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Tom H.M. Ottenhoff, MD, PhD
Tom H.M. Ottenhoff, MD, PhD
Professor in Immunology of Mycobacterial Infectious Diseases at LUMC
Verified email at lumc.nl - Homepage
Title
Cited by
Cited by
Year
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco) bacteria
FAW Verreck, T de Boer, DML Langenberg, MA Hoeve, M Kramer, ...
Proceedings of the National Academy of Sciences 101 (13), 4560-4565, 2004
12642004
Innate Immunity to Mycobacterium tuberculosis
R van Crevel, THM Ottenhoff, JWM Van der Meer
Clinical microbiology reviews 15 (2), 294-309, 2002
10672002
Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients
R Jong, F Altare, IA Haagen, DG Elferink, T Boer, ...
Science 280 (5368), 1435-1438, 1998
10241998
A blood RNA signature for tuberculosis disease risk: a prospective cohort study
DE Zak, A Penn-Nicholson, TJ Scriba, E Thompson, S Suliman, LM Amon, ...
The Lancet 387 (10035), 2312-2322, 2016
7462016
Expression of FOXP3 mRNA is not confined to CD4+ CD25+ T regulatory cells in humans
ME Morgan, JHM van Bilsen, AM Bakker, B Heemskerk, MW Schilham, ...
Human immunology 66 (1), 13-20, 2005
6462005
Vaccines against tuberculosis: where are we and where do we need to go?
THM Ottenhoff, SHE Kaufmann
PLoS pathogens 8 (5), e1002607, 2012
5912012
The effect of type 2 diabetes mellitus on the presentation and treatment response of pulmonary tuberculosis
B Alisjahbana, E Sahiratmadja, EJ Nelwan, AM Purwa, Y Ahmad, ...
Clinical infectious diseases 45 (4), 428-435, 2007
5662007
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ-and CD40L-mediated …
FAW Verreck, T de Boer, DML Langenberg, L van der Zanden, ...
Journal of leukocyte biology 79 (2), 285-293, 2006
5462006
Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells
MCAA Tan, AM Mommaas, JW Drijfhout, R Jordens, JJM Onderwater, ...
European journal of immunology 27 (9), 2426-2435, 1997
4701997
Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria
THM Ottenhoff, D Kumararatne, JL Casanova
Immunology today 19 (11), 491-494, 1998
4671998
NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis
G Ferwerda, SE Girardin, BJ Kullberg, L Le Bourhis, DJ De Jong, ...
PLoS pathogens 1 (3), e34, 2005
4472005
Is there a future for TNF promoter polymorphisms?
JP Bayley, THM Ottenhoff, CL Verweij
Genes & Immunity 5 (5), 315-329, 2004
3962004
Diagnosis of childhood tuberculosis and host RNA expression in Africa
ST Anderson, M Kaforou, AJ Brent, VJ Wright, CM Banwell, G Chagaluka, ...
New England Journal of Medicine 370 (18), 1712-1723, 2014
3832014
Multifunctional CD4+ T cells correlate with active Mycobacterium tuberculosis infection
N Caccamo, G Guggino, SA Joosten, G Gelsomino, P Di Carlo, L Titone, ...
European journal of immunology 40 (8), 2211-2220, 2010
3832010
Detection of tuberculosis in HIV-infected and-uninfected African adults using whole blood RNA expression signatures: a case-control study
M Kaforou, VJ Wright, T Oni, N French, ST Anderson, N Bangani, ...
PLoS medicine 10 (10), e1001538, 2013
3702013
Selection of a human T helper type 1-like T cell subset by mycobacteria.
JB Haanen, R de Waal Malefijt, PC Res, EM Kraakman, TH Ottenhoff, ...
The Journal of experimental medicine 174 (3), 583-592, 1991
3701991
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
C Kuijl, NDL Savage, M Marsman, AW Tuin, L Janssen, DA Egan, ...
Nature 450 (7170), 725-730, 2007
3682007
Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis
EMS Leyten, MY Lin, KLMC Franken, AH Friggen, C Prins, ...
Microbes and infection 8 (8), 2052-2060, 2006
3332006
Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis
S Davila, ML Hibberd, R Hari Dass, HEE Wong, E Sahiratmadja, ...
PLoS genetics 4 (10), e1000218, 2008
3312008
Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae
THM Ottenhoff, FAW Verreck, EGR Lichtenauer-Kaligis, MA Hoeve, ...
Nature genetics 32 (1), 97-105, 2002
3302002
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Articles 1–20