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Abhishek Asthana
Abhishek Asthana
Cleveland Clinic-Lerner Research Institute
Verified email at ccf.org
Title
Cited by
Cited by
Year
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ...
Science 379 (6632), eabo3627, 2022
702022
Wheat germ agglutinin as a potential therapeutic agent for leukemia
B Ryva, K Zhang, A Asthana, D Wong, Y Vicioso, R Parameswaran
Frontiers in oncology 9, 100, 2019
492019
Hexosamine biosynthetic pathway inhibition leads to AML cell differentiation and cell death
A Asthana, P Ramakrishnan, Y Vicioso, K Zhang, R Parameswaran
Molecular cancer therapeutics 17 (10), 2226-2237, 2018
452018
A BAFF ligand-based CAR-T cell targeting three receptors and multiple B cell cancers
DP Wong, NK Roy, K Zhang, A Anukanth, A Asthana, NJ Shirkey-Son, ...
Nature communications 13 (1), 217, 2022
332022
Structural aspects and chaperone activity of human HspB3: role of the “C-terminal extension”
A Asthana, B Raman, T Ramakrishna, CM Rao
Cell biochemistry and biophysics 64, 61-72, 2012
292012
Hsp27 suppresses the Cu2+-induced amyloidogenicity, redox activity, and cytotoxicity of α-synuclein by metal ion stripping
A Asthana, M Bollapalli, R Tangirala, R Bakthisaran, CM Rao
Free Radical Biology and Medicine 72, 176-190, 2014
222014
Specificity and mechanism of coronavirus, rotavirus, and mammalian two-histidine phosphoesterases that antagonize antiviral innate immunity
A Asthana, C Gaughan, B Dong, SR Weiss, RH Silverman
MBio 12 (4), 10.1128/mbio. 01781-21, 2021
202021
Transport of non-transferrin bound iron to the brain: implications for Alzheimer’s disease
AK Tripathi, S Karmakar, A Asthana, A Ashok, V Desai, S Baksi, N Singh
Journal of Alzheimer's Disease 58 (4), 1109-1119, 2017
182017
Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders
A Asthana, S Baksi, A Ashok, S Karmakar, N Mammadova, R Kokemuller, ...
Scientific reports 7 (1), 9600, 2017
172017
Glycosylation differentially modulates membranolytic and chaperone-like activities of PDC-109, the major protein of bovine seminal plasma
BP Singh, RS Sankhala, A Asthana, T Ramakrishna, CM Rao, MJ Swamy
Biochemical and biophysical research communications 511 (1), 28-34, 2019
132019
The prion-ZIP connection: From cousins to partners in iron uptake
N Singh, A Asthana, S Baksi, V Desai, S Haldar, S Hari, AK Tripathi
Prion 9 (6), 420-428, 2015
122015
Combination therapy for treating advanced drug-resistant acute lymphoblastic leukemia
Y Vicioso, H Gram, R Beck, A Asthana, K Zhang, DP Wong, J Letterio, ...
Cancer immunology research 7 (7), 1106-1119, 2019
112019
Conserved core tryptophans of FnII domains are crucial for the membranolytic and chaperone‐like activities of bovine seminal plasma protein PDC‐109
BP Singh, A Asthana, A Basu, R Tangirala, C Mohan Rao, MJ Swamy
FEBS letters 594 (3), 509-518, 2020
92020
Inhibition of O-GlcNAcylation decreases the cytotoxic function of natural killer cells
D Feinberg, P Ramakrishnan, DP Wong, A Asthana, R Parameswaran
Frontiers in Immunology 13, 841299, 2022
82022
Identification of small molecule inhibitors of RNase L by fragment-based drug discovery
J Tang, B Dong, M Liu, S Liu, X Niu, C Gaughan, A Asthana, H Zhou, Z Xu, ...
Journal of medicinal chemistry 65 (2), 1445-1457, 2021
72021
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling
CJ Otter, N Bracci, NA Parenti, C Ye, A Asthana, EK Blomqvist, LH Tan, ...
Proceedings of the National Academy of Sciences 121 (15), e2320194121, 2024
22024
Analogs of the catechol derivative dynasore inhibit HIV-1 ribonuclease H, SARS-CoV-2 nsp14 exoribonuclease, and virus replication
A Asthana, A Corona, WJ Shin, MJ Kwak, C Gaughan, E Tramontano, ...
Viruses 15 (7), 1539, 2023
22023
Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
J Xi, G Snieckute, JF Martínez, FSW Arendrup, A Asthana, C Gaughan, ...
Cell Reports 43 (4), 2024
12024
Ligand Based CAR T-Cell Targeting BAFF Receptors Asa Novel Therapy for B Cell Malignancies
R Parameswaran, D Wong, K Zhang, A Asthana, M de Lima, PF Caimi
Blood 136, 31-32, 2020
12020
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling (preprint)
CJ Otter, N Bracci, NA Parenti, C Ye, TL Hui, A Asthana, JJ Pfannenstiel, ...
2023
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