| c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response JJ Woodward, AT Iavarone, DA Portnoy Science 328 (5986), 1703-1705, 2010 | 937 | 2010 |
| STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade J Fu, DB Kanne, M Leong, LH Glickman, SM McWhirter, E Lemmens, ... Science translational medicine 7 (283), 283ra52-283ra52, 2015 | 760 | 2015 |
| The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic … JD Sauer, K Sotelo-Troha, J Von Moltke, KM Monroe, CS Rae, ... Infection and immunity 79 (2), 688-694, 2011 | 642 | 2011 |
| Cutting edge: cGAS is required for lethal autoimmune disease in the Trex1-deficient mouse model of Aicardi–Goutières syndrome EE Gray, PM Treuting, JJ Woodward, DB Stetson The Journal of Immunology 195 (5), 1939-1943, 2015 | 381 | 2015 |
| SLC19A1 transports immunoreactive cyclic dinucleotides RD Luteijn, SA Zaver, BG Gowen, SK Wyman, NE Garelis, L Onia, ... Nature 573 (7774), 434-438, 2019 | 300 | 2019 |
| Replication-transcription conflicts generate R-loops that orchestrate bacterial stress survival and pathogenesis KS Lang, AN Hall, CN Merrikh, M Ragheb, H Tabakh, AJ Pollock, ... Cell 170 (4), 787-799. e18, 2017 | 259 | 2017 |
| The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function K Sureka, PH Choi, M Precit, M Delince, DA Pensinger, TAN Huynh, ... Cell 158 (6), 1389-1401, 2014 | 238 | 2014 |
| Cutting edge: antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase–DNA interaction J An, JJ Woodward, T Sasaki, M Minie, KB Elkon The Journal of Immunology 194 (9), 4089-4093, 2015 | 217 | 2015 |
| An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence TAN Huynh, S Luo, D Pensinger, JD Sauer, L Tong, JJ Woodward Proceedings of the National Academy of Sciences 112 (7), E747-E756, 2015 | 214 | 2015 |
| Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection CE Witte, AT Whiteley, TP Burke, JD Sauer, DA Portnoy, JJ Woodward MBio 4 (3), 10.1128/mbio. 00282-13, 2013 | 210 | 2013 |
| Expression of cyclic GMP‐AMP synthase in patients with systemic lupus erythematosus J An, L Durcan, RM Karr, TA Briggs, GI Rice, TH Teal, JJ Woodward, ... Arthritis & rheumatology 69 (4), 800-807, 2017 | 162 | 2017 |
| Antimalarial drugs as immune modulators: new mechanisms for old drugs J An, M Minie, T Sasaki, JJ Woodward, KB Elkon Annual review of medicine 68 (1), 317-330, 2017 | 137 | 2017 |
| c‐di‐AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation AT Whiteley, NE Garelis, BN Peterson, PH Choi, L Tong, JJ Woodward, ... Molecular microbiology 104 (2), 212-233, 2017 | 136 | 2017 |
| Sensing of bacterial cyclic dinucleotides by the oxidoreductase RECON promotes NF-κB activation and shapes a proinflammatory antibacterial state AP McFarland, S Luo, F Ahmed-Qadri, M Zuck, EF Thayer, YA Goo, ... Immunity 46 (3), 433-445, 2017 | 128 | 2017 |
| Development of a mariner-Based Transposon and Identification of Listeria monocytogenes Determinants, Including the Peptidyl-Prolyl Isomerase PrsA2, That … J Zemansky, BC Kline, JJ Woodward, JH Leber, H Marquis, DA Portnoy Journal of bacteriology 191 (12), 3950-3964, 2009 | 125 | 2009 |
| Listeria monocytogenes in Food-Processing Facilities, Food Contamination, and Human Listeriosis: The Brazilian Scenario AC Camargo, JJ Woodward, DR Call, LA Nero Foodborne Pathogens and Disease 14 (11), 623-636, 2017 | 123 | 2017 |
| Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity CE Witte, KA Archer, CS Rae, JD Sauer, JJ Woodward, DA Portnoy Advances in immunology 113, 135-156, 2012 | 121 | 2012 |
| Cyclic di‐AMP targets the cystathionine beta‐synthase domain of the osmolyte transporter OpuC TAN Huynh, PH Choi, K Sureka, HE Ledvina, J Campillo, L Tong, ... Molecular microbiology 102 (2), 233-243, 2016 | 111 | 2016 |
| Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm TAN Huynh, JJ Woodward Current opinion in microbiology 30, 22-29, 2016 | 110 | 2016 |
| Inhibition of Cyclic GMP‐AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1‐Deficient Mice J An, JJ Woodward, W Lai, M Minie, X Sun, L Tanaka, JM Snyder, ... Arthritis & Rheumatology 70 (11), 1807-1819, 2018 | 100 | 2018 |
