| Structure of the [NiFe] Hydrogenase Active Site: Evidence for Biologically Uncommon Fe Ligands⊥ A Volbeda, E Garcin, C Piras, AL de Lacey, VM Fernandez, EC Hatchikian, ... Journal of the American Chemical Society 118 (51), 12989-12996, 1996 | 818 | 1996 |
| The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center E Garcin, X Vernede, EC Hatchikian, A Volbeda, M Frey, ... Structure 7 (5), 557-566, 1999 | 589 | 1999 |
| Structural differences between the ready and unready oxidized states of [NiFe] hydrogenases A Volbeda, L Martin, C Cavazza, M Matho, BW Faber, W Roseboom, ... JBIC Journal of Biological Inorganic Chemistry 10 (3), 239-249, 2005 | 414 | 2005 |
| Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase ED Garcin, CM Bruns, SJ Lloyd, DJ Hosfield, M Tiso, R Gachhui, ... Journal of biological chemistry 279 (36), 37918-37927, 2004 | 318 | 2004 |
| Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase ED Garcin, AS Arvai, RJ Rosenfeld, MD Kroeger, BR Crane, G Andersson, ... Nature chemical biology 4 (11), 700-707, 2008 | 249 | 2008 |
| Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death GA Rameau, DS Tukey, ED Garcin-Hosfield, RF Titcombe, C Misra, ... Journal of Neuroscience 27 (13), 3445-3455, 2007 | 187 | 2007 |
| Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 Å resolution structures of the wild type and a mutant of malate dehydrogenase from … SB Richard, D Madern, E Garcin, G Zaccai Biochemistry 39 (5), 992-1000, 2000 | 132 | 2000 |
| DNA apurinic-apyrimidinic site binding and excision by endonuclease IV ED Garcin, DJ Hosfield, SA Desai, BJ Haas, M Björas, RP Cunningham, ... Nature structural & molecular biology 15 (5), 515, 2008 | 111 | 2008 |
| Hydrogenase: a hydrogen-metabolizing enzyme. What do the crystal structures tell us about its mode of action? JC Fontecilla-Camps, M Frey, E Garcin, C Hatchikian, Y Montet, C Piras, ... Biochimie 79 (11), 661-666, 1997 | 88 | 1997 |
| Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency RJ Rosenfeld, ED Garcin, K Panda, G Andersson, A Åberg, AV Wallace, ... Biochemistry 41 (47), 13915-13925, 2002 | 82 | 2002 |
| Surface charge interactions of the FMN module govern catalysis by nitric-oxide synthase K Panda, MM Haque, ED Garcin-Hosfield, D Durra, ED Getzoff, DJ Stuehr Journal of Biological Chemistry 281 (48), 36819-36827, 2006 | 67 | 2006 |
| The three nitric-oxide synthases differ in their kinetics of tetrahydrobiopterin radical formation, heme-dioxy reduction, and arginine hydroxylation CC Wei, ZQ Wang, D Durra, C Hemann, R Hille, ED Garcin, ED Getzoff, ... Journal of Biological Chemistry 280 (10), 8929-8935, 2005 | 62 | 2005 |
| D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and Function MR White, ED Garcin Macromolecular Protein Complexes, 413-453, 2017 | 61 | 2017 |
| A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA MR White, MM Khan, D Deredge, CR Ross, R Quintyn, BE Zucconi, ... Journal of Biological Chemistry 290 (3), 1770-1785, 2015 | 57 | 2015 |
| C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase M Tiso, DW Konas, K Panda, ED Garcin, M Sharma, ED Getzoff, ... Journal of Biological Chemistry 280 (47), 39208-39219, 2005 | 49 | 2005 |
| GAPDH as a model non-canonical AU-rich RNA binding protein ED Garcin Seminars in cell & developmental biology 86, 162-173, 2019 | 48 | 2019 |
| The sweet side of RNA regulation: glyceraldehyde‐3‐phosphate dehydrogenase as a noncanonical RNA‐binding protein MR White, ED Garcin Wiley Interdisciplinary Reviews: RNA 7 (1), 53-70, 2016 | 48 | 2016 |
| Small-angle X-ray scattering method to characterize molecular interactions: Proof of concept N Allec, M Choi, N Yesupriya, B Szychowski, MR White, MG Kann, ... Scientific reports 5 (1), 1-12, 2015 | 48 | 2015 |
| Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity F Seeger, R Quintyn, A Tanimoto, GJ Williams, JA Tainer, VH Wysocki, ... Biochemistry 53 (13), 2153-2165, 2014 | 47 | 2014 |
| YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit R Purohit, BG Fritz, J The, A Issaian, A Weichsel, CL David, E Campbell, ... Biochemistry 53 (1), 101-114, 2014 | 43 | 2014 |
dennis stuehrThe Cleveland ClinicVerified email at ccf.org
