| Cell death mechanisms in eukaryotes JG Nirmala, M Lopus Cell biology and toxicology 36 (2), 145-164, 2020 | 261 | 2020 |
| Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules M Lopus, E Oroudjev, L Wilson, S Wilhelm, W Widdison, R Chari, ... Molecular cancer therapeutics 9 (10), 2689-2699, 2010 | 225 | 2010 |
| Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability E Oroudjev, M Lopus, L Wilson, C Audette, C Provenzano, H Erickson, ... Molecular cancer therapeutics 9 (10), 2700-2713, 2010 | 194 | 2010 |
| Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death R Aneja, SN Vangapandu, M Lopus, VG Viswesarappa, N Dhiman, ... Biochemical pharmacology 72 (4), 415-426, 2006 | 111 | 2006 |
| Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma R Aneja, SN Vangapandu, M Lopus, R Chandra, D Panda, HC Joshi Molecular pharmacology 69 (6), 1801-1809, 2006 | 110 | 2006 |
| The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding: a possible mechanism for its antiproliferative activity M Lopus, D Panda The FEBS journal 273 (10), 2139-2150, 2006 | 101 | 2006 |
| Antibody-DM1 conjugates as cancer therapeutics M Lopus Cancer letters 307 (2), 113-118, 2011 | 100 | 2011 |
| Rational design of the microtubule-targeting anti–breast cancer drug EM015 R Aneja, M Lopus, J Zhou, SN Vangapandu, A Ghaleb, J Yao, JH Nettles, ... Cancer research 66 (7), 3782-3791, 2006 | 71 | 2006 |
| Second generation benzofuranone ring substituted noscapine analogs: synthesis and biological evaluation RC Mishra, P Karna, SR Gundala, V Pannu, RA Stanton, KK Gupta, ... Biochemical pharmacology 82 (2), 110-121, 2011 | 68 | 2011 |
| Rational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agents NK Manchukonda, PK Naik, S Santoshi, M Lopus, S Joseph, B Sridhar, ... PLoS one 8 (10), e77970, 2013 | 64 | 2013 |
| The spontaneous remission of cancer: Current insights and therapeutic significance G Radha, M Lopus Translational oncology 14 (9), 101166, 2021 | 49 | 2021 |
| Mechanism of action of ixabepilone and its interactions with the βIII-tubulin isotype M Lopus, G Smiyun, H Miller, E Oroudjev, L Wilson, MA Jordan Cancer chemotherapy and pharmacology 76, 1013-1024, 2015 | 44 | 2015 |
| Biochemical characterization and molecular dynamic simulation of β-sitosterol as a tubulin-binding anticancer agent T Mahaddalkar, C Suri, PK Naik, M Lopus European journal of pharmacology 760, 154-162, 2015 | 43 | 2015 |
| Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents S Santoshi, NK Manchukonda, C Suri, M Sharma, B Sridhar, S Joseph, ... Journal of computer-aided molecular design 29, 249-270, 2015 | 42 | 2015 |
| In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin) PK Naik, M Lopus, R Aneja, SN Vangapandu, HC Joshi Journal of computer-aided molecular design 26, 233-247, 2012 | 41 | 2012 |
| Chemical characteristics, antioxidant and anticancer potential of sulfated polysaccharides from Chlamydomonas reinhardtii P Kamble, S Cheriyamundath, M Lopus, VL Sirisha Journal of applied phycology 30, 1641-1653, 2018 | 39 | 2018 |
| The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation AL Risinger, SM Riffle, M Lopus, MA Jordan, L Wilson, SL Mooberry Molecular cancer 13, 1-12, 2014 | 39 | 2014 |
| Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach V Pannu, PCG Rida, A Ogden, R Clewley, A Cheng, P Karna, M Lopus, ... Cell death & disease 3 (7), e346-e346, 2012 | 38 | 2012 |
| Taking aim at a dynamic target: Noscapinoids as microtubule-targeted cancer therapeutics M Lopus, PK Naik Pharmacological Reports 67, 56-62, 2015 | 36 | 2015 |
| Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations T Mahaddalkar, PK Naik, S Choudhary, N Manchukonda, S Kantevari, ... Journal of Biomolecular Structure and Dynamics 35 (11), 2475-2484, 2017 | 34 | 2017 |
Ritu AnejaProfessor of Cancer Biology, University of Alabama at BirminghamVerified email at uab.edu
