| A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, ... Cell Death & Differentiation 22 (5), 731-742, 2015 | 257 | 2015 |
| Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca2+ influx but only modestly influenced by mitochondria A Loreto, M Di Stefano, M Gering, L Conforti Cell reports 13 (11), 2539-2552, 2015 | 142 | 2015 |
| Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ... Neurobiology of disease 134, 104678, 2020 | 109 | 2020 |
| NMN deamidase delays Wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo M Di Stefano*, A Loreto*(equal contribution), G Orsomando, V Mori, ... Current Biology 27 (6), 784-794, 2017 | 104 | 2017 |
| Advances in applying computer-aided drug design for neurodegenerative diseases MM Salman, Z Al-Obaidi, P Kitchen, A Loreto, RM Bill, R Wade-Martins International journal of molecular sciences 22 (9), 4688, 2021 | 94 | 2021 |
| Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ... Acta neuropathologica communications 7, 1-16, 2019 | 70 | 2019 |
| SARM1 is a multi-functional NAD (P) ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites C Angeletti, A Amici, J Gilley, A Loreto, AG Trapanotto, C Antoniou, ... Iscience 25 (2), 2022 | 65* | 2022 |
| Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity PD Mabbitt, A Loreto, MA Déry, AJ Fletcher, M Stanley, KC Pao, NT Wood, ... Nature chemical biology 16 (11), 1227-1236, 2020 | 55 | 2020 |
| Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... Elife 10, e72823, 2021 | 42* | 2021 |
| Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain HC Feldman, E Merlini, C Guijas, KE DeMeester, E Njomen, EM Kozina, ... Proceedings of the National Academy of Sciences 119 (35), e2208457119, 2022 | 40 | 2022 |
| Mitochondrial dysfunction as a trigger of programmed axon death E Merlini, MP Coleman, A Loreto Trends in Neurosciences 45 (1), 53-63, 2022 | 38 | 2022 |
| Novel HDAC6 inhibitors increase tubulin acetylation and rescue axonal transport of mitochondria in a model of Charcot–Marie–Tooth type 2F R Adalbert, A Kaieda, C Antoniou, A Loreto, X Yang, J Gilley, T Hoshino, ... ACS chemical neuroscience 11 (3), 258-267, 2019 | 29 | 2019 |
| NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy F Rossi, PC Geiszler, W Meng, MR Barron, M Prior, A Herd-Smith, ... Behavioural brain research 339, 140-152, 2018 | 25 | 2018 |
| Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes G Di Pasquale, I Dicembrini, L Raimondi, C Pagano, JM Egan, A Cozzi, ... PLoS One 7 (7), e40074, 2012 | 24 | 2012 |
| Loss of highwire protects against the deleterious effects of traumatic brain injury in Drosophila melanogaster CS Hill, J Sreedharan, A Loreto, DK Menon, MP Coleman Frontiers in Neurology 11, 525926, 2020 | 15 | 2020 |
| The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila AL Rosell, M Paglione, J Gilley, M Kocia, G Perillo, M Gasparrini, ... Elife 11, e80245, 2022 | 14 | 2022 |
| NMN: The NAD precursor at the intersection between axon degeneration and anti-ageing therapies A Loreto, C Antoniou, E Merlini, J Gilley, MP Coleman Neuroscience Research 197, 18-24, 2023 | 10 | 2023 |
| Axon degeneration assays in superior cervical ganglion explant cultures A Loreto, J Gilley Axon Degeneration: Methods and Protocols, 15-24, 2020 | 9 | 2020 |
| SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice SV Fazal, C Mutschler, CZ Chen, M Turmaine, CY Chen, YP Hsueh, ... Frontiers in Cellular Neuroscience 17, 1158388, 2023 | 5 | 2023 |
| Cultured dissociated primary dorsal root ganglion neurons from adult horses enable study of axonal transport R Adalbert, S Cahalan, EL Hopkins, A Almuhanna, A Loreto, E Pór, ... Journal of anatomy 241 (5), 1211-1218, 2022 | 5 | 2022 |
Elisa MerliniPhD student, University of CambridgeVerified email at cam.ac.uk
