| Optimization of the indenone ring of indenoisoquinoline topoisomerase I inhibitors A Morrell, M Placzek, S Parmley, B Grella, S Antony, Y Pommier, ... Journal of medicinal chemistry 50 (18), 4388-4404, 2007 | 137 | 2007 |
| 11 C [double bond, length as m-dash] O bonds made easily for positron emission tomography radiopharmaceuticals BH Rotstein, SH Liang, MS Placzek, JM Hooker, AD Gee, F Dollé, ... Chemical Society Reviews 45 (17), 4708-4726, 2016 | 100 | 2016 |
| Nitrated indenoisoquinolines as topoisomerase I inhibitors: a systematic study and optimization A Morrell, M Placzek, S Parmley, S Antony, TS Dexheimer, Y Pommier, ... Journal of medicinal chemistry 50 (18), 4419-4430, 2007 | 89 | 2007 |
| Site-selective 18 F fluorination of unactivated C–H bonds mediated by a manganese porphyrin W Liu, X Huang, MS Placzek, SW Krska, P McQuade, JM Hooker, ... Chemical Science 9 (5), 1168-1172, 2018 | 80 | 2018 |
| Investigation of the lactam side chain length necessary for optimal indenoisoquinoline topoisomerase I inhibition and cytotoxicity in human cancer cell cultures A Morrell, MS Placzek, JD Steffen, S Antony, K Agama, Y Pommier, ... Journal of medicinal chemistry 50 (9), 2040-2048, 2007 | 80 | 2007 |
| Virtually Instantaneous, Room-Temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes HG Lee, PJ Milner, MS Placzek, SL Buchwald, JM Hooker Journal of the American Chemical Society 137 (2), 648-651, 2015 | 72 | 2015 |
| Virtually Instantaneous, Room-Temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes HG Lee, PJ Milner, MS Placzek, SL Buchwald, JM Hooker Journal of the American Chemical Society 137 (2), 648-651, 2015 | 72 | 2015 |
| [11 C] Cyanation of arylboronic acids in aqueous solutions L Ma, MS Placzek, JM Hooker, N Vasdev, SH Liang Chemical communications 53 (49), 6597-6600, 2017 | 45 | 2017 |
| Microwave-accelerated fluorodenitrations and nitrodehalogenations: expeditious routes to labeled PET ligands and fluoropharmaceuticals P LaBeaume, M Placzek, M Daniels, I Kendrick, P Ng, M McNeel, ... Tetrahedron Letters 51 (14), 1906-1909, 2010 | 43 | 2010 |
| Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging K Fabio, C Guillon, CJ Lacey, S Lu, ND Heindel, CF Ferris, M Placzek, ... Bioorganic & medicinal chemistry 20 (3), 1337-1345, 2012 | 38 | 2012 |
| Neuroimmune signatures in chronic low back pain subtypes Z Alshelh, L Brusaferri, A Saha, E Morrissey, P Knight, M Kim, Y Zhang, ... Brain 145 (3), 1098-1110, 2022 | 35 | 2022 |
| A novel radiotracer for imaging monoacylglycerol lipase in the brain using positron emission tomography C Wang, MS Placzek, GC Van de Bittner, FA Schroeder, JM Hooker ACS Chemical Neuroscience 7 (4), 484-489, 2016 | 35 | 2016 |
| Development of a fluorinated class-I HDAC radiotracer reveals key chemical determinants of brain penetrance MG Strebl, C Wang, FA Schroeder, MS Placzek, HY Wey, ... ACS chemical neuroscience 7 (5), 528-533, 2016 | 29 | 2016 |
| In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates M Schoenberger, FA Schroeder, MS Placzek, RL Carter, BR Rosen, ... ACS chemical neuroscience 9 (2), 298-305, 2018 | 24 | 2018 |
| PET neurochemical imaging modes MS Placzek, W Zhao, HY Wey, TM Morin, JM Hooker Seminars in nuclear medicine 46 (1), 20-27, 2016 | 24 | 2016 |
| Discrepancies in kappa opioid agonist binding revealed through PET imaging MS Placzek, FA Schroeder, T Che, HY Wey, R Neelamegam, C Wang, ... ACS Chemical Neuroscience 10 (1), 384-395, 2018 | 22 | 2018 |
| Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET) Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, ... Acta Pharmaceutica Sinica B 9 (6), 1204-1215, 2019 | 19 | 2019 |
| Immediate and persistent effects of salvinorin A on the kappa opioid receptor in rodents, monitored in vivo with PET MS Placzek, GC Van de Bittner, HY Wey, SE Lukas, JM Hooker Neuropsychopharmacology 40 (13), 2865-2872, 2015 | 17 | 2015 |
| Fluoroalkynylations of aryl halides under continuous-flow homogeneous catalysis MS Placzek, JM Chmielecki, C Houghton, A Calder, C Wiles, GB Jones Journal of Flow Chemistry 3 (2), 46-50, 2013 | 15 | 2013 |
| Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2 HS Krishnan, V Bernard-Gauthier, MS Placzek, K Dahl, V Narayanaswami, ... Molecular Pharmaceutics 15 (2), 695-702, 2018 | 14 | 2018 |
Jacob HookerHarvard Medical SchoolVerified email at nmr.mgh.harvard.edu
