| Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer S Bullman, CS Pedamallu, E Sicinska, TE Clancy, X Zhang, D Cai, ... Science 358 (6369), 1443-1448, 2017 | 1180 | 2017 |
| Genomic and Functional Approaches to Understanding Cancer Aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer Cell, 2018 | 859 | 2018 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 633 | 2014 |
| Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas FX Schaub, V Dhankani, AC Berger, M Trivedi, AB Richardson, R Shaw, ... Cell systems 6 (3), 282-300. e2, 2018 | 364 | 2018 |
| Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers X Zhang, PS Choi, JM Francis, M Imielinski, H Watanabe, AD Cherniack, ... Nature genetics 48 (2), 176-182, 2016 | 345 | 2016 |
| Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression R Cowper-Sal, X Zhang, JB Wright, SD Bailey, MD Cole, J Eeckhoute, ... Nature genetics 44 (11), 1191-1198, 2012 | 330 | 2012 |
| PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer L Magnani, EB Ballantyne, X Zhang, M Lupien PLoS genetics 7 (11), e1002368, 2011 | 221 | 2011 |
| ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters SD Bailey, X Zhang, K Desai, M Aid, O Corradin, R Cowper-Sal, ... Nature communications 2, 2015 | 213 | 2015 |
| Growth factor stimulation induces a distinct ERα cistrome underlying breast cancer endocrine resistance M Lupien, CA Meyer, ST Bailey, J Eeckhoute, J Cook, T Westerling, ... Genes & development 24 (19), 2219-2227, 2010 | 212 | 2010 |
| Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors GD Grant, L Brooks, X Zhang, JM Mahoney, V Martyanov, TA Wood, ... Molecular biology of the cell 24 (23), 3634-3650, 2013 | 194 | 2013 |
| Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer L Magnani, A Stoeck, X Zhang, A Lánczky, AC Mirabella, TL Wang, ... Proceedings of the National Academy of Sciences 110 (16), E1490-E1499, 2013 | 190 | 2013 |
| Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24. 3 prostate cancer risk locus X Zhang, R Cowper-Sal, SD Bailey, JH Moore, M Lupien Genome research 22 (8), 1437-1446, 2012 | 130 | 2012 |
| Somatic superenhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor X Zhang, PS Choi, JM Francis, GF Gao, JD Campbell, A Ramachandran, ... Cancer discovery 8 (1), 108-125, 2018 | 114 | 2018 |
| Laying a solid foundation for Manhattan–‘setting the functional basis for the post-GWAS era’ X Zhang, SD Bailey, M Lupien Trends in Genetics 30 (4), 140-149, 2014 | 107 | 2014 |
| The protective role of DOT1L in UV-induced melanomagenesis B Zhu, S Chen, H Wang, C Yin, C Han, C Peng, Z Liu, L Wan, X Zhang, ... Nature communications 9 (1), 259, 2018 | 80 | 2018 |
| Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence Z Wu, J Zhou, X Zhang, Z Zhang, Y Xie, J bin Liu, ZV Ho, A Panda, X Qiu, ... Nature Genetics 53 (6), 881-894, 2021 | 47 | 2021 |
| Illuminating the noncoding genome in cancer X Zhang, M Meyerson Nature Cancer 1 (9), 864-872, 2020 | 45 | 2020 |
| Copy number alterations unmasked as enhancer hijackers R Beroukhim, X Zhang, M Meyerson Nature genetics 49 (1), 5, 2017 | 42 | 2017 |
| Multi-Omics analysis identifies MGA as a negative regulator of the MYC pathway in lung adenocarcinoma P Llabata, Y Mitsuishi, PS Choi, D Cai, JM Francis, M Torres-Diz, ... Molecular Cancer Research, 2019 | 39 | 2019 |
| Human somatic cell mutagenesis creates genetically tractable sarcomas SD Molyneux, PD Waterhouse, D Shelton, YW Shao, CM Watling, ... Nature genetics 46 (9), 964-972, 2014 | 36 | 2014 |
Mathieu Lupien, Ph.D.Senior Scientist/Professor, Princess Margaret Cancer Centreכתובת אימייל מאומתת בדומיין uhnresearch.ca
