Alexander Goncearenco
Alexander Goncearenco
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Coupling between histone conformations and DNA geometry in nucleosomes on a microsecond timescale: atomistic insights into nucleosome functions
AK Shaytan, GA Armeev, A Goncearenco, VB Zhurkin, D Landsman, ...
Journal of molecular biology 428 (1), 221-237, 2016
A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency
I Lasry, YA Seo, H Ityel, N Shalva, B Pode-Shakked, F Glaser, B Berman, ...
Journal of Biological Chemistry 287 (35), 29348-29361, 2012
MutaBind estimates and interprets the effects of sequence variants on protein–protein interactions
M Li, FL Simonetti, A Goncearenco, AR Panchenko
Nucleic acids research 44 (W1), W494-W501, 2016
SPACER: server for predicting allosteric communication and effects of regulation
A Goncearenco, S Mitternacht, T Yong, B Eisenhaber, F Eisenhaber, ...
Nucleic acids research 41 (W1), W266-W272, 2013
Thermophilic adaptation of protein complexes inferred from proteomic homology modeling
BG Ma, A Goncearenco, IN Berezovsky
Structure 18 (7), 819-828, 2010
Exploring background mutational processes to decipher cancer genetic heterogeneity
A Goncearenco, SL Rager, M Li, QX Sang, IB Rogozin, AR Panchenko
Nucleic acids research 45 (W1), W514-W522, 2017
Protein function from its emergence to diversity in contemporary proteins
A Goncearenco, IN Berezovsky
Physical biology 12 (4), 045002, 2015
APOBEC mutagenesis and copy-number alterations are drivers of proteogenomic tumor evolution and heterogeneity in metastatic thoracic tumors
N Roper, S Gao, TK Maity, AR Banday, X Zhang, A Venugopalan, ...
Cell reports 26 (10), 2651-2666. e6, 2019
Finding driver mutations in cancer: Elucidating the role of background mutational processes
AL Brown, M Li, A Goncearenco, AR Panchenko
PLoS computational biology 15 (4), e1006981, 2019
Simple yet functional phosphate-loop proteins
MLR Romero, F Yang, YR Lin, A Toth-Petroczy, IN Berezovsky, ...
Proceedings of the National Academy of Sciences 115 (51), E11943-E11950, 2018
Mutational signatures and mutable motifs in cancer genomes
IB Rogozin, YI Pavlov, A Goncearenco, S De, AG Lada, E Poliakov, ...
Briefings in bioinformatics 19 (6), 1085-1101, 2018
Exploring protein-protein interactions as drug targets for anti-cancer therapy with in silico workflows
A Goncearenco, M Li, FL Simonetti, BA Shoemaker, AR Panchenko
Proteomics for Drug Discovery, 221-236, 2017
Prototypes of elementary functional loops unravel evolutionary connections between protein functions
A Goncearenco, IN Berezovsky
Bioinformatics 26 (18), i497-i503, 2010
Nucleotide binding database NBDB–a collection of sequence motifs with specific protein-ligand interactions
Z Zheng, A Goncearenco, IN Berezovsky
Nucleic acids research 44 (D1), D301-D307, 2016
Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins
A Goncearenco, BG Ma, IN Berezovsky
Nucleic acids research 42 (5), 2879-2892, 2014
DNA polymerase η mutational signatures are found in a variety of different types of cancer
IB Rogozin, A Goncearenco, AG Lada, S De, V Yurchenko, G Nudelman, ...
Cell Cycle 17 (3), 348-355, 2018
Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers
IB Rogozin, AG Lada, A Goncearenco, MR Green, S De, G Nudelman, ...
Scientific reports 6 (1), 1-9, 2016
Molecular recognition of nucleosomes by binding partners
S Kale, A Goncearenco, Y Markov, D Landsman, AR Panchenko
Current opinion in structural biology 56, 164-170, 2019
Computational approaches to prioritize cancer driver missense mutations
F Zhao, L Zheng, A Goncearenco, AR Panchenko, M Li
International journal of molecular sciences 19 (7), 2113, 2018
The fundamental tradeoff in genomes and proteomes of prokaryotes established by the genetic code, codon entropy, and physics of nucleic acids and proteins
A Goncearenco, IN Berezovsky
Biology direct 9 (1), 1-15, 2014
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Articles 1–20