Novel arylimidamides for treatment of visceral leishmaniasis MZ Wang, X Zhu, A Srivastava, Q Liu, JM Sweat, T Pandharkar, ... Antimicrobial Agents and Chemotherapy 54 (6), 2507-2516, 2010 | 101 | 2010 |
Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif M Munde, MA Ismail, R Arafa, P Peixoto, CJ Collar, Y Liu, L Hu, ... Journal of the American Chemical Society 129 (44), 13732-13743, 2007 | 81 | 2007 |
Structure-dependent inhibition of the ETS-family transcription factor PU. 1 by novel heterocyclic diamidines M Munde, S Wang, A Kumar, CE Stephens, AA Farahat, DW Boykin, ... Nucleic acids research 42 (2), 1379-1390, 2013 | 76 | 2013 |
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines R Nhili, P Peixoto, S Depauw, S Flajollet, X Dezitter, MM Munde, ... Nucleic acids research 41 (1), 125-138, 2013 | 75 | 2013 |
Induced fit conformational changes of a “reversed amidine” heterocycle: optimized interactions in a DNA minor groove complex M Munde, M Lee, S Neidle, R Arafa, DW Boykin, Y Liu, C Bailly, ... Journal of the American Chemical Society 129 (17), 5688-5698, 2007 | 57 | 2007 |
Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site EA Lewis, M Munde, S Wang, M Rettig, V Le, V Machha, WD Wilson Nucleic acids research 39 (22), 9649-9658, 2011 | 47 | 2011 |
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site M Munde, A Kumar, R Nhili, S Depauw, MH David-Cordonnier, MA Ismail, ... Journal of molecular biology 402 (5), 847-864, 2010 | 45 | 2010 |
Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents RK Arafa, MA Ismail, M Munde, WD Wilson, T Wenzler, R Brun, ... European journal of medicinal chemistry 43 (12), 2901-2908, 2008 | 41 | 2008 |
Mechanistic heterogeneity in site recognition by the structurally homologous DNA-binding domains of the ETS family transcription factors Ets-1 and PU. 1 S Wang, MH Linde, M Munde, VD Carvalho, WD Wilson, GMK Poon Journal of Biological Chemistry 289 (31), 21605-21616, 2014 | 38 | 2014 |
Azaterphenyl diamidines as antileishmanial agents L Hu, RK Arafa, MA Ismail, T Wenzler, R Brun, M Munde, WD Wilson, ... Bioorganic & medicinal chemistry letters 18 (1), 247-251, 2008 | 37 | 2008 |
The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA A Daliry, MQ Pires, CF Silva, RS Pacheco, M Munde, CE Stephens, ... Antimicrobial agents and chemotherapy 55 (10), 4765-4773, 2011 | 35 | 2011 |
Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-binding domain of the ETS family transcription factor PU. 1: a binding … M Munde, GMK Poon, WD Wilson Journal of molecular biology 425 (10), 1655-1669, 2013 | 34 | 2013 |
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum L Hu, RK Arafa, MA Ismail, A Patel, M Munde, WD Wilson, T Wenzler, ... Bioorganic & medicinal chemistry 17 (18), 6651-6658, 2009 | 34 | 2009 |
A comprehensive biophysical analysis of the effect of DNA binding drugs on protamine-induced DNA condensation S Gupta, N Tiwari, M Munde Scientific reports 9 (1), 5891, 2019 | 33 | 2019 |
Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity … X Zhu, Q Liu, S Yang, T Parman, CE Green, JC Mirsalis, ... Antimicrobial agents and chemotherapy 56 (7), 3690-3699, 2012 | 32 | 2012 |
Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures RA Hunt, M Munde, A Kumar, MA Ismail, AA Farahat, RK Arafa, M Say, ... Nucleic acids research 39 (10), 4265-4274, 2011 | 31 | 2011 |
Targeting the ICB2 site of the topoisomerase IIα promoter with a formamido-pyrrole–imidazole–pyrrole H-pin polyamide A Franks, C Tronrud, K Kiakos, J Kluza, M Munde, T Brown, H Mackay, ... Bioorganic & medicinal chemistry 18 (15), 5553-5561, 2010 | 30 | 2010 |
Minor groove to major groove, an unusual DNA sequence-dependent change in bend directionality by a distamycin dimer S Wang, M Munde, S Wang, WD Wilson Biochemistry 50 (35), 7674-7683, 2011 | 29 | 2011 |
Leishmania donovani parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase R Manhas, S Tandon, SS Sen, N Tiwari, M Munde, R Madhubala Antimicrobial Agents and Chemotherapy 62 (9), 10.1128/aac. 00079-18, 2018 | 28 | 2018 |
Impact of Module-X2 and Carbohydrate Binding Module-3 on the catalytic activity of associated glycoside hydrolases towards plant biomass. YSS Pasari N, Adlakha N, Gupta M, Bashir Z, Rajacharya GH, Verma G, Munde M ... Sci Rep. 7 (1), 2017 | 28 | 2017 |