engineering
BJ DeKosky, NH Dormer, GC Ingavle, CH Roatch, J Lomakin, ...
Tissue Engineering Part C: Methods 16 (6), 1533-1542, 2010
1792010
Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes
JR McDaniel, BJ DeKosky, H Tanno, AD Ellington, G Georgiou
Nature protocols 11 (3), 429-442, 2016
1682016
Functional interrogation and mining of natively paired human VH:VL antibody repertoires
B Wang, BJ DeKosky, MR Timm, J Lee, E Normandin, J Misasi, R Kong, ...
Nature biotechnology 36 (2), 152-155, 2018
1372018
Glycan masking focuses immune responses to the HIV-1 CD4-binding site and enhances elicitation of VRC01-class precursor antibodies
H Duan, X Chen, JC Boyington, C Cheng, Y Zhang, AJ Jafari, T Stephens, ...
Immunity 49 (2), 301-311. e5, 2018
1322018
Structure-based design with tag-based purification and in-process biotinylation enable streamlined development of SARS-CoV-2 spike molecular probes
T Zhou, IT Teng, AS Olia, G Cerutti, J Gorman, A Nazzari, W Shi, ...
Cell reports 33 (4), 2020
672020
Facile discovery of a diverse panel of anti-Ebola virus antibodies by immune repertoire mining
B Wang, CA Kluwe, OI Lungu, BJ DeKosky, SA Kerr, EL Johnson, ...
Scientific reports 5 (1), 13926, 2015
592015
Paired heavy-and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses
BB Banach, G Cerutti, AS Fahad, CH Shen, MO De Souza, PS Katsamba, ...
Cell Reports 37 (1), 2021
542021
High throughput sequencing of multiple transcripts
S Hunicke-Smith, B Dekosky, A Ellington, G Georgiou
US Patent 9,708,654, 2017
502017
Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses
M Mukhamedova, D Wrapp, CH Shen, MSA Gilman, TJ Ruckwardt, ...
Immunity 54 (4), 769-780. e6, 2021
492021
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