The reaction of thio acids with azides: a new mechanism and new synthetic applications N Shangguan, S Katukojvala, R Greenberg, LJ Williams Journal of the American Chemical Society 125 (26), 7754-7755, 2003 | 401 | 2003 |
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial T Gilewski, G Ragupathi, S Bhuta, LJ Williams, C Musselli, XF Zhang, ... Proceedings of the National Academy of Sciences 98 (6), 3270-3275, 2001 | 272 | 2001 |
Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains DM Coltart, AK Royyuru, LJ Williams, PW Glunz, D Sames, SD Kuduk, ... Journal of the American Chemical Society 124 (33), 9833-9844, 2002 | 212 | 2002 |
Mechanism of thio acid/azide amidation RV Kolakowski, N Shangguan, RR Sauers, LJ Williams Journal of the American Chemical Society 128 (17), 5695-5702, 2006 | 205 | 2006 |
Selective inhibition of human brain tumor cell proliferation via multifunctional quantum dot-based siRNA delivery J Jung, A Solanki, KA Memoli, K Kamei, H Kim, MA Drahl, LJ Williams, ... Angewandte Chemie (International ed. in English) 49 (1), 103, 2010 | 191 | 2010 |
Toward optimized carbohydrate-based anticancer vaccines: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewisy conjugates in mice V Kudryashov, PW Glunz, LJ Williams, S Hintermann, SJ Danishefsky, ... Proceedings of the National Academy of Sciences 98 (6), 3264-3269, 2001 | 155 | 2001 |
On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines G Ragupathi, DM Coltart, LJ Williams, F Koide, E Kagan, J Allen, C Harris, ... Proceedings of the National Academy of Sciences 99 (21), 13699-13704, 2002 | 151 | 2002 |
Induction of antibodies against GM2 ganglioside by immunizing melanoma patients using GM2-keyhole limpet hemocyanin+ QS21 vaccine: a dose-response study PB Chapman, DM Morrissey, KS Panageas, WB Hamilton, C Zhan, ... Clinical Cancer Research 6 (3), 874-879, 2000 | 127 | 2000 |
C C Fragmentation: Origins and Recent Applications MA Drahl, M Manpadi, LJ Williams Angewandte Chemie International Edition 52 (43), 11222-11251, 2013 | 102 | 2013 |
A formal synthesis of psymberin N Shangguan, S Kiren, LJ Williams Organic letters 9 (6), 1093-1096, 2007 | 93 | 2007 |
A Second Generation Synthesis of the MBr1 (Globo‐H) Breast Tumor Antigen: New Application of the n‐Pentenyl Glycoside Method for Achieving Complex … JR Allen, JG Allen, XF Zhang, LJ Williams, A Zatorski, G Ragupathi, ... Chemistry–A European Journal 6 (8), 1366-1375, 2000 | 87 | 2000 |
Probing cell-surface architecture through synthesis: an NMR-determined structural motif for tumor-associated mucins DH Live, LJ Williams, SD Kuduk, JB Schwarz, PW Glunz, XT Chen, ... Proceedings of the National Academy of Sciences 96 (7), 3489-3493, 1999 | 86 | 1999 |
Design and synthesis of Ley-bearing glycopeptides that mimic cell surface Ley mucin glycoprotein architecture PW Glunz, S Hintermann, LJ Williams, JB Schwarz, SD Kuduk, ... Journal of the American Chemical Society 122 (30), 7273-7279, 2000 | 84 | 2000 |
Recent developments in allene-based synthetic methods. H Kim, LJ Williams Current Opinion in Drug Discovery & Development 11 (6), 870-894, 2008 | 81 | 2008 |
Thio acid/azide amidation: An improved route to N-acyl sulfonamides KN Barlett, RV Kolakowski, S Katukojvala, LJ Williams Organic letters 8 (5), 823-826, 2006 | 79 | 2006 |
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using … ZG Wang, LJ Williams, XF Zhang, A Zatorski, V Kudryashov, G Ragupathi, ... Proceedings of the National Academy of Sciences 97 (6), 2719-2724, 2000 | 75 | 2000 |
Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof S Danishefsky, D Sames, S Hintermann, X Chen, J Schwarz, P Glunz, ... US Patent App. 10/600,012, 2004 | 69 | 2004 |
Spirodiepoxides in total synthesis: epoxomicin S Katukojvala, KN Barlett, SD Lotesta, LJ Williams Journal of the American Chemical Society 126 (47), 15348-15349, 2004 | 67 | 2004 |
Allene Synthesis via C− C Fragmentation: Method and Mechanistic Insight RV Kolakowski, M Manpadi, Y Zhang, TJ Emge, LJ Williams Journal of the American Chemical Society 131 (36), 12910-12911, 2009 | 61 | 2009 |
A Spirodiepoxide-Based Strategy to the A− B Ring System of Pectenotoxin 4 SD Lotesta, Y Hou, LJ Williams Organic letters 9 (5), 869-872, 2007 | 57 | 2007 |