| International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma KF Chung, SE Wenzel, JL Brozek, A Bush, M Castro, PJ Sterk, IM Adcock, ... European respiratory journal 43 (2), 343-373, 2014 | 4227 | 2014 |
| Eosinophilic inflammation in asthma J Bousquet, P Chanez, JY Lacoste, G Barnéon, N Ghavanian, I Enander, ... New England Journal of Medicine 323 (15), 1033-1039, 1990 | 3296 | 1990 |
| Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial ID Pavord, S Korn, P Howarth, ER Bleecker, R Buhl, ON Keene, H Ortega, ... The Lancet 380 (9842), 651-659, 2012 | 2424 | 2012 |
| Mepolizumab treatment in patients with severe eosinophilic asthma HG Ortega, MC Liu, ID Pavord, GG Brusselle, JM FitzGerald, A Chetta, ... New England journal of medicine 371 (13), 1198-1207, 2014 | 2296 | 2014 |
| An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical … HK Reddel, DR Taylor, ED Bateman, LP Boulet, HA Boushey, WW Busse, ... American journal of respiratory and critical care medicine 180 (1), 59-99, 2009 | 2135 | 2009 |
| Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised … ER Bleecker, JM FitzGerald, P Chanez, A Papi, SF Weinstein, P Barker, ... The Lancet 388 (10056), 2115-2127, 2016 | 1322 | 2016 |
| Induction of nitric oxide synthase in asthma Q Hamid, DR Springall, JM Polak, V Riveros-Moreno, P Chanez, ... The Lancet 342 (8886-8887), 1510-1513, 1993 | 1064 | 1993 |
| Withdrawal of inhaled glucocorticoids and exacerbations of COPD H Magnussen, B Disse, R Rodriguez-Roisin, A Kirsten, H Watz, K Tetzlaff, ... New England Journal of Medicine 371 (14), 1285-1294, 2014 | 784 | 2014 |
| Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis AM Vignola, P Chanez, G Chiappara, A Merendino, E Pace, A Rizzo, ... American journal of respiratory and critical care medicine 156 (2), 591-599, 1997 | 771 | 1997 |
| A new perspective on concepts of asthma severity and control DR Taylor, ED Bateman, LP Boulet, HA Boushey, WW Busse, TB Casale, ... European Respiratory Journal 32 (3), 545-554, 2008 | 728 | 2008 |
| Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells MJ Schuijs, MA Willart, K Vergote, D Gras, K Deswarte, MJ Ege, ... Science 349 (6252), 1106-1110, 2015 | 631 | 2015 |
| Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis AM Vignola, L Riccobono, A Mirabella, M Profita, P Chanez, V Bellia, ... American journal of respiratory and critical care medicine 158 (6), 1945-1950, 1998 | 586 | 1998 |
| Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort DE Shaw, AR Sousa, SJ Fowler, LJ Fleming, G Roberts, J Corfield, ... European Respiratory Journal 46 (5), 1308-1321, 2015 | 573 | 2015 |
| Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease JY Lacoste, J Bousquet, P Chanez, T Van Vyve, J Simony-Lafontaine, ... Journal of allergy and clinical immunology 92 (4), 537-548, 1993 | 572 | 1993 |
| A randomized, double-blind, placebo-controlled study of tumor necrosis factor-α blockade in severe persistent asthma SE Wenzel, PJ Barnes, ER Bleecker, J Bousquet, W Busse, SE Dahlén, ... American journal of respiratory and critical care medicine 179 (7), 549-558, 2009 | 559 | 2009 |
| Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel … KF Chung, P Godard, E Adelroth, J Ayres, N Barnes, P Barnes, E Bel, ... European Respiratory Journal 13 (5), 1198-1208, 1999 | 548 | 1999 |
| Management of severe asthma: a European respiratory society/American thoracic society guideline F Holguin, JC Cardet, KF Chung, S Diver, DS Ferreira, A Fitzpatrick, ... European respiratory journal 55 (1), 2020 | 504 | 2020 |
| Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial H Watz, K Tetzlaff, EFM Wouters, A Kirsten, H Magnussen, ... The lancet Respiratory medicine 4 (5), 390-398, 2016 | 502 | 2016 |
| Rhinosinusitis in severe asthma M Bresciani, L Paradis, A Des Roches, H Vernhet, I Vachier, P Godard, ... Journal of allergy and clinical immunology 107 (1), 73-80, 2001 | 486 | 2001 |
| Sputum induction PL Paggiaro, P Chanez, O Holz, PW Ind, R Djukanovic, P Maestrelli, ... European Respiratory Journal 20, 3s-8s, 2002 | 481 | 2002 |
