| Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Z Wang, E Klipfell, BJ Bennett, R Koeth, BS Levison, B DuGar, ... nature 472 (7341), 57-63, 2011 | 5498 | 2011 |
| Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ... Nature medicine 19 (5), 576-585, 2013 | 4496 | 2013 |
| Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk WHW Tang, Z Wang, BS Levison, RA Koeth, EB Britt, X Fu, Y Wu, ... New England Journal of Medicine 368 (17), 1575-1584, 2013 | 3319 | 2013 |
| Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ... Cell 165 (1), 111-124, 2016 | 1685 | 2016 |
| Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis Z Wang, AB Roberts, JA Buffa, BS Levison, W Zhu, E Org, X Gu, Y Huang, ... Cell 163 (7), 1585-1595, 2015 | 1224 | 2015 |
| Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney … WHW Tang, Z Wang, DJ Kennedy, Y Wu, JA Buffa, B Agatisa-Boyle, XS Li, ... Circulation research 116 (3), 448-455, 2015 | 1090 | 2015 |
| Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation BJ Bennett, TQ de Aguiar Vallim, Z Wang, DM Shih, Y Meng, J Gregory, ... Cell metabolism 17 (1), 49-60, 2013 | 994 | 2013 |
| Protein carbamylation links inflammation, smoking, uremia and atherogenesis Z Wang, SJ Nicholls, ER Rodriguez, O Kummu, S Hörkkö, J Barnard, ... Nature medicine 13 (10), 1176-1184, 2007 | 787 | 2007 |
| Trimethylamine N‐oxide promotes vascular inflammation through signaling of mitogen‐activated protein kinase and nuclear factor‐κB MM Seldin, Y Meng, H Qi, WF Zhu, Z Wang, SL Hazen, AJ Lusis, DM Shih Journal of the American Heart Association 5 (2), e002767, 2016 | 741 | 2016 |
| Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis WHW Tang, Z Wang, Y Fan, B Levison, JE Hazen, LM Donahue, Y Wu, ... Journal of the American College of Cardiology 64 (18), 1908-1914, 2014 | 696 | 2014 |
| Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide Z Wang, WHW Tang, JA Buffa, X Fu, EB Britt, RA Koeth, BS Levison, ... European heart journal 35 (14), 904-910, 2014 | 598 | 2014 |
| γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ... Cell metabolism 20 (5), 799-812, 2014 | 526 | 2014 |
| Transmission of atherosclerosis susceptibility with gut microbial transplantation JC Gregory, JA Buffa, E Org, Z Wang, BS Levison, W Zhu, MA Wagner, ... Journal of Biological Chemistry 290 (9), 5647-5660, 2015 | 505 | 2015 |
| Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors XS Li, S Obeid, R Klingenberg, B Gencer, F Mach, L Räber, S Windecker, ... European heart journal 38 (11), 814-824, 2017 | 457 | 2017 |
| Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential AB Roberts, X Gu, JA Buffa, AG Hurd, Z Wang, W Zhu, N Gupta, SM Skye, ... Nature medicine 24 (9), 1407-1417, 2018 | 439 | 2018 |
| An abundant dysfunctional apolipoprotein A1 in human atheroma Y Huang, JA DiDonato, BS Levison, D Schmitt, L Li, Y Wu, J Buffa, T Kim, ... Nature medicine 20 (2), 193-203, 2014 | 398 | 2014 |
| The TMAO-generating enzyme flavin monooxygenase 3 is a central regulator of cholesterol balance M Warrier, DM Shih, AC Burrows, D Ferguson, AD Gromovsky, AL Brown, ... Cell reports 10 (3), 326-338, 2015 | 392 | 2015 |
| Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women Z Wang, N Bergeron, BS Levison, XS Li, S Chiu, X Jia, RA Koeth, L Li, ... European heart journal 40 (7), 583-594, 2019 | 387 | 2019 |
| Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure WHW Tang, Z Wang, K Shrestha, AG Borowski, Y Wu, RW Troughton, ... Journal of cardiac failure 21 (2), 91-96, 2015 | 349 | 2015 |
| Choline diet and its gut microbe–derived metabolite, trimethylamine N-oxide, exacerbate pressure overload–induced heart failure CL Organ, H Otsuka, S Bhushan, Z Wang, J Bradley, R Trivedi, ... Circulation: Heart Failure 9 (1), e002314, 2016 | 339 | 2016 |
