עקוב אחר
William R. Sellers
William R. Sellers
Core Institute Member, The Broad Institute
כתובת אימייל מאומתת בדומיין broadinstitute.org
כותרת
צוטט על ידי
צוטט על ידי
שנה
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ...
Science 304 (5676), 1497-1500, 2004
119392004
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
77162012
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
41902010
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
38192005
Gene expression correlates of clinical prostate cancer behavior
D Singh, PG Febbo, K Ross, DG Jackson, J Manola, C Ladd, P Tamayo, ...
Cancer cell 1 (2), 203-209, 2002
31172002
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
23752019
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
LA Garraway, HR Widlund, MA Rubin, G Getz, AJ Berger, S Ramaswamy, ...
Nature 436 (7047), 117-122, 2005
17832005
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
17192005
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17132010
Molecular characterization of the tumor microenvironment in breast cancer
M Allinen, R Beroukhim, L Cai, C Brennan, J Lahti-Domenici, H Huang, ...
Cancer cell 6 (1), 17-32, 2004
15732004
BRAF mutation predicts sensitivity to MEK inhibition
DB Solit, LA Garraway, CA Pratilas, A Sawai, G Getz, A Basso, Q Ye, ...
Nature 439 (7074), 358-362, 2006
15362006
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo …
SM Maira, F Stauffer, J Brueggen, P Furet, C Schnell, C Fritsch, ...
Molecular cancer therapeutics 7 (7), 1851-1863, 2008
13492008
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
H Gao, JM Korn, S Ferretti, JE Monahan, Y Wang, M Singh, C Zhang, ...
Nature medicine 21 (11), 1318-1325, 2015
13092015
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
I Sansal, WR Sellers
Journal of clinical oncology 22 (14), 2954-2963, 2004
12452004
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12352007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11602007
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
PK Majumder, PG Febbo, R Bikoff, R Berger, Q Xue, LM McMahon, ...
Nature medicine 10 (6), 594-601, 2004
11382004
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
WG Kaelin Jr, W Krek, WR Sellers, JA DeCaprio, F Ajchenbaum, ...
Cell 70 (2), 351-364, 1992
10601992
Phosphorylation of the PTEN tail regulates protein stability and function
F Vazquez, S Ramaswamy, N Nakamura, WR Sellers
Molecular and cellular biology 20 (14), 5010-5018, 2000
9462000
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
ME McMenamin, P Soung, S Perera, I Kaplan, M Loda, WR Sellers
Cancer research 59 (17), 4291-4296, 1999
9201999
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20