| Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models I Aiba, JL Noebels Science translational medicine 7 (282), 282ra46-282ra46, 2015 | 286 | 2015 |
| Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells WB Tsai, I Aiba, Y Long, HK Lin, L Feun, N Savaraj, MT Kuo Cancer research 72 (10), 2622-2633, 2012 | 223 | 2012 |
| Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1α/Sp4 WB Tsai, I Aiba, S Lee, L Feun, N Savaraj, MT Kuo Molecular cancer therapeutics 8 (12), 3223-3233, 2009 | 148 | 2009 |
| Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells IS Song, HHW Chen, I Aiba, A Hossain, ZD Liang, LWJ Klomp, MT Kuo Molecular pharmacology 74 (3), 705-713, 2008 | 106 | 2008 |
| Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases I Aiba, T Yamasaki, T Shinki, S Izumi, K Yamamoto, S Yamada, H Terato, ... Steroids 71 (10), 849-856, 2006 | 93 | 2006 |
| Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons I Aiba, CW Shuttleworth The Journal of physiology 590 (22), 5877-5893, 2012 | 76 | 2012 |
| Isolated P/Q calcium channel deletion in layer VI corticothalamic neurons generates absence epilepsy VC Bomben, I Aiba, J Qian, MD Mark, S Herlitze, JL Noebels Journal of Neuroscience 36 (2), 405-418, 2016 | 62 | 2016 |
| Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model A Hatcher, K Yu, J Meyer, I Aiba, B Deneen, JL Noebels The Journal of clinical investigation 130 (5), 2286-2300, 2020 | 59 | 2020 |
| Elevated GSH level increases cadmium resistance through down-regulation of Sp1-dependent expression of the cadmium transporter ZIP8 I Aiba, A Hossain, MT Kuo Molecular pharmacology 74 (3), 823-833, 2008 | 59 | 2008 |
| Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death I Aiba, XHT Wehrens, JL Noebels Proceedings of the National Academy of Sciences 113 (33), E4895-E4903, 2016 | 53 | 2016 |
| Spreading Depression and Related Events Are Significant Sources of Neuronal Zn2+ Release and Accumulation RE Carter, I Aiba, RM Dietz, CT Sheline, CW Shuttleworth Journal of Cerebral Blood Flow & Metabolism 31 (4), 1073-1084, 2011 | 45 | 2011 |
| Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy HHW Chen, WC Chen, ZD Liang, WB Tsai, Y Long, I Aiba, S Fu, ... Expert opinion on therapeutic targets 19 (10), 1307-1317, 2015 | 44 | 2015 |
| Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance JL Seidel, M Faideau, I Aiba, U Pannasch, C Escartin, N Rouach, ... Glia 63 (1), 91-103, 2015 | 36 | 2015 |
| Synaptic release and extracellular actions of Zn2+ limit propagation of spreading depression and related events in vitro and in vivo I Aiba, AP Carlson, CT Sheline, CW Shuttleworth Journal of neurophysiology 107 (3), 1032-1041, 2012 | 36 | 2012 |
| Release, neuronal effects and removal of extracellular β‐nicotinamide adenine dinucleotide (β‐NAD+) in the rat brain L Durnin, Y Dai, I Aiba, CW Shuttleworth, IA Yamboliev, ... European Journal of Neuroscience 35 (3), 423-435, 2012 | 27 | 2012 |
| Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization I Aiba, JL Noebels Brain 144 (9), 2863-2878, 2021 | 26 | 2021 |
| Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation RN Curry, I Aiba, J Meyer, B Lozzi, Y Ko, MF McDonald, A Rosenbaum, ... Neuron 111 (5), 682-695. e9, 2023 | 21 | 2023 |
| Characterization of inhibitory GABA-A receptor activation during spreading depolarization in brain slice I Aiba, CW Shuttleworth PLoS One 9 (10), e110849, 2014 | 19 | 2014 |
| Intracellular dialysis disrupts Zn2+ dynamics and enables selective detection of Zn2+ influx in brain slice preparations I Aiba, AK West, CT Sheline, CW Shuttleworth Journal of neurochemistry 125 (6), 822-831, 2013 | 10 | 2013 |
| SUDEP animal Models AM Goldman, G Buchanan, I Aiba, JL Noebels Models of Seizures and Epilepsy, 1007-1018, 2017 | 9 | 2017 |
