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Harvey F. Chin
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Actin network architecture can determine myosin motor activity
AC Reymann, R Boujemaa-Paterski, JL Martiel, C Guérin, W Cao, ...
Science 336 (6086), 1310-1314, 2012
3412012
The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes
Y Cai, HF Chin, D Lazarova, S Menon, C Fu, H Cai, A Sclafani, ...
Cell 133 (7), 1202-1213, 2008
2092008
Mechanism of cytokinetic contractile ring constriction in fission yeast
MR Stachowiak, C Laplante, HF Chin, B Guirao, E Karatekin, TD Pollard, ...
Developmental cell 29 (5), 547-561, 2014
1432014
TLR4 (toll-like receptor 4)-dependent signaling drives extracellular catabolism of LDL (low-density lipoprotein) aggregates
RK Singh, AS Haka, A Asmal, VC Barbosa-Lorenzi, I Grosheva, HF Chin, ...
Arteriosclerosis, thrombosis, and vascular biology 40 (1), 86-102, 2020
582020
A myosin V inhibitor based on privileged chemical scaffolds
K Islam, HF Chin, AO Olivares, LP Saunders, EM De La Cruz, TM Kapoor
Angewandte Chemie 122 (45), 8662-8666, 2010
472010
STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC
J Garbarino, M Pan, HF Chin, FW Lund, FR Maxfield, JL Breslow
Journal of lipid research 53 (12), 2716-2725, 2012
452012
Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex
E Prochniewicz, HF Chin, A Henn, DE Hannemann, AO Olivares, ...
Journal of molecular biology 396 (3), 501-509, 2010
452010
Monocyte-derived dendritic cells upregulate extracellular catabolism of aggregated low-density lipoprotein on maturation, leading to foam cell formation
AS Haka, RK Singh, I Grosheva, H Hoffner, E Capetillo-Zarate, HF Chin, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (10), 2092-2103, 2015
362015
Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor
HF Chin, Y Cai, S Menon, S Ferro-Novick, KM Reinisch, M Enrique
Journal of molecular biology 389 (2), 275-288, 2009
332009
Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin
K Shiroguchi, HF Chin, DE Hannemann, E Muneyuki, EM De La Cruz, ...
PLoS biology 9 (4), e1001031, 2011
322011
Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism [S]
RK Singh, AS Haka, A Brumfield, I Grosheva, P Bhardwaj, HF Chin, ...
Journal of lipid research 58 (10), 1977-1987, 2017
222017
Actin filament dynamics in the actomyosin VI complex is regulated allosterically by calcium–calmodulin light chain
E Prochniewicz, A Pierre, BR McCullough, HF Chin, W Cao, LP Saunders, ...
Journal of molecular biology 413 (3), 584-592, 2011
102011
Myosins generate contractile force and maintain organization in the cytokinetic contractile ring
Z McDargh, S Wang, HF Chin, S Thiyagarajan, E Karatekin, TD Pollard, ...
bioRxiv, 2021.05. 02.442363, 2021
92021
An integrated outsourcing practice of nonclinical LC–MS bioanalysis and toxicokinetics at Novartis small molecule drug development
W Li, J Glick, P Hatsis, Y Fu, H Chin, P Moench, J Flarakos
Bioanalysis 13 (12), 1001-1010, 2021
12021
Two isoforms of myosin-II cooperate to organize the fission yeast cytokinetic ring for maximal tension production
S Wang, H Chin, S Thiyagarajan, E Karatekin, TD Pollard, ...
Biophysical Journal 114 (3), 654a, 2018
12018
TLR4 Signaling Regulates Lysosome Exocytosis to a Novel Extracellular Compartment
RK Singh, AS Haka, HF Chin, I Grosheva, FR Maxfield
Faseb Journal 27, 2013
12013
Potent Rifampicin derivatives can clear MRSA infections at single low doses when concomitantly dosed with Vancomycin
T Nittoli, AB Zumsteg, A Bandyopadhyay, S Federici, A Coppi, ...
The Journal of Antibiotics 77 (1), 57-65, 2024
2024
TLR4-dependent signaling drives extracellular catabolism of low-density lipoprotein aggregates
RK Singh, AS Haka, A Asmal, VC Barbosa-Lorenzi, I Grosheva, HF Chin, ...
bioRxiv, 610162, 2019
2019
Macrophage catabolism of aggregated lipoproteins using a novel extracellular compartment regulates lipid accumulation during atherosclerosis
RK Singh, AS Haka, VC Barbosa-Lorenzi, A Asmal, F Lund, Y Xiong, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 37 (suppl_1), A570-A570, 2017
2017
Fission Yeast Contractile Ring Tension Increases∼ 2-Fold Throughout Constriction and Regulates Septum Closure but does not Set the Constriction Rate
S Thiyagarajan, H Chin, E Karatekin, TD Pollard, B O'Shaughnessy
Biophysical Journal 112 (3), 30a, 2017
2017
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