| The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2170 | 2010 |
| A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), 2016 | 709 | 2016 |
| CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast M Costanzo, JL Nishikawa, X Tang, JS Millman, O Schub, K Breitkreuz, ... Cell 117 (7), 899-913, 2004 | 478 | 2004 |
| Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress JM Tkach, A Yimit, AY Lee, M Riffle, M Costanzo, D Jaschob, JA Hendry, ... Nature cell biology 14 (9), 966-976, 2012 | 405 | 2012 |
| Widespread expansion of protein interaction capabilities by alternative splicing X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ... Cell 164 (4), 805-817, 2016 | 335 | 2016 |
| Quantitative analysis of fitness and genetic interactions in yeast on a genome scale A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ... Nature methods 7 (12), 1017-1024, 2010 | 329 | 2010 |
| Systematic exploration of essential yeast gene function with temperature-sensitive mutants Z Li, FJ Vizeacoumar, S Bahr, J Li, J Warringer, FS Vizeacoumar, R Min, ... Nature biotechnology 29 (4), 361-367, 2011 | 326 | 2011 |
| The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast TF Menne, B Goyenechea, N Sánchez-Puig, CC Wong, LM Tonkin, ... Nature genetics 39 (4), 486-495, 2007 | 316 | 2007 |
| Systematic mapping of genetic interaction networks SJ Dixon, M Costanzo, A Baryshnikova, B Andrews, C Boone Annual review of genetics 43, 601-625, 2009 | 306 | 2009 |
| Systematic exploration of synergistic drug pairs M Cokol, HN Chua, M Tasan, B Mutlu, ZB Weinstein, Y Suzuki, ME Nergiz, ... Molecular systems biology 7 (1), 544, 2011 | 255 | 2011 |
| Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA S Leidel, PGA Pedrioli, T Bucher, R Brost, M Costanzo, A Schmidt, ... Nature 458 (7235), 228-232, 2009 | 241 | 2009 |
| Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome AJ Finch, C Hilcenko, N Basse, LF Drynan, B Goyenechea, TF Menne, ... Genes & development 25 (9), 917-929, 2011 | 235 | 2011 |
| An integrated approach to characterize genetic interaction networks in yeast metabolism B Szappanos, K Kovács, B Szamecz, F Honti, M Costanzo, ... Nature genetics 43 (7), 656-662, 2011 | 205 | 2011 |
| The interaction network of the chaperonin CCT C Dekker, PC Stirling, EA McCormack, H Filmore, A Paul, RL Brost, ... The EMBO journal 27 (13), 1827-1839, 2008 | 204 | 2008 |
| Global gene deletion analysis exploring yeast filamentous growth O Ryan, RS Shapiro, CF Kurat, D Mayhew, A Baryshnikova, B Chin, ... Science 337 (6100), 1353-1356, 2012 | 196 | 2012 |
| Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 188 | 2017 |
| Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation R Zhao, Y Kakihara, A Gribun, J Huen, G Yang, M Khanna, M Costanzo, ... The Journal of cell biology 180 (3), 563-578, 2008 | 186 | 2008 |
| Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe A Baryshnikova, M Costanzo, S Dixon, FJ Vizeacoumar, CL Myers, ... Methods in enzymology 470, 145-179, 2010 | 182 | 2010 |
| Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis DC Hess, CL Myers, C Huttenhower, MA Hibbs, AP Hayes, J Paw, ... PLoS Genet 5 (3), e1000407, 2009 | 148 | 2009 |
| Bringing order to protein disorder through comparative genomics and genetic interactions J Bellay, S Han, M Michaut, TH Kim, M Costanzo, BJ Andrews, C Boone, ... Genome biology 12 (2), 1-15, 2011 | 140 | 2011 |
Charles BooneProfessor, Donnelly Centre, University of TorontoVerified email at utoronto.ca
