Early use of nitazoxanide in mild Covid-19 disease: randomised, placebo-controlled trial PRM Rocco, PL Silva, FF Cruz, MAC Melo-Junior, PF Tierno, MA Moura, ... European Respiratory Journal 58 (1), 2021 | 180 | 2021 |
Molecular and biochemical characterization of novel glucokinases from Trypanosoma cruzi and Leishmania spp. AJ Cáceres, W Quiñones, M Gualdrón, A Cordeiro, L Avilán, PAM Michels, ... Molecular and biochemical parasitology 156 (2), 235-245, 2007 | 58 | 2007 |
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites AT Cordeiro, OH Thiemann, PAM Michels Bioorganic & medicinal chemistry 17 (6), 2483-2489, 2009 | 55 | 2009 |
Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase PR Feliciano, AT Cordeiro, AJ Costa-Filho, MC Nonato Protein expression and purification 48 (1), 98-103, 2006 | 53 | 2006 |
Crystal structure of dihydroorotate dehydrogenase from Leishmania major AT Cordeiro, PR Feliciano, MP Pinheiro, MC Nonato Biochimie 94 (8), 1739-1748, 2012 | 51 | 2012 |
The crystal structure of glucose‐6‐phosphate isomerase from Leishmania mexicana reveals novel active site features AT Cordeiro, PAM Michels, LF Delboni, OH Thiemann European journal of biochemistry 271 (13), 2765-2772, 2004 | 51 | 2004 |
Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps AT Cordeiro, PHC Godoi, C Silva, RC Garratt, G Oliva, OH Thiemann Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1645 (2), 117-122, 2003 | 43 | 2003 |
Discovery of new uncompetitive inhibitors of glucose-6-phosphate dehydrogenase GF Mercaldi, AT Ranzani, AT Cordeiro Journal of biomolecular screening 19 (10), 1362-1371, 2014 | 36 | 2014 |
16-Bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in … AT Cordeiro, OH Thiemann Bioorganic & medicinal chemistry 18 (13), 4762-4768, 2010 | 35 | 2010 |
Glucose-6-phosphate dehydrogenase is the target for the trypanocidal action of human steroids S Gupta, AT Cordeiro, PAM Michels Molecular and biochemical parasitology 176 (2), 112-115, 2011 | 34 | 2011 |
Glucose-6-phosphate dehydrogenase of trypanosomatids: characterization, target validation, and drug discovery S Gupta, M Igoillo-Esteve, PAM Michels, AT Cordeiro Molecular biology international 2011, 2011 | 32 | 2011 |
The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes AT Cordeiro, AJ Cáceres, D Vertommen, JL Concepción, PAM Michels, ... Journal of molecular biology 372 (5), 1215-1226, 2007 | 30 | 2007 |
Selenocysteine incorporation in Kinetoplastid: Selenophosphate synthetase (SELD) from Leishmania major and Trypanosoma brucei SA Sculaccio, EM Rodrigues, AT Cordeiro, A Magalhaes, AL Braga, ... Molecular and biochemical parasitology 162 (2), 165-171, 2008 | 29 | 2008 |
The structure of a Trypanosoma cruzi glucose‐6‐phosphate dehydrogenase reveals differences from the mammalian enzyme GF Mercaldi, A Dawson, WN Hunter, AT Cordeiro FEBS letters 590 (16), 2776-2786, 2016 | 26 | 2016 |
Crystallization and preliminary X-ray diffraction analysis of Leishmania major dihydroorotate dehydrogenase AT Cordeiro, PR Feliciano, MC Nonato Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 23 | 2006 |
Synthesis and testing of novel alternative oxidase (AOX) inhibitors with antifungal activity against Moniliophthora perniciosa (Stahel), the causal agent of witches … MRO Barsottini, BA Pires, ML Vieira, JGC Pereira, PCS Costa, J Sanitá, ... Pest management science 75 (5), 1295-1303, 2019 | 20 | 2019 |
Structural role of the active‐site metal in the conformation of Trypanosoma brucei phosphoglycerate mutase GF Mercaldi, HM Pereira, AT Cordeiro, PAM Michels, OH Thiemann The FEBS Journal 279 (11), 2012-2021, 2012 | 20 | 2012 |
Identification of Specific Inhibitors of Trypanosoma cruzi Malic Enzyme Isoforms by Target-Based HTS AT Ranzani, C Nowicki, SR Wilkinson, AT Cordeiro SLAS DISCOVERY: Advancing Life Sciences R&D 22 (9), 1150-1161, 2017 | 18 | 2017 |
Mutations in the tetramer interface of human glucose‐6‐phosphate dehydrogenase reveals kinetic differences between oligomeric states AT Ranzani, AT Cordeiro FEBS letters 591 (9), 1278-1284, 2017 | 17 | 2017 |
SARITA-2 investigators. Early use of nitazoxanide in mild COVID-19 disease: randomised, placebo-controlled trial PRM Rocco, PL Silva, FF Cruz, MAC Melo-Junior, MMA Tierno PFGMM, ... Eur Respir J 58 (1), 2003725, 2021 | 16 | 2021 |