| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 262 | 2019 |
| Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma H Nikbakht, E Panditharatna, LG Mikael, R Li, T Gayden, M Osmond, ... Nature communications 7 (1), 11185, 2016 | 239 | 2016 |
| Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas S Papillon-Cavanagh, C Lu, T Gayden, LG Mikael, D Bechet, ... Nature genetics 49 (2), 180-185, 2017 | 233 | 2017 |
| H3. 3K27M cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ... Cancer cell 32 (5), 684-700. e9, 2017 | 229 | 2017 |
| Elevated homocysteine reduces apolipoprotein AI expression in hyperhomocysteinemic mice and in males with coronary artery disease LG Mikael, J Genest Jr, R Rozen Circulation research 98 (4), 564-571, 2006 | 211 | 2006 |
| High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice KE Christensen, LG Mikael, KY Leung, N Lévesque, L Deng, Q Wu, ... The American journal of clinical nutrition 101 (3), 646-658, 2015 | 191 | 2015 |
| Stalled developmental programs at the root of pediatric brain tumors S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ... Nature genetics 51 (12), 1702-1713, 2019 | 185 | 2019 |
| Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ... Nature genetics 50 (12), 1650-1657, 2018 | 179 | 2018 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 175 | 2019 |
| Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 113 | 2020 |
| Moderately high intake of folic acid has a negative impact on mouse embryonic development LG Mikael, L Deng, L Paul, J Selhub, R Rozen Birth Defects Research Part A: Clinical and Molecular Teratology 97 (1), 47-52, 2013 | 101 | 2013 |
| Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice L Pickell, D Li, K Brown, LG Mikael, XL Wang, Q Wu, L Luo, ... Birth Defects Research Part A: Clinical and Molecular Teratology 85 (6), 531-541, 2009 | 78 | 2009 |
| Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice J Chan, L Deng, LG Mikael, J Yan, L Pickell, Q Wu, MA Caudill, R Rozen The American journal of clinical nutrition 91 (4), 1035-1043, 2010 | 73 | 2010 |
| TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw CC Gomes, T Gayden, A Bajic, OF Harraz, J Pratt, H Nikbakht, E Bareke, ... Nature communications 9 (1), 4572, 2018 | 72 | 2018 |
| Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia BC Schwahn, XL Wang, LG Mikael, Q Wu, J Cohn, H Jiang, KN Maclean, ... Atherosclerosis 195 (2), e100-e107, 2007 | 61 | 2007 |
| Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas R Salloum, MK McConechy, LG Mikael, C Fuller, R Drissi, M DeWire, ... Acta neuropathologica communications 5, 1-12, 2017 | 59 | 2017 |
| H3. 3 G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in giant cell tumor of bone S Khazaei, N De Jay, S Deshmukh, LD Hendrikse, W Jawhar, CCL Chen, ... Cancer discovery 10 (12), 1968-1987, 2020 | 53 | 2020 |
| Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness M Boileau, M Shirinian, T Gayden, AS Harutyunyan, CCL Chen, ... Nature communications 10 (1), 2891, 2019 | 51 | 2019 |
| Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-κB/iNOS LG Mikael, R Rozen Cardiovascular research 80 (1), 151-158, 2008 | 46 | 2008 |
| Molecular cloning of haemoglobin-binding protein HgbA in the outer membrane of Actinobacillus pleuropneumoniae R Srikumar, LG Mikael, PD Pawelek, A Khamessan, BF Gibbs, M Jacques, ... Microbiology 150 (6), 1723-1734, 2004 | 43 | 2004 |
