| Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation MFM Sciacca, SA Kotler, JR Brender, J Chen, D Lee, A Ramamoorthy Biophysical journal 103 (4), 702-710, 2012 | 391 | 2012 |
| Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP MFM Sciacca, C Tempra, F Scollo, D Milardi, C La Rosa Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1625-1638, 2018 | 126 | 2018 |
| Phosphatidylethanolamine enhances amyloid fiber dependent membrane fragmentation MFM Sciacca, JR Brender, DK Lee, A Ramamoorthy Biophysical Journal 102 (3), 488a, 2012 | 123 | 2012 |
| Lipid-chaperone hypothesis: A common molecular mechanism of membrane disruption by intrinsically disordered proteins MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ... ACS chemical neuroscience 11 (24), 4336-4350, 2020 | 119 | 2020 |
| Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP MFM Sciacca, D Milardi, GML Messina, G Marletta, JR Brender, ... Biophysical Journal 104 (1), 173-184, 2013 | 119 | 2013 |
| Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes? AJ McHenry, MFM Sciacca, JR Brender, A Ramamoorthy Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 3019-3024, 2012 | 103 | 2012 |
| Probing the Sources of the Apparent Irreproducibility of Amyloid Formation: Drastic Changes in Kinetics and a Switch in Mechanism due to Micelle-Like Oligomer Formation at … AR Jeffrey R Brender, Janarthanan Krishnamoorthy, Michele Francesco Maria ... The Journal of Physical Chemistry B, 2015 | 99 | 2015 |
| The role of cholesterol in driving IAPP-membrane interactions MFM Sciacca, F Lolicato, G Di Mauro, D Milardi, L D’Urso, C Satriano, ... Biophysical journal 111 (1), 140-151, 2016 | 90 | 2016 |
| Inhibition of Aβ amyloid growth and toxicity by silybins: The crucial role of stereochemistry MFM Sciacca, V Romanucci, A Zarrelli, I Monaco, F Lolicato, N Spinella, ... ACS chemical neuroscience 8 (8), 1767-1778, 2017 | 82 | 2017 |
| Phospholipids critical micellar concentrations trigger different mechanisms of intrinsically disordered proteins interaction with model membranes F Scollo, C Tempra, F Lolicato, MFM Sciacca, A Raudino, D Milardi, ... The journal of physical chemistry letters 9 (17), 5125-5129, 2018 | 77 | 2018 |
| Lipid composition-dependent membrane fragmentation and pore-forming mechanisms of membrane disruption by pexiganan (MSI-78) DK Lee, JR Brender, MFM Sciacca, J Krishnamoorthy, C Yu, ... Biochemistry 52 (19), 3254-3263, 2013 | 77 | 2013 |
| Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer’s disease and other tauopathies F Florenzano, C Veronica, G Ciasca, MT Ciotti, A Pittaluga, G Olivero, ... Oncotarget 8 (39), 64745, 2017 | 56 | 2017 |
| The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH D Milardi, MFM Sciacca, M Pappalardo, DM Grasso, C La Rosa European Biophysics Journal 40, 1-12, 2011 | 55 | 2011 |
| Self-assembling pathway of HiApp fibrils within lipid bilayers S Scalisi, MFM Sciacca, G Zhavnerko, DM Grasso, G Marletta, C La Rosa ChemBioChem 11 (13), 1856-1859, 2010 | 45 | 2010 |
| Calcium-activated membrane interaction of the islet amyloid polypeptide: Implications in the pathogenesis of type II diabetes mellitus MFM Sciacca, M Pappalardo, D Milardi, DM Grasso, C La Rosa Archives of biochemistry and biophysics 477 (2), 291-298, 2008 | 45 | 2008 |
| Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels J Zhao, R Hu, MFM Sciacca, JR Brender, H Chen, A Ramamoorthy, ... Physical Chemistry Chemical Physics 16 (6), 2368-2377, 2014 | 40 | 2014 |
| Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: the role of copper (II) ions, pH, and membrane mimicking environments G Di Natale, G Pappalardo, D Milardi, MFM Sciacca, F Attanasio, ... The Journal of Physical Chemistry B 114 (43), 13830-13838, 2010 | 40 | 2010 |
| A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage MFM Sciacca, R Chillemi, S Sciuto, V Greco, C Messineo, SA Kotler, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1793-1802, 2018 | 39 | 2018 |
| The active role of Ca 2+ ions in Aβ-mediated membrane damage MFM Sciacca, I Monaco, C La Rosa, D Milardi Chemical communications 54 (29), 3629-3631, 2018 | 31 | 2018 |
| Trehalose conjugates of silybin as prodrugs for targeting toxic Aβ aggregates S García-Viñuales, R Ahmed, MFM Sciacca, V Lanza, ML Giuffrida, ... ACS Chemical Neuroscience 11 (17), 2566-2576, 2020 | 23 | 2020 |
