עקוב אחר
Poorva Sandlesh
Poorva Sandlesh
Postdoctoral Fellow
כתובת אימייל מאומתת בדומיין pennmedicine.upenn.edu
כותרת
צוטט על ידי
צוטט על ידי
שנה
Structure and function of the histone chaperone FACT–Resolving FACTual issues
K Gurova, HW Chang, ME Valieva, P Sandlesh, VM Studitsky
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (9), 892-904, 2018
992018
Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models
JKT Dermawan, M Hitomi, DJ Silver, Q Wu, P Sandlesh, AE Sloan, ...
Cancer research 76 (8), 2432-2442, 2016
722016
TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells
K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ...
Elife 7, e30842, 2018
422018
TIGIT and PD-1 immune checkpoint pathways are associated with patient outcome and anti-tumor immunity in glioblastoma
I Raphael, R Kumar, LH McCarl, K Shoger, L Wang, P Sandlesh, ...
Frontiers in immunology 12, 637146, 2021
412021
Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene
P Sandlesh, T Juang, A Safina, MJ Higgins, KV Gurova
PLoS One 13 (6), e0199785, 2018
342018
Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles
N Ludwig, A Rao, P Sandlesh, SS Yerneni, AD Swain, KM Bullock, ...
Neuro-oncology 24 (2), 197-209, 2022
252022
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
JR Leistico, P Saini, CR Futtner, M Hejna, Y Omura, PN Soni, P Sandlesh, ...
Cell reports 34 (13), 2021
132021
Prevention of chromatin destabilization by FACT is crucial for malignant transformation
P Sandlesh, A Safina, I Goswami, L Prendergast, S Rosario, EC Gomez, ...
Iscience 23 (6), 2020
132020
Machine learning identification of immunotherapy targets in low-grade glioma using RNA sequencing expression data
P Agarwal, OM Beale, X Zhang, P Sandlesh, E Jaman, N Amankulor
World Neurosurgery 163, e349-e362, 2022
62022
FACT maintains nucleosomes during transcription and stem cell viability in adult mice
I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ...
EMBO reports 23 (4), e53684, 2022
62022
History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas
E Jaman, X Zhang, P Sandlesh, A Habib, J Allen, RG Saraiya, ...
Journal of Neuro-Oncology 155, 133-141, 2021
42021
In vivo efficacy of decitabine as a natural killer cell–mediated immunotherapy against isocitrate dehydrogenase mutant gliomas
X Zhang, WJ Kim, AV Rao, E Jaman, CP Deibert, P Sandlesh, K Krueger, ...
Neurosurgical Focus 52 (2), E3, 2022
32022
FACT-mediated maintenance of chromatin integrity during transcription is essential for viability of mammalian stem cells
I Goswami
State University of New York at Buffalo, 2021
12021
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis
A Rao, X Zhang, A Cillo, JH Sussman, P Sandlesh, AC Tarbay, ...
bioRxiv, 2024.04. 09.588752, 2024
2024
FACT-mediated maintenance of chromatin integrity during transcription is essential for mammalian stem cell viability
I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ...
bioRxiv, 2021.06. 21.449309, 2021
2021
Understanding the role of histone chaperone FACT in mammalian cells using a conditional FACT knockout mouse model
I Goswami, P Sandlesh, A Safina, K Gurova
TRANSGENIC RESEARCH 29 (SUPPL 1), 14-14, 2020
2020
Induction of nucleosome disassembly with small molecules as a novel anti-cancer approach
A Safina, P Sandlesh, J Wang, KV Gurova
Cancer Research 80 (16_Supplement), 1747-1747, 2020
2020
Conditional knockout of histone chaperone FACT in mice: Consequences for normal tissues
MA Ito, P Sandlesh, I Goswami, LA Prendergast, K Gurova
Cancer Research 79 (13_Supplement), 5193-5193, 2019
2019
Generation of a Conditional Knockout of FACT Subunit SSRP1 Mouse Model to Study the Consequences of FACT Inactivation
P Sandlesh
State University of New York at Buffalo, 2018
2018
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–19