Raymond Deshaies
Raymond Deshaies
Senior Vice President of Global Research, Amgen
Verified email at - Homepage
Cited by
Cited by
RING domain E3 ubiquitin ligases
RJ Deshaies, CAP Joazeiro
Annual review of biochemistry 78, 399-434, 2009
Function and regulation of cullin–RING ubiquitin ligases
MD Petroski, RJ Deshaies
Nature reviews Molecular cell biology 6 (1), 9-20, 2005
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
RJ Deshaies, BD Koch, M Werner-Washburne, EA Craig, R Schekman
Nature 332 (6167), 800-805, 1988
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
KM Sakamoto, KB Kim, A Kumagai, F Mercurio, CM Crews, RJ Deshaies
Proceedings of the National Academy of Sciences 98 (15), 8554-8559, 2001
How proteolysis drives the cell cycle
RW King, RJ Deshaies, JM Peters, MW Kirschner
Science 274 (5293), 1652-1659, 1996
SCF and Cullin/Ring H2-based ubiquitin ligases
RJ Deshaies
Annual review of cell and developmental biology 15 (1), 435-467, 1999
Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26S Proteasome
R Verma, L Aravind, R Oania, WH McDonald, JR Yates III, EV Koonin, ...
Science 298 (5593), 611-615, 2002
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
RMR Feldman, CC Correll, KB Kaplan, RJ Deshaies
Cell 91 (2), 221-230, 1997
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
W Shou, JH Seol, A Shevchenko, C Baskerville, D Moazed, ZWS Chen, ...
Cell 97 (2), 233-244, 1999
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
GA Cope, GSB Suh, L Aravind, SE Schwarz, SL Zipursky, EV Koonin, ...
Science 298 (5593), 608-611, 2002
Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome
S Lyapina, G Cope, A Shevchenko, G Serino, T Tsuge, C Zhou, DA Wolf, ...
Science 292 (5520), 1382-1385, 2001
Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes
R Verma, S Chen, R Feldman, D Schieltz, J Yates, J Dohmen, ...
Molecular biology of the cell 11 (10), 3425-3439, 2000
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase
R Verma, RS Annan, MJ Huddleston, SA Carr, G Reynard, RJ Deshaies
Science 278 (5337), 455-460, 1997
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
Z Skrott, M Mistrik, KK Andersen, S Friis, D Majera, J Gursky, T Ozdian, ...
Nature 552 (7684), 194-199, 2017
Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response
C Schwechheimer, G Serino, J Callis, WL Crosby, S Lyapina, ...
Science 292 (5520), 1379-1382, 2001
Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system
R Verma, R Oania, J Graumann, RJ Deshaies
Cell 118 (1), 99-110, 2004
A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.
RJ Deshaies, R Schekman
The Journal of cell biology 105 (2), 633-645, 1987
Cdc53/cullin and the essential Hrt1 RING–H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
JH Seol, RMR Feldman, W Zachariae, A Shevchenko, CC Correll, ...
Genes & development 13 (12), 1614-1626, 1999
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells
SK Radhakrishnan, CS Lee, P Young, A Beskow, JY Chan, RJ Deshaies
Molecular cell 38 (1), 17-28, 2010
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
AF Straight, W Shou, GJ Dowd, CW Turck, RJ Deshaies, AD Johnson, ...
Cell 97 (2), 245-256, 1999
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