| Folding of the adenine riboswitch JF Lemay, JC Penedo, R Tremblay, DMJ Lilley, DA Lafontaine Chemistry & biology 13 (8), 857-868, 2006 | 337 | 2006 |
| Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways J Mulhbacher, E Brouillette, M Allard, LC Fortier, F Malouin, ... PLoS pathogens 6 (4), e1000865, 2010 | 202 | 2010 |
| Dual-acting riboswitch control of translation initiation and mRNA decay MP Caron, L Bastet, A Lussier, M Simoneau-Roy, E Massé, DA Lafontaine Proceedings of the National Academy of Sciences 109 (50), E3444-E3453, 2012 | 199 | 2012 |
| Comparative study between transcriptionally-and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms JF Lemay, G Desnoyers, S Blouin, B Heppell, L Bastet, P St-Pierre, ... PLoS genetics 7 (1), e1001278, 2011 | 197 | 2011 |
| Regulatory RNAs and target mRNA decay in prokaryotes D Lalaouna, M Simoneau-Roy, D Lafontaine, E Massé Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013 | 163 | 2013 |
| Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile E Bordeleau, EB Purcell, DA Lafontaine, LC Fortier, R Tamayo, V Burrus Journal of bacteriology 197 (5), 819-832, 2015 | 153 | 2015 |
| Therapeutic applications of ribozymes and riboswitches J Mulhbacher, P St-Pierre, DA Lafontaine Current opinion in pharmacology 10 (5), 551-556, 2010 | 137 | 2010 |
| Molecular insights into the ligand-controlled organization of the SAM-I riboswitch B Heppell, S Blouin, AM Dussault, J Mulhbacher, E Ennifar, JC Penedo, ... Nature chemical biology 7 (6), 384-392, 2011 | 127 | 2011 |
| Ligand recognition determinants of guanine riboswitches J Mulhbacher, DA Lafontaine Nucleic acids research 35 (16), 5568-5580, 2007 | 122 | 2007 |
| Structure, folding and activity of the VS ribozyme: importance of the 2‐3‐6 helical junction DA Lafontaine, DG Norman, DMJ Lilley The EMBO Journal, 2001 | 117 | 2001 |
| The global structure of the VS ribozyme DA Lafontaine, DG Norman, DMJ Lilley The EMBO journal 21 (10), 2461-2471, 2002 | 115 | 2002 |
| Small RNA-mediated regulation at the level of transcript stability MP Caron, DA Lafontaine, E Massé RNA biology 7 (2), 140-144, 2010 | 113 | 2010 |
| New insights into riboswitch regulation mechanisms L Bastet, A Dubé, E Massé, DA Lafontaine Molecular microbiology 80 (5), 1148-1154, 2011 | 111 | 2011 |
| Riboswitches: ancient and promising genetic regulators S Blouin, J Mulhbacher, JC Penedo, DA Lafontaine ChemBioChem 10 (3), 400-416, 2009 | 100 | 2009 |
| A loop–loop interaction and a K-turn motif located in the lysine aptamer domain are important for the riboswitch gene regulation control S Blouin, DA Lafontaine Rna 13 (8), 1256-1267, 2007 | 99 | 2007 |
| Folding of the SAM aptamer is determined by the formation of a K-turn-dependent pseudoknot B Heppell, DA Lafontaine Biochemistry 47 (6), 1490-1499, 2008 | 94 | 2008 |
| Core requirements of the adenine riboswitch aptamer for ligand binding JF Lemay, DA Lafontaine Rna 13 (3), 339-350, 2007 | 93 | 2007 |
| Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation A Chauvier, F Picard-Jean, JC Berger-Dancause, L Bastet, MR Naghdi, ... Nature communications 8 (1), 13892, 2017 | 89 | 2017 |
| The A730 loop is an important component of the active site of the VS ribozyme DA Lafontaine, TJ Wilson, DG Norman, DMJ Lilley Journal of molecular biology 312 (4), 663-674, 2001 | 88 | 2001 |
| Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation L Bastet, A Chauvier, N Singh, A Lussier, AM Lamontagne, K Prévost, ... Nucleic acids research 45 (12), 7474-7486, 2017 | 82 | 2017 |
Carlos PenedoProfessor of Physics and Biology, Director Centre of Biophotonics, St AndrewsVerified email at st-andrews.ac.uk
