Protein O-mannosylation S Strahl-Bolsinger, M Gentzsch, W Tanner Biochimica et Biophysica Acta (BBA)-General Subjects 1426 (2), 297-307, 1999 | 348 | 1999 |
Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis DM Cholon, NL Quinney, ML Fulcher, CR Esther, J Das, NV Dokholyan, ... Science translational medicine 6 (246), 246ra96-246ra96, 2014 | 268 | 2014 |
The PMT gene family: protein O‐glycosylation in Saccharomyces cerevisiae is vital. M Gentzsch, W Tanner The EMBO journal 15 (21), 5752-5759, 1996 | 268 | 1996 |
Specific Labelling of Cell Wall Proteins by Biotinylation. Identification of Four Covalently Linked O‐mannosylated Proteins of Saccharomyces cerevisiae V Mrsă, T Seidl, M Gentzsch, W Tanner Yeast 13 (12), 1145-1154, 1997 | 262 | 1997 |
Endocytic trafficking routes of wild type and ΔF508 cystic fibrosis transmembrane conductance regulator M Gentzsch, XB Chang, L Cui, Y Wu, VV Ozols, A Choudhury, RE Pagano, ... Molecular biology of the cell 15 (6), 2684-2696, 2004 | 249 | 2004 |
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ... Nature chemical biology 6 (1), 25-33, 2010 | 243 | 2010 |
Domain interdependence in the biosynthetic assembly of CFTR L Cui, L Aleksandrov, XB Chang, YX Hou, L He, T Hegedus, M Gentzsch, ... Journal of molecular biology 365 (4), 981-994, 2007 | 211 | 2007 |
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration LA Clunes, CM Davies, RD Coakley, AA Aleksandrov, AG Henderson, ... The FASEB Journal 26 (2), 533-545, 2012 | 200 | 2012 |
Protein-O-glycosylation in yeast: protein-specific mannosyltransferases M Gentzsch, W Tanner Glycobiology 7 (4), 481-486, 1997 | 178 | 1997 |
The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins M Gentzsch, L Cui, A Mengos, X Chang, JH Chen, JR Riordan Journal of Biological Chemistry 278 (8), 6440-6449, 2003 | 132 | 2003 |
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR WR Thelin, Y Chen, M Gentzsch, SM Kreda, JL Sallee, CO Scarlett, ... The Journal of clinical investigation 117 (2), 364-374, 2007 | 100 | 2007 |
Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases EA Gaillard, P Kota, M Gentzsch, NV Dokholyan, MJ Stutts, R Tarran Pflügers Archiv-European Journal of Physiology 460 (1), 1-17, 2010 | 99 | 2010 |
The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel M Gentzsch, H Dang, Y Dang, A Garcia-Caballero, H Suchindran, ... Journal of Biological Chemistry 285 (42), 32227-32232, 2010 | 98 | 2010 |
Regulatory insertion removal restores maturation, stability and function of ΔF508 CFTR AA Aleksandrov, P Kota, LA Aleksandrov, L He, T Jensen, L Cui, ... Journal of molecular biology 401 (2), 194-210, 2010 | 98 | 2010 |
Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures DM Cholon, WK O'Neal, SH Randell, JR Riordan, M Gentzsch American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (3 …, 2010 | 97 | 2010 |
Protein O-glycosylation in yeast: the PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity M Lussier, M Gentzsch, AM Sdicu, H Bussey, W Tanner Journal of Biological Chemistry 270 (6), 2770-2775, 1995 | 95 | 1995 |
CFTR modulator theratyping: current status, gaps and future directions JP Clancy, CU Cotton, SH Donaldson, GM Solomon, DR VanDevanter, ... Journal of Cystic Fibrosis 18 (1), 22-34, 2019 | 93 | 2019 |
Novel human bronchial epithelial cell lines for cystic fibrosis research ML Fulcher, SE Gabriel, JC Olsen, JR Tatreau, M Gentzsch, E Livanos, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (1 …, 2009 | 92 | 2009 |
Pharmacological rescue of conditionally reprogrammed cystic fibrosis bronchial epithelial cells M Gentzsch, SE Boyles, C Cheluvaraju, IG Chaudhry, NL Quinney, C Cho, ... American journal of respiratory cell and molecular biology 56 (5), 568-574, 2017 | 82 | 2017 |
Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTR AA Aleksandrov, P Kota, L Cui, T Jensen, AE Alekseev, S Reyes, L He, ... Journal of molecular biology 419 (1-2), 41-60, 2012 | 82 | 2012 |