Photochemical tools for remote control of ion channels in excitable cells RH Kramer, JJ Chambers, D Trauner Nature chemical biology 1 (7), 360-365, 2005 | 157 | 2005 |
Light-Induced Depolarization of Neurons Using a Modified Shaker K+ Channel and a Molecular Photoswitch JJ Chambers, MR Banghart, D Trauner, RH Kramer Journal of neurophysiology 96 (5), 2792-2796, 2006 | 146 | 2006 |
Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT2A/2C receptor agonists JJ Chambers, DM Kurrasch-Orbaugh, MA Parker, DE Nichols Journal of medicinal chemistry 44 (6), 1003-1010, 2001 | 134 | 2001 |
A positive feedback synapse from retinal horizontal cells to cone photoreceptors SL Jackman, N Babai, JJ Chambers, WB Thoreson, RH Kramer PLoS biology 9 (5), e1001057, 2011 | 108 | 2011 |
A homology-based model of the human 5-HT2A receptor derived from an in silico activated G-protein coupled receptor JJ Chambers, DE Nichols Journal of computer-aided molecular design 16, 511-520, 2002 | 73 | 2002 |
A photoinduced, benzyne click reaction AW Gann, JW Amoroso, VJ Einck, WP Rice, JJ Chambers, NA Schnarr Organic letters 16 (7), 2003-2005, 2014 | 71 | 2014 |
Engineering a Light-Regulated GABAA Receptor for Optical Control of Neural Inhibition WC Lin, CM Davenport, A Mourot, D Vytla, CM Smith, KA Medeiros, ... ACS chemical biology 9 (7), 1414-1419, 2014 | 69 | 2014 |
QUAREP‐LiMi: A community‐driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy G Nelson, U Boehm, S Bagley, P Bajcsy, J Bischof, CM Brown, A Dauphin, ... Journal of microscopy 284 (1), 56-73, 2021 | 56 | 2021 |
DivIVA concentrates mycobacterial cell envelope assembly for initiation and stabilization of polar growth ES Melzer, CE Sein, JJ Chambers, MS Siegrist Cytoskeleton 75 (12), 498-507, 2018 | 52 | 2018 |
Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model M Hammer, M Huisman, A Rigano, U Boehm, JJ Chambers, N Gaudreault, ... Nature methods 18 (12), 1427-1440, 2021 | 50 | 2021 |
Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk O Afonso, CM Castellani, LP Cheeseman, JG Ferreira, B Orr, LT Ferreira, ... Elife 8, e47646, 2019 | 48 | 2019 |
Photochemically knocking out glutamate receptors in vivo JJ Chambers, H Gouda, DM Young, ID Kuntz, M Pamela Journal of the American Chemical Society 126 (43), 13886-13887, 2004 | 43 | 2004 |
Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif MS Eriksen, O Nikolaienko, EI Hallin, S Grødem, HJ Bustad, MI Flydal, ... The FEBS journal 288 (9), 2930-2955, 2021 | 36 | 2021 |
Photosensitive Molecules for Controlling Biological Function JJ Chambers, RH Kramer Humana Press, 2011 | 32 | 2011 |
Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT2A/2C receptor ligands JJ Chambers, JC Parrish, NH Jensen, DM Kurrasch-Orbaugh, ... Journal of medicinal chemistry 46 (16), 3526-3535, 2003 | 32 | 2003 |
C-(4, 5, 6-trimethoxyindan-1-yl) methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor TH McLean, JJ Chambers, JC Parrish, MR Braden, D Marona-Lewicka, ... Journal of medicinal chemistry 49 (14), 4269-4274, 2006 | 30 | 2006 |
Anionic polymers promote mitochondrial targeting of delocalized lipophilic cations Z Jiang, H Liu, H He, N Yadava, JJ Chambers, S Thayumanavan Bioconjugate chemistry 31 (5), 1344-1353, 2020 | 28 | 2020 |
Translocation of the 5-alkoxy substituent of 2, 5-dialkoxyarylalkylamines to the 6-position: effects on 5-HT2A/2C receptor affinity JJ Chambers, DM Kurrasch-Orbaugh, DE Nichols Bioorganic & medicinal chemistry letters 12 (15), 1997-1999, 2002 | 25 | 2002 |
Light‐Activated Ion Channels for Remote Control of Neural Activity JJ Chambers, RH Kramer Methods in cell biology 90, 217-232, 2008 | 24 | 2008 |
Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications A Rigano, S Ehmsen, SU Öztürk, J Ryan, A Balashov, M Hammer, K Kirli, ... Nature Methods 18 (12), 1489-1495, 2021 | 22 | 2021 |