| Intravenous lidocaine speeds the return of bowel function, decreases postoperative pain, and shortens hospital stay in patients undergoing radical retropubic prostatectomy SB Groudine, HAG Fisher, RP Kaufman, MK Patel, LJ Wilkins, SA Mehta, ... Anesthesia & Analgesia 86 (2), 235-239, 1998 | 502 | 1998 |
| Genetically targeted magnetic control of the nervous system MA Wheeler, CJ Smith, M Ottolini, BS Barker, AM Purohit, RM Grippo, ... Nature neuroscience 19 (5), 756-761, 2016 | 268 | 2016 |
| Subtype-selective small molecule inhibitors reveal a fundamental role for Nav1. 7 in nociceptor electrogenesis, axonal conduction and presynaptic release AJ Alexandrou, AR Brown, ML Chapman, M Estacion, J Turner, MA Mis, ... PloS one 11 (4), e0152405, 2016 | 171 | 2016 |
| The sodium channel β-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart AI Fahmi, M Patel, EB Stevens, AL Fowden, JE John III, K Lee, R Pinnock, ... The Journal of physiology 537 (Pt 3), 693, 2001 | 154 | 2001 |
| SCN8A encephalopathy: Research progress and prospects MH Meisler, G Helman, MF Hammer, BE Fureman, WD Gaillard, ... Epilepsia 57 (7), 1027-1035, 2016 | 124 | 2016 |
| Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesis NJ Hargus, A Nigam, EH Bertram III, MK Patel Journal of neurophysiology 110 (5), 1144-1157, 2013 | 120 | 2013 |
| Gabapentin inhibits excitatory synaptic transmission in the hyperalgesic spinal cord MK Patel, MI Gonzalez, S Bramwell, RD Pinnock, K Lee British journal of pharmacology 130 (8), 1731-1734, 2000 | 116 | 2000 |
| Design, synthesis and evaluation of novel hydroxyamides as orally available anticonvulsants HA Schenck, PW Lenkowski, I Choudhury-Mukherjee, SH Ko, JP Stables, ... Bioorganic & medicinal chemistry 12 (5), 979-993, 2004 | 111 | 2004 |
| Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy JL Wagnon, BS Barker, JA Hounshell, CA Haaxma, A Shealy, T Moss, ... Annals of clinical and translational neurology 3 (2), 114-123, 2016 | 106 | 2016 |
| Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight RP Gaykema, BA Newmyer, M Ottolini, V Raje, DM Warthen, PS Lambeth, ... The Journal of clinical investigation 127 (3), 1031-1045, 2017 | 101 | 2017 |
| CaV3.2 is the major molecular substrate for redox regulation of T‐type Ca2+ channels in the rat and mouse thalamus PM Joksovic, MT Nelson, V Jevtovic‐Todorovic, MK Patel, E Perez‐Reyes, ... The Journal of physiology 574 (2), 415-430, 2006 | 99 | 2006 |
| Modulation of Nav1.5 by β1- and β3-subunit co-expression in mammalian cells SH Ko, PW Lenkowski, HC Lee, JP Mounsey, MK Patel Pflügers Archiv 449, 403-412, 2005 | 98 | 2005 |
| Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons NJ Hargus, EC Merrick, A Nigam, CL Kalmar, AR Baheti, EH Bertram III, ... Neurobiology of disease 41 (2), 361-376, 2011 | 82 | 2011 |
| Voltage-gated sodium channel blockers as cytostatic inhibitors of the androgen-independent prostate cancer cell line PC-3 JD Anderson, TP Hansen, PW Lenkowski, AM Walls, IM Choudhury, ... Molecular cancer therapeutics 2 (11), 1149-1154, 2003 | 76 | 2003 |
| Prominent role of forebrain excitatory neurons in SCN8A encephalopathy RKA Bunton-Stasyshyn, JL Wagnon, ER Wengert, BS Barker, A Faulkner, ... Brain 142 (2), 362-375, 2019 | 75 | 2019 |
| Loss-of-function variants of SCN8A in intellectual disability without seizures JL Wagnon, BS Barker, M Ottolini, Y Park, A Volkheimer, P Valdez, ... Neurology: Genetics 3 (4), e170, 2017 | 73 | 2017 |
| Adenosine exerts multiple effects in dorsal horn neurones of the adult rat spinal cord MK Patel, RD Pinnock, K Lee Brain research 920 (1-2), 19-26, 2001 | 67 | 2001 |
| The novel sodium channel modulator GS‐458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy EM Baker, CH Thompson, NA Hawkins, JL Wagnon, ER Wengert, ... Epilepsia 59 (6), 1166-1176, 2018 | 60 | 2018 |
| The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin BS Barker, M Ottolini, JL Wagnon, RM Hollander, MH Meisler, MK Patel Epilepsia 57 (9), 1458-1466, 2016 | 56 | 2016 |
| Lidocaine block of neonatal Nav1. 3 is differentially modulated by co-expression of β1 and β3 subunits PW Lenkowski, BS Shah, AE Dinn, K Lee, MK Patel European journal of pharmacology 467 (1-3), 23-30, 2003 | 53 | 2003 |
