Surya Reis
Surya Reis
Center for Human Genetic Research, Massachusetts General Hospital, HMS
Verified email at
TitleCited byYear
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses
F Zalfa, M Giorgi, B Primerano, A Moro, A Di Penta, S Reis, B Oostra, ...
Cell 112 (3), 317-327, 2003
The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome
R Willemsen, M Hoogeveen-Westerveld, S Reis, J Holstege, ...
Human molecular genetics 12 (9), 949-959, 2003
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome
SD Sheridan, KM Theriault, SA Reis, F Zhou, JM Madison, L Daheron, ...
PloS one 6 (10), 2011
An aldol-based build/couple/pair strategy for the synthesis of medium-and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors
LA Marcaurelle, E Comer, S Dandapani, JR Duvall, B Gerard, S Kesavan, ...
Journal of the American Chemical Society 132 (47), 16962-16976, 2010
Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo
EJ Mientjes, R Willemsen, LL Kirkpatrick, IM Nieuwenhuizen, ...
Human molecular genetics 13 (13), 1291-1302, 2004
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests
FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ...
PloS one 8 (8), 2013
Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity
DM Fass, SA Reis, B Ghosh, KM Hennig, NF Joseph, WN Zhao, ...
Neuropharmacology 64, 81-96, 2013
Monoalkoxy BODIPYs A Fluorophore Class for Bioimaging
AM Courtis, SA Santos, Y Guan, JA Hendricks, B Ghosh, DM Szantai-Kis, ...
Bioconjugate chemistry 25 (6), 1043-1051, 2014
Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers
FF Wagner, YL Zhang, DM Fass, N Joseph, JP Gale, M We´wer, ...
Chemical science 6 (1), 804-815, 2015
In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs
C Wang, FA Schroeder, HY Wey, R Borra, FF Wagner, S Reis, SW Kim, ...
Journal of medicinal chemistry 57 (19), 7999-8009, 2014
Light-controlled modulation of gene expression by chemical optoepigenetic probes
SA Reis, B Ghosh, JA Hendricks, DM Szantai-Kis, L T÷rk, KN Ross, ...
Nature chemical biology 12 (5), 317, 2016
Short-chain HDAC inhibitors differentially affect vertebrate development and neuronal chromatin
DM Fass, R Shah, B Ghosh, K Hennig, S Norton, WN Zhao, SA Reis, ...
ACS Medicinal Chemistry Letters 2 (1), 39-42, 2011
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
DM Fass, R Shah, B Ghosh, K Hennig, S Norton, WN Zhao, SA Reis, ...
ACS medicinal chemistry letters 2 (1), 39-42, 2010
Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells
M Schrier, LA Severijnen, S Reis, M Rife, S van't Padje, G van Cappellen, ...
Experimental neurology 189 (2), 343-353, 2004
Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis
SA Reis, MN Thompson, JM Lee, E Fossale, HH Kim, JK Liao, ...
Human molecular genetics 20 (12), 2344-2355, 2011
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors
FF Wagner, M We´wer, S Steinbacher, A Schomburg, P Reinemer, ...
Bioorganic & medicinal chemistry 24 (18), 4008-4015, 2016
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat
FA Schroeder, C Wang, GC Van de Bittner, R Neelamegam, ...
ACS chemical neuroscience 5 (10), 1055-1062, 2014
Selectivity and kinetic requirements of HDAC inhibitors as progranulin enhancers for treating frontotemporal dementia
A She, I Kurtser, SA Reis, K Hennig, J Lai, A Lang, WN Zhao, ...
Cell chemical biology 24 (7), 892-906. e5, 2017
Prospects of TAT-mediated protein therapy for fragile X syndrome
SA Reis, R Willemsen, L van Unen, AT Hoogeveen, BA Oostra
Journal of molecular histology 35 (4), 389-395, 2004
Dissecting structure–activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation
B Ghosh, WN Zhao, SA Reis, D Patnaik, DM Fass, LH Tsai, R Mazitschek, ...
Bioorganic & medicinal chemistry letters 26 (4), 1265-1271, 2016
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