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James Earnest
James Earnest
Postdoctoral Researcher, Emory University
No verified email
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Year
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ...
Nature immunology 21 (11), 1327-1335, 2020
4352020
Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice
K Li, CL Wohlford-Lenane, R Channappanavar, JE Park, JT Earnest, ...
Proceedings of the National Academy of Sciences 114 (15), E3119-E3128, 2017
1322017
The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
JT Earnest, MP Hantak, K Li, PB McCray Jr, S Perlman, T Gallagher
PLoS pathogens 13 (7), e1006546, 2017
1002017
Tetraspanins: architects of viral entry and exit platforms
MP Hantak, E Qing, JT Earnest, T Gallagher
Journal of virology 93 (6), e01429-17, 2019
562019
Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomains
JT Earnest, MP Hantak, JE Park, T Gallagher
Journal of virology 89 (11), 6093-6104, 2015
492015
Expression of the Mxra8 receptor promotes alphavirus infection and pathogenesis in mice and drosophila
R Zhang, JT Earnest, AS Kim, ES Winkler, P Desai, LJ Adams, G Hu, ...
Cell reports 28 (10), 2647-2658. e5, 2019
322019
Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity
JT Earnest, K Basore, V Roy, AL Bailey, D Wang, G Alter, DH Fremont, ...
Journal of Experimental Medicine 216 (10), 2282-2301, 2019
292019
LDLRAD3 is a receptor for Venezuelan equine encephalitis virus
H Ma, AS Kim, NM Kafai, JT Earnest, AP Shah, JB Case, K Basore, ...
Nature 588 (7837), 308-314, 2020
282020
SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function
ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ...
BioRxiv, 2020
232020
Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ...
Nature immunology, 1, 2020
162020
Structural basis of Chikungunya virus inhibition by monoclonal antibodies
QF Zhou, JM Fox, JT Earnest, TS Ng, AS Kim, G Fibriansah, ...
Proceedings of the National Academy of Sciences 117 (44), 27637-27645, 2020
142020
The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies
JT Earnest, AC Holmes, K Basore, M Mack, DH Fremont, MS Diamond
Cell reports 35 (1), 108962, 2021
112021
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope
AS Kim, NM Kafai, ES Winkler, TC Gilliland Jr, EL Cottle, JT Earnest, ...
Cell 184 (17), 4414-4429. e19, 2021
102021
Structural characterization of broadly neutralizing alphavirus antibodies
K Basore, JT Earnest, MS Diamond, DH Fremont
The Journal of Immunology 200 (1 Supplement), 126.33-126.33, 2018
22018
Bates 574 AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB, Jr. 575 2017. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 …
K Li, CL Wohlford-Lenane, R Channappanavar, JE Park, JT Earnest, ...
Proc Natl Acad Sci USA 114, E3119-E3128, 0
2
Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses
RJ Malonis, JT Earnest, AS Kim, M Angeliadis, FW Holtsberg, MJ Aman, ...
Proceedings of the National Academy of Sciences 118 (37), 2021
12021
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function (vol 51, pg 831, 2020)
ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune, J Yu, JM Fox, ...
NATURE IMMUNOLOGY 21 (11), 1470-1470, 2020
12020
SARS-CoV-2 Antibody Prevalence in a Pediatric Cohort of Unvaccinated Children in Mérida, Yucatán, México
GA Talavera, OD Kirstein, H Puerta-Guardo, GA Barrera-Fuentes, ...
2021
Cellular Determinants of Coronavirus Entry Routes
JT Earnest
2017
Corona and Influenza Virus Proteolytic Priming takes place in Tetraspanin-Enriched
JT Earnest, MP Hantak, JE Park, T Gallagher
Virology journal 6 (76), 713, 2015
2015
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