More than smell—COVID-19 is associated with severe impairment of smell, taste, and chemesthesis V Parma, K Ohla, MG Veldhuizen, MY Niv, CE Kelly, AJ Bakke, ... Chemical Senses 45 (7), 609-622, 2020 | 105 | 2020 |
Allostery in its many disguises: from theory to applications SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ... Structure 27 (4), 566-578, 2019 | 96 | 2019 |
Recurrent inactivating RASA2 mutations in melanoma R Arafeh, N Qutob, R Emmanuel, A Keren-Paz, J Madore, A Elkahloun, ... Nature genetics 47 (12), 1408-1410, 2015 | 77 | 2015 |
COVID-19 and the chemical senses: supporting players take center stage KW Cooper, DH Brann, MC Farruggia, S Bhutani, R Pellegrino, ... Neuron, 2020 | 67 | 2020 |
Comparing Class A GPCRs to bitter taste receptors: Structural motifs, ligand interactions and agonist-to-antagonist ratios A Di Pizio, A Levit, M Slutzki, M Behrens, R Karaman, MY Niv Methods in cell biology 132, 401-427, 2016 | 49 | 2016 |
BitterDB: taste ligands and receptors database in 2019 A Dagan-Wiener, A Di Pizio, I Nissim, MS Bahia, N Dubovski, E Margulis, ... Nucleic acids research 47 (D1), D1179-D1185, 2019 | 48 | 2019 |
Promiscuity and selectivity of bitter molecules and their receptors A Di Pizio, MY Niv Bioorganic & medicinal chemistry 23 (14), 4082-4091, 2015 | 48 | 2015 |
Coronaviruses and the Chemical Senses: Past, Present, and Future R Pellegrino, KW Cooper, A Di Pizio, PV Joseph, S Bhutani, V Parma Chemical Senses, 2020 | 41 | 2020 |
Computational studies of smell and taste receptors A Di Pizio, MY Niv Israel Journal of Chemistry 54 (8‐9), 1205-1218, 2014 | 35 | 2014 |
Probing the binding pocket of the broadly tuned human bitter taste receptor TAS2R14 by chemical modification of cognate agonists R Karaman, S Nowak, A Di Pizio, H Kitaneh, A Abu‐Jaish, W Meyerhof, ... Chemical biology & drug design 88 (1), 66-75, 2016 | 33 | 2016 |
Bitter and sweet tasting molecules: It's complicated A Di Pizio, YB Shoshan-Galeczki, JE Hayes, MY Niv Neuroscience letters 700, 56-63, 2019 | 27 | 2019 |
Beyond the flavour: the potential druggability of chemosensory G protein-coupled receptors A Di Pizio, M Behrens, D Krautwurst International journal of molecular sciences 20 (6), 1402, 2019 | 25 | 2019 |
Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14 S Nowak, A Di Pizio, A Levit, MY Niv, W Meyerhof, M Behrens Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (10), 2162-2173, 2018 | 22 | 2018 |
Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case A Di Pizio, LM Kruetzfeldt, S Cheled-Shoval, W Meyerhof, M Behrens, ... Scientific reports 7 (1), 1-11, 2017 | 21 | 2017 |
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activity M Tauro, A Laghezza, F Loiodice, L Piemontese, A Caradonna, D Capelli, ... Journal of enzyme inhibition and medicinal chemistry 31 (sup4), 25-37, 2016 | 18 | 2016 |
Probing the S1′ Site for the Identification of Non‐Zinc‐Binding MMP‐2 Inhibitors A Di Pizio, A Laghezza, P Tortorella, M Agamennone ChemMedChem 8 (9), 1475-1482, 2013 | 17* | 2013 |
Sweet, umami and bitter taste receptors: State of the art of in silico molecular modeling approaches G Spaggiari, A Di Pizio, P Cozzini Trends in Food Science & Technology 96, 21-29, 2020 | 16 | 2020 |
Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms RC Gerkin, K Ohla, MG Veldhuizen, PV Joseph, CE Kelly, AJ Bakke, ... Chemical senses 46, 2021 | 13* | 2021 |
Rational design of agonists for bitter taste receptor TAS2R14: From modeling to bench and back A Di Pizio, R Brox, S Löber, D Weikert, M Behrens, P Gmeiner, MY Niv Cellular and Molecular Life Sciences 77 (3), 531-542, 2020 | 13 | 2020 |
Non-zinc-binding inhibitors of MMP-13: GRID-based approaches to rationalize the binding process A Di Pizio, M Agamennone, P Tortorella Current topics in medicinal chemistry 16 (4), 449-459, 2016 | 12 | 2016 |