| A proficient enzyme A Radzicka, R Wolfenden Science 267 (5194), 90-93, 1995 | 1249 | 1995 |
| The depth of chemical time and the power of enzymes as catalysts R Wolfenden, MJ Snider Accounts of chemical research 34 (12), 938-945, 2001 | 1147 | 2001 |
| Affinities of amino acid side chains for solvent water R Wolfenden, L Andersson, PM Cullis, CCB Southgate Biochemistry 20 (4), 849-855, 1981 | 1041 | 1981 |
| Analog approaches to the structure of the transition state in enzyme reactions R Wolfenden Accounts of Chemical Research 5 (1), 10-18, 1972 | 840 | 1972 |
| Comparing the polarities of the amino acids: side-chain distribution coefficients between the vapor phase, cyclohexane, 1-octanol, and neutral aqueous solution A Radzicka, R Wolfenden Biochemistry 27 (5), 1664-1670, 1988 | 783 | 1988 |
| Transition state analog inhibitors and enzyme catalysis R Wolfenden Annual review of biophysics and bioengineering 5 (1), 271-306, 1976 | 588 | 1976 |
| Rates of uncatalyzed peptide bond hydrolysis in neutral solution and the transition state affinities of proteases A Radzicka, R Wolfenden Journal of the American Chemical Society 118 (26), 6105-6109, 1996 | 576 | 1996 |
| Transition state analogues for enzyme catalysis. R Wolfenden Nature 223 (5207), 1969 | 547 | 1969 |
| Hydrogen bonding, hydrophobicity, packing, and protein folding GD Rose, R Wolfenden Annual review of biophysics and biomolecular structure 22 (1), 381-415, 1993 | 523 | 1993 |
| Cytidine Deaminase. The 2· 3 Å crystal structure of an enzyme: transition-state analog complex L Betts, S Xiang, SA Short, R Wolfenden, CW Carter Jr Journal of molecular biology 235 (2), 635-656, 1994 | 477 | 1994 |
| The ribosome as an entropy trap A Sievers, M Beringer, MV Rodnina, R Wolfenden Proceedings of the National Academy of Sciences 101 (21), 7897-7901, 2004 | 433 | 2004 |
| Spontaneous hydrolysis of glycosides R Wolfenden, X Lu, G Young Journal of the American Chemical Society 120 (27), 6814-6815, 1998 | 419 | 1998 |
| The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases C Lad, NH Williams, R Wolfenden Proceedings of the National Academy of Sciences 100 (10), 5607-5610, 2003 | 351 | 2003 |
| Catalytic proficiency: the unusual case of OMP decarboxylase BG Miller, R Wolfenden Annual review of biochemistry 71 (1), 847-885, 2002 | 337 | 2002 |
| The time required for water attack at the phosphorus atom of simple phosphodiesters and of DNA GK Schroeder, C Lad, P Wyman, NH Williams, R Wolfenden Proceedings of the National Academy of Sciences 103 (11), 4052-4055, 2006 | 330 | 2006 |
| Binding of the by-product analog benzylsuccinic acid by carboxypeptidase A LD Byers, R Wolfenden Biochemistry 12 (11), 2070-2078, 1973 | 281 | 1973 |
| Interaction of the peptide bond with solvent water: a vapor phase analysis R Wolfenden Biochemistry 17 (1), 201-204, 1978 | 240 | 1978 |
| Anatomy of a proficient enzyme: the structure of orotidine 5′-monophosphate decarboxylase in the presence and absence of a potential transition state analog BG Miller, AM Hassell, R Wolfenden, MV Milburn, SA Short Proceedings of the National Academy of Sciences 97 (5), 2011-2016, 2000 | 237 | 2000 |
| Water, protein folding, and the genetic code RV Wolfenden, PM Cullis, CCF Southgate Science 206 (4418), 575-577, 1979 | 228 | 1979 |
| 1-Methyladenosine. Dimroth rearrangement and reversible reduction JB Macon, R Wolfenden Biochemistry 7 (10), 3453-3458, 1968 | 224 | 1968 |
