Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast RT Youker, P Walsh, T Beilharz, T Lithgow, JL Brodsky Molecular biology of the cell 15 (11), 4787-4797, 2004 | 190 | 2004 |
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA … KM Atkins, L Thomas, RT Youker, MJ Harriff, F Pissani, H You, G Thomas Journal of biological chemistry 283 (17), 11772-11784, 2008 | 122 | 2008 |
At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis RT Youker, U Shinde, R Day, G Thomas Biochemical Journal 421 (1), 1-15, 2009 | 83 | 2009 |
Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis JE Aslan, H You, DM Williamson, J Endig, RT Youker, L Thomas, H Shu, ... Molecular cell 34 (4), 497-509, 2009 | 77 | 2009 |
Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis H Zhang, BZ Schmidt, F Sun, SB Condliffe, MB Butterworth, RT Youker, ... Journal of biological chemistry 281 (16), 11312-11321, 2006 | 65 | 2006 |
FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability DM Hutt, DM Roth, MA Chalfant, RT Youker, J Matteson, JL Brodsky, ... Journal of Biological Chemistry 287 (26), 21914-21925, 2012 | 45 | 2012 |
Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9–dependent mechanism D Mo, SA Costa, G Ihrke, RT Youker, N Pastor-Soler, RP Hughey, ... Molecular Biology of the Cell 23 (18), 3636-3646, 2012 | 40 | 2012 |
Localization of the BiP molecular chaperone with respect to endoplasmic reticulum foci containing the cystic fibrosis transmembrane conductance regulator in yeast ML Sullivan, RT Youker, SC Watkins, JL Brodsky Journal of Histochemistry & Cytochemistry 51 (4), 545-548, 2003 | 36 | 2003 |
Measuring protein dynamics in live cells: protocols and practical considerations for fluorescence fluctuation microscopy RT Youker, H Teng Journal of biomedical optics 19 (9), 090801-090801, 2014 | 33 | 2014 |
Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization RT Youker, JR Bruns, SA Costa, Y Rbaibi, F Lanni, OB Kashlan, H Teng, ... Molecular biology of the cell 24 (12), 1996-2007, 2013 | 32 | 2013 |
Multiple biosynthetic trafficking routes for apically secreted proteins in MDCK cells PE Mattila, RT Youker, D Mo, JR Bruns, KO Cresawn, RP Hughey, G Ihrke, ... Traffic 13 (3), 433-442, 2012 | 29 | 2012 |
Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease A Labilloy, RT Youker, JR Bruns, I Kukic, K Kiselyov, W Halfter, ... Molecular genetics and metabolism 111 (2), 184-192, 2014 | 23 | 2014 |
Teaching biochemistry and molecular biology with virtual reality—lesson creation and student response HA Coan, G Goehle, RT Youker Journal of Teaching and Learning 14 (1), 71–92-71–92, 2020 | 14 | 2020 |
Regulation of Hsp70 function: hsp40 co-chaperones and nucleotide exchange factors RT Youker, JL Brodsky Cell stress proteins, 209-227, 2007 | 8 | 2007 |
Disease-relevant mutations alter amino acid co-evolution networks in the second nucleotide binding domain of CFTR G Ivey, RT Youker Plos one 15 (1), e0227668, 2020 | 6 | 2020 |
HIV-1 NEF binds PACS-2 to assemble a multi-kinase cascade that triggers MHC-I downregulation: analysis using siRNA and knockout mice KM Atkins, L Thomas, RT Youker, MJ Harriff, F Pissani, H You, G Thomas J. Biol. Chem 283, 11772-11784, 2008 | 3 | 2008 |
Detectors for super-resolution & single-molecule fluorescence microscopies RT Youker Photon Counting—Fundamentals and Applications, 2018 | 2 | 2018 |
FKBP8 peptidyl-prolyl-isomerase activity manages a late stage of CFTR folding and stability DM Hutt, D Martino Roth, M Chalfant, RT Youker, J Matteson, JL Brodsky, ... J Biol Chem doi 10, 2012 | 2 | 2012 |
Fluorescence fluctuation techniques for the investigation of structure-function relationships of G-protein-coupled receptors RT Youker, D Voet Fluorescence Methods for Investigation of Living Cells and Microorganisms, 155, 2020 | 1 | 2020 |
SubVis: an interactive R package for exploring the effects of multiple substitution matrices on pairwise sequence alignment S Barlowe, HB Coan, RT Youker PeerJ 5, e3492, 2017 | 1 | 2017 |