Jacob A. Sloane
Jacob A. Sloane
Assistant Professor of Neurology, Harvard Medical School
Verified email at
Cited by
Cited by
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2
JA Sloane, C Batt, Y Ma, ZM Harris, B Trapp, T Vartanian
Proceedings of the National Academy of Sciences 107 (25), 11555-11560, 2010
Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis
Y Ma, J Li, I Chiu, Y Wang, JA Sloane, J Lü, B Kosaras, RL Sidman, ...
The Journal of cell biology 175 (2), 209-215, 2006
Increased microglial activation and protein nitration in white matter of the aging monkey☆
JA Sloane, W Hollander, MB Moss, DL Rosene, CR Abraham
Neurobiology of aging 20 (4), 395-405, 1999
Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals
JS Cameron, L Alexopoulou, JA Sloane, AB DiBernardo, Y Ma, B Kosaras, ...
Journal of Neuroscience 27 (47), 13033-13041, 2007
Neuroinflammatory component of gray matter pathology in multiple sclerosis
E Herranz, C Gianń, C Louapre, CA Treaba, ST Govindarajan, ...
Annals of neurology 80 (5), 776-790, 2016
The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS
CD Chen, JA Sloane, H Li, N Aytan, EL Giannaris, E Zeldich, JD Hinman, ...
Journal of Neuroscience 33 (5), 1927-1939, 2013
In vivo characterization of cortical and white matter neuroaxonal pathology in early multiple sclerosis
T Granberg, Q Fan, CA Treaba, R Ouellette, E Herranz, G Mangeat, ...
Brain 140 (11), 2912-2926, 2017
A gradient in cortical pathology in multiple sclerosis by in vivo quantitative 7 T imaging
C Mainero, C Louapre, ST Govindarajan, C Gianń, AS Nielsen, ...
Brain 138 (4), 932-945, 2015
Metalloendopeptidase EC 3.4. 24.15 is necessary for Alzheimer's amyloid-β peptide degradation
R Yamin, EG Malgeri, JA Sloane, WT McGraw, CR Abraham
Journal of Biological Chemistry 274 (26), 18777-18784, 1999
Lack of correlation between plaque burden and cognition in the aged monkey
JA Sloane, MF Pietropaolo, DL Rosene, MB Moss, A Peters, T Kemper, ...
Acta neuropathologica 94, 471-478, 1997
A clear and present danger: endogenous ligands of Toll-like receptors
JA Sloane, D Blitz, Z Margolin, T Vartanian
Neuromolecular medicine 12, 149-163, 2010
WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination
HJ Kim, AB DiBernardo, JA Sloane, MN Rasband, D Solomon, B Kosaras, ...
Journal of Neuroscience 26 (21), 5849-5859, 2006
Age‐dependent myelin degeneration and proteolysis of oligodendrocyte proteins is associated with the activation of calpain‐1 in the rhesus monkey
JA Sloane, JD Hinman, M Lubonia, W Hollander, CR Abraham
Journal of neurochemistry 84 (1), 157-168, 2003
Regulation of remyelination in multiple sclerosis
KA Hanafy, JA Sloane
FEBS letters 585 (23), 3821-3828, 2011
Astrocytic hypertrophy and altered GFAP degradation with age in subcortical white matter of the rhesus monkey
JA Sloane, W Hollander, DL Rosene, MB Moss, T Kemper, CR Abraham
Brain research 862 (1-2), 1-10, 2000
Evidence for local production of acute phase response apolipoprotein serum amyloid A in Alzheimer's disease brain
J Liang, JA Sloane, JM Wells, CR Abraham, RE Fine, JD Sipe
Neuroscience letters 225 (2), 73-76, 1997
COVID-19 in teriflunomide-treated patients with multiple sclerosis
AH Maghzi, MK Houtchens, P Preziosa, C Ionete, BD Beretich, ...
Journal of neurology 267, 2790-2796, 2020
Longitudinal characterization of cortical lesion development and evolution in multiple sclerosis with 7.0-T MRI
CA Treaba, TE Granberg, MP Sormani, E Herranz, RA Ouellette, ...
Radiology 291 (3), 740-749, 2019
Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised …
JF Foley, G Defer, LZ Ryerson, JA Cohen, DL Arnold, H Butzkueven, ...
The Lancet Neurology 21 (7), 608-619, 2022
JC virus reactivation during prolonged natalizumab monotherapy for multiple sclerosis
S Chalkias, X Dang, E Bord, MC Stein, RP Kinkel, JA Sloane, M Donnelly, ...
Annals of neurology 75 (6), 925-934, 2014
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