| Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 587 | 2021 |
| Primaquine revisited six decades after its discovery N Vale, R Moreira, P Gomes European journal of medicinal chemistry 44 (3), 937-953, 2009 | 425 | 2009 |
| Synthetic organic chemistry driven by artificial intelligence AF de Almeida, R Moreira, T Rodrigues Nature Reviews Chemistry 3 (10), 589-604, 2019 | 235 | 2019 |
| Indoloquinolines as scaffolds for drug discovery J Lavrado, R Moreira, A Paulo Current medicinal chemistry 17 (22), 2348-2370, 2010 | 204 | 2010 |
| Michael acceptors as cysteine protease inhibitors. MM Santos, R Moreira Mini reviews in medicinal chemistry 7 (10), 1040-1050, 2007 | 189 | 2007 |
| An overview of drug resistance in protozoal diseases R Capela, R Moreira, F Lopes International journal of molecular sciences 20 (22), 5748, 2019 | 154 | 2019 |
| Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho [2, 3-d] isoxazole-4, 9-diones MMM Santos, N Faria, J Iley, SJ Coles, MB Hursthouse, ML Martins, ... Bioorganic & medicinal chemistry letters 20 (1), 193-195, 2010 | 137 | 2010 |
| Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug FP da Cruz, C Martin, K Buchholz, MJ Lafuente-Monasterio, T Rodrigues, ... Journal of Infectious Diseases 205 (8), 1278-1286, 2012 | 136 | 2012 |
| Drug discovery in tuberculosis. New drug targets and antimycobacterial agents A Campaniço, R Moreira, F Lopes European journal of medicinal chemistry 150, 525-545, 2018 | 123 | 2018 |
| Design of Modular G‐quadruplex Ligands AR Duarte, E Cadoni, AS Ressurreição, R Moreira, A Paulo ChemMedChem 13 (9), 869-893, 2018 | 115 | 2018 |
| Targeting COPD: advances on low‐molecular‐weight inhibitors of human neutrophil elastase SD Lucas, E Costa, RC Guedes, R Moreira Medicinal research reviews 33 (S1), E73-E101, 2013 | 112 | 2013 |
| Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials MJ Araújo, J Bom, R Capela, C Casimiro, P Chambel, P Gomes, J Iley, ... Journal of medicinal chemistry 48 (3), 888-892, 2005 | 100 | 2005 |
| Targeting the liver stage of malaria parasites: a yet unmet goal T Rodrigues, M Prudêncio, R Moreira, MM Mota, F Lopes Journal of medicinal chemistry 55 (3), 995-1012, 2012 | 97 | 2012 |
| Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins KK Hanson, AS Ressurreição, K Buchholz, M Prudêncio, ... Proceedings of the National Academy of Sciences 110 (30), E2838-E2847, 2013 | 95 | 2013 |
| Metabolism of primaquine by liver homogenate fractions: evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to … L Constantino, P Paixao, R Moreira, MJ Portela, VE Do Rosario, J Iley Experimental and Toxicologic Pathology 51 (4-5), 299-303, 1999 | 94 | 1999 |
| KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines J Lavrado, H Brito, PM Borralho, SA Ohnmacht, NS Kim, C Leitão, S Pisco, ... Scientific reports 5 (1), 9696, 2015 | 91 | 2015 |
| Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity MP Carrasco, AS Newton, L Gonçalves, A Góis, M Machado, J Gut, ... European journal of medicinal chemistry 80, 523-534, 2014 | 86 | 2014 |
| Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy R Capela, GG Cabal, PJ Rosenthal, J Gut, MM Mota, R Moreira, F Lopes, ... Antimicrobial agents and chemotherapy 55 (10), 4698-4706, 2011 | 85 | 2011 |
| Synthesis of imidazolidin-4-one and 1H-imidazo [2, 1-a] isoindole-2, 5 (3H, 9bH)-dione derivatives of primaquine: scope and limitations P Gomes, MJ Araújo, M Rodrigues, N Vale, Z Azevedo, J Iley, P Chambel, ... Tetrahedron 60 (26), 5551-5562, 2004 | 82 | 2004 |
| Constrained damping layer treatments: Finite element modeling R Moreira, JD Rodrigues Journal of Vibration and Control 10 (4), 575-595, 2004 | 80 | 2004 |
