Mitchell Guttman
Mitchell Guttman
Verified email at lncrna.caltech.edu - Homepage
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Integrative genomics viewer
JT Robinson, H Thorvaldsdóttir, W Winckler, M Guttman, ES Lander, ...
Nature biotechnology 29 (1), 24-26, 2011
76332011
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ...
Nature 458 (7235), 223-227, 2009
37952009
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
AM Khalil, M Guttman, M Huarte, M Garber, A Raj, DR Morales, K Thomas, ...
Proceedings of the National Academy of Sciences 106 (28), 11667-11672, 2009
27282009
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ...
Cell 142 (3), 409-419, 2010
18972010
lincRNAs act in the circuitry controlling pluripotency and differentiation
M Guttman, J Donaghey, BW Carey, M Garber, JK Grenier, G Munson, ...
Nature 477 (7364), 295-300, 2011
18042011
Modular regulatory principles of large non-coding RNAs
M Guttman, JL Rinn
Nature 482 (7385), 339-346, 2012
17272012
Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs
M Guttman, M Garber, JZ Levin, J Donaghey, J Robinson, X Adiconis, ...
Nature biotechnology 28 (5), 503-510, 2010
12922010
Computational methods for transcriptome annotation and quantification using RNA-seq
M Garber, MG Grabherr, M Guttman, C Trapnell
Nature methods 8 (6), 469-477, 2011
10252011
A high-resolution map of human evolutionary constraint using 29 mammals
K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ...
Nature 478 (7370), 476-482, 2011
9892011
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells
S Loewer, MN Cabili, M Guttman, YH Loh, K Thomas, IH Park, M Garber, ...
Nature genetics 42 (12), 1113, 2010
8772010
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
JM Engreitz, A Pandya-Jones, P McDonel, A Shishkin, K Sirokman, ...
Science 341 (6147), 2013
7972013
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3
CA McHugh, CK Chen, A Chow, CF Surka, C Tran, P McDonel, ...
Nature 521 (7551), 232-236, 2015
6922015
Local regulation of gene expression by lncRNA promoters, transcription and splicing
JM Engreitz, JE Haines, EM Perez, G Munson, J Chen, M Kane, ...
Nature 539 (7629), 452-455, 2016
6392016
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
EL Van Nostrand, GA Pratt, AA Shishkin, C Gelboin-Burkhart, MY Fang, ...
Nature methods 13 (6), 508-514, 2016
6002016
Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins
M Guttman, P Russell, NT Ingolia, JS Weissman, ES Lander
Cell 154 (1), 240-251, 2013
5992013
A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor
K Suyama, I Shapiro, M Guttman, RB Hazan
Cancer cell 2 (4), 301-314, 2002
5622002
m6A RNA methylation promotes XIST-mediated transcriptional repression
DP Patil, CK Chen, BF Pickering, A Chow, C Jackson, M Guttman, ...
Nature 537 (7620), 369-373, 2016
5142016
Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA
S Schwartz, DA Bernstein, MR Mumbach, M Jovanovic, RH Herbst, ...
Cell 159 (1), 148-162, 2014
5002014
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
I Amit, M Garber, N Chevrier, AP Leite, Y Donner, T Eisenhaure, ...
Science 326 (5950), 257-263, 2009
4892009
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells
CA Gifford, MJ Ziller, H Gu, C Trapnell, J Donaghey, A Tsankov, ...
Cell 153 (5), 1149-1163, 2013
3682013
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