Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ... Science 379 (6632), eabo3627, 2022 | 70 | 2022 |
Wheat germ agglutinin as a potential therapeutic agent for leukemia B Ryva, K Zhang, A Asthana, D Wong, Y Vicioso, R Parameswaran Frontiers in oncology 9, 100, 2019 | 49 | 2019 |
Hexosamine biosynthetic pathway inhibition leads to AML cell differentiation and cell death A Asthana, P Ramakrishnan, Y Vicioso, K Zhang, R Parameswaran Molecular cancer therapeutics 17 (10), 2226-2237, 2018 | 45 | 2018 |
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers DP Wong, NK Roy, K Zhang, A Anukanth, A Asthana, NJ Shirkey-Son, ... Nature communications 13 (1), 217, 2022 | 33 | 2022 |
Structural aspects and chaperone activity of human HspB3: role of the “C-terminal extension” A Asthana, B Raman, T Ramakrishna, CM Rao Cell biochemistry and biophysics 64, 61-72, 2012 | 29 | 2012 |
Hsp27 suppresses the Cu2+-induced amyloidogenicity, redox activity, and cytotoxicity of α-synuclein by metal ion stripping A Asthana, M Bollapalli, R Tangirala, R Bakthisaran, CM Rao Free Radical Biology and Medicine 72, 176-190, 2014 | 22 | 2014 |
Specificity and mechanism of coronavirus, rotavirus, and mammalian two-histidine phosphoesterases that antagonize antiviral innate immunity A Asthana, C Gaughan, B Dong, SR Weiss, RH Silverman MBio 12 (4), 10.1128/mbio. 01781-21, 2021 | 20 | 2021 |
Transport of non-transferrin bound iron to the brain: implications for Alzheimer’s disease AK Tripathi, S Karmakar, A Asthana, A Ashok, V Desai, S Baksi, N Singh Journal of Alzheimer's Disease 58 (4), 1109-1119, 2017 | 18 | 2017 |
Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders A Asthana, S Baksi, A Ashok, S Karmakar, N Mammadova, R Kokemuller, ... Scientific reports 7 (1), 9600, 2017 | 17 | 2017 |
Glycosylation differentially modulates membranolytic and chaperone-like activities of PDC-109, the major protein of bovine seminal plasma BP Singh, RS Sankhala, A Asthana, T Ramakrishna, CM Rao, MJ Swamy Biochemical and biophysical research communications 511 (1), 28-34, 2019 | 13 | 2019 |
The prion-ZIP connection: From cousins to partners in iron uptake N Singh, A Asthana, S Baksi, V Desai, S Haldar, S Hari, AK Tripathi Prion 9 (6), 420-428, 2015 | 12 | 2015 |
Combination therapy for treating advanced drug-resistant acute lymphoblastic leukemia Y Vicioso, H Gram, R Beck, A Asthana, K Zhang, DP Wong, J Letterio, ... Cancer immunology research 7 (7), 1106-1119, 2019 | 11 | 2019 |
Conserved core tryptophans of FnII domains are crucial for the membranolytic and chaperone‐like activities of bovine seminal plasma protein PDC‐109 BP Singh, A Asthana, A Basu, R Tangirala, C Mohan Rao, MJ Swamy FEBS letters 594 (3), 509-518, 2020 | 9 | 2020 |
Inhibition of O-GlcNAcylation decreases the cytotoxic function of natural killer cells D Feinberg, P Ramakrishnan, DP Wong, A Asthana, R Parameswaran Frontiers in Immunology 13, 841299, 2022 | 8 | 2022 |
Identification of small molecule inhibitors of RNase L by fragment-based drug discovery J Tang, B Dong, M Liu, S Liu, X Niu, C Gaughan, A Asthana, H Zhou, Z Xu, ... Journal of medicinal chemistry 65 (2), 1445-1457, 2021 | 7 | 2021 |
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling CJ Otter, N Bracci, NA Parenti, C Ye, A Asthana, EK Blomqvist, LH Tan, ... Proceedings of the National Academy of Sciences 121 (15), e2320194121, 2024 | 2 | 2024 |
Analogs of the catechol derivative dynasore inhibit HIV-1 ribonuclease H, SARS-CoV-2 nsp14 exoribonuclease, and virus replication A Asthana, A Corona, WJ Shin, MJ Kwak, C Gaughan, E Tramontano, ... Viruses 15 (7), 1539, 2023 | 2 | 2023 |
Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L J Xi, G Snieckute, JF Martínez, FSW Arendrup, A Asthana, C Gaughan, ... Cell Reports 43 (4), 2024 | 1 | 2024 |
Ligand Based CAR T-Cell Targeting BAFF Receptors Asa Novel Therapy for B Cell Malignancies R Parameswaran, D Wong, K Zhang, A Asthana, M de Lima, PF Caimi Blood 136, 31-32, 2020 | 1 | 2020 |
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling (preprint) CJ Otter, N Bracci, NA Parenti, C Ye, TL Hui, A Asthana, JJ Pfannenstiel, ... | | 2023 |