Haim Cohen
Haim Cohen
Biology professor
Verified email at - Homepage
Cited by
Cited by
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz, KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, ...
Nature 425 (6954), 191-196, 2003
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ...
science 303 (5666), 2011-2015, 2004
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen, C Miller, KJ Bitterman, NR Wall, B Hekking, B Kessler, ...
science 305 (5682), 390-392, 2004
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
KJ Bitterman, RM Anderson, HY Cohen, M Latorre-Esteves, DA Sinclair
Journal of Biological Chemistry 277 (47), 45099-45107, 2002
The sirtuin SIRT6 regulates lifespan in male mice
Y Kanfi, S Naiman, G Amir, V Peshti, G Zinman, L Nahum, Z Bar-Joseph, ...
Nature 483 (7388), 218-221, 2012
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
HY Cohen, S Lavu, KJ Bitterman, B Hekking, TA Imahiyerobo, C Miller, ...
Molecular cell 13 (5), 627-638, 2004
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels
RM Anderson, KJ Bitterman, JG Wood, O Medvedik, H Cohen, SS Lin, ...
Journal of Biological Chemistry 277 (21), 18881-18890, 2002
SIRT6 protects against pathological damage caused by diet‐induced obesity
Y Kanfi, V Peshti, R Gil, S Naiman, L Nahum, E Levin, N Kronfeld‐Schor, ...
Aging cell 9 (2), 162-173, 2010
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation
M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ...
Cell metabolism 29 (4), 871-885. e5, 2019
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
K Schmeisser, J Mansfeld, D Kuhlow, S Weimer, S Priebe, I Heiland, ...
Nature chemical biology 9 (11), 693-700, 2013
Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment
T Peled, H Shoham, D Aschengrau, D Yackoubov, G Frei, B Lerrer, ...
Experimental hematology 40 (4), 342-355. e1, 2012
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
H Cohen, DA Sinclair
Proceedings of the National Academy of Sciences 98 (6), 3174-3179, 2001
Regulation of SIRT6 protein levels by nutrient availability
Y Kanfi, R Shalman, V Peshti, SN Pilosof, YM Gozlan, KJ Pearson, ...
FEBS letters 582 (5), 543-548, 2008
Mammalian conserved ADAR targets comprise only a small fragment of the human editosome
Y Pinto, HY Cohen, EY Levanon
Genome biology 15, 1-15, 2014
Multiple regulatory layers of SREBP1/2 by SIRT6
S Elhanati, Y Kanfi, A Varvak, A Roichman, I Carmel-Gross, S Barth, ...
Cell reports 4 (5), 905-912, 2013
Regulation of SIRT1 protein levels by nutrient availability
Y Kanfi, V Peshti, YM Gozlan, M Rathaus, R Gil, HY Cohen
FEBS letters 582 (16), 2417-2423, 2008
SIRT6 exhibits nucleosome-dependent deacetylase activity
R Gil, S Barth, Y Kanfi, HY Cohen
Nucleic acids research 41 (18), 8537-8545, 2013
Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation
AD Amsel, M Rathaus, N Kronman, HY Cohen
Proceedings of the National Academy of Sciences 105 (13), 5117-5122, 2008
Restoration of energy homeostasis by SIRT6 extends healthy lifespan
A Roichman, S Elhanati, MA Aon, I Abramovich, A Di Francesco, ...
Nature communications 12 (1), 3208, 2021
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation
Y Li, T Yokota, V Gama, T Yoshida, JA Gomez, K Ishikawa, H Sasaguri, ...
Cell Death & Differentiation 14 (12), 2058-2067, 2007
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