| Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors Y Uchida, S Ohtsuki, Y Katsukura, C Ikeda, T Suzuki, J Kamiie, T Terasaki Journal of neurochemistry 117 (2), 333-345, 2011 | 850 | 2011 |
| Contribution of carrier-mediated transport systems to the blood–brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and … S Ohtsuki, T Terasaki Pharmaceutical research 24, 1745-1758, 2007 | 553 | 2007 |
| Quantitative atlas of membrane transporter proteins: development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide … J Kamiie, S Ohtsuki, R Iwase, K Ohmine, Y Katsukura, K Yanai, Y Sekine, ... Pharmaceutical research 25, 1469-1483, 2008 | 550 | 2008 |
| Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry BC Collins, CL Hunter, Y Liu, B Schilling, G Rosenberger, SL Bader, ... Nature communications 8 (1), 291, 2017 | 500 | 2017 |
| Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual … S Ohtsuki, O Schaefer, H Kawakami, T Inoue, S Liehner, A Saito, ... Drug metabolism and Disposition 40 (1), 83-92, 2012 | 499 | 2012 |
| A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro S Hori, S Ohtsuki, K Hosoya, E Nakashima, T Terasaki Journal of neurochemistry 89 (2), 503-513, 2004 | 407 | 2004 |
| Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels R Shawahna, Y Uchida, X Decleves, S Ohtsuki, S Yousif, S Dauchy, ... Molecular pharmaceutics 8 (4), 1332-1341, 2011 | 394 | 2011 |
| Different core promoters possess distinct regulatory activities in the Drosophila embryo S Ohtsuki, M Levine, HN Cai Genes & development 12 (4), 547-556, 1998 | 262 | 1998 |
| Quantitative membrane protein expression at the blood–brain barrier of adult and younger cynomolgus monkeys K Ito, Y Uchida, S Ohtsuki, S Aizawa, H Kawakami, Y Katsukura, J Kamiie, ... Journal of pharmaceutical sciences 100 (9), 3939-3950, 2011 | 245 | 2011 |
| Quantitative atlas of blood–brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset Y Hoshi, Y Uchida, M Tachikawa, T Inoue, S Ohtsuki, T Terasaki Journal of pharmaceutical sciences 102 (9), 3343-3355, 2013 | 243 | 2013 |
| Role of blood–brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from … S Ohtsuki, H Asaba, H Takanaga, T Deguchi, K Hosoya, M Otagiri, ... Journal of neurochemistry 83 (1), 57-66, 2002 | 237 | 2002 |
| Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 … S Ohtsuki, C Ikeda, Y Uchida, Y Sakamoto, F Miller, F Glacial, X Decleves, ... Molecular pharmaceutics 10 (1), 289-296, 2013 | 232 | 2013 |
| The blood–brain barrier creatine transporter is a major pathway for supplying creatine to the brain S Ohtsuki, M Tachikawa, H Takanaga, H Shimizu, M Watanabe, K Hosoya, ... Journal of Cerebral Blood Flow & Metabolism 22 (11), 1327-1335, 2002 | 219 | 2002 |
| A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters … Y Uchida, M Tachikawa, W Obuchi, Y Hoshi, Y Tomioka, S Ohtsuki, ... Fluids and Barriers of the CNS 10, 1-22, 2013 | 218 | 2013 |
| New approaches to in vitro models of blood–brain barrier drug transport T Terasaki, S Ohtsuki, S Hori, H Takanaga, E Nakashima, K Hosoya Drug discovery today 8 (20), 944-954, 2003 | 204 | 2003 |
| Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide … H Kawakami, S Ohtsuki, J Kamiie, T Suzuki, T Abe, T Terasaki Journal of pharmaceutical sciences 100 (1), 341-352, 2011 | 201 | 2011 |
| Exogenous expression of claudin‐5 induces barrier properties in cultured rat brain capillary endothelial cells S Ohtsuki, S Sato, H Yamaguchi, M Kamoi, T Asashima, T Terasaki Journal of cellular physiology 210 (1), 81-86, 2007 | 200 | 2007 |
| Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK‐Mi and CK‐B suggest a novel neuron–glial relationship for brain energy homeostasis M Tachikawa, M Fukaya, T Terasaki, S Ohtsuki, M Watanabe European Journal of Neuroscience 20 (1), 144-160, 2004 | 198 | 2004 |
| GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo S Ohtsuki, M Levine Genes & development 12 (21), 3325-3330, 1998 | 191 | 1998 |
| Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells S Mori, H Takanaga, S Ohtsuki, T Deguchi, YS Kang, K Hosoya, ... Journal of Cerebral Blood Flow & Metabolism 23 (4), 432-440, 2003 | 189 | 2003 |
Terasaki Tetsuya, Ph.D.,University of Eastern Finland
