Lis1 is an initiation factor for dynein-driven organelle transport MJ Egan, K Tan, SL Reck-Peterson Journal of Cell Biology 197 (7), 971-982, 2012 | 208 | 2012 |
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans MD Leach, RA Farrer, K Tan, Z Miao, LA Walker, CA Cuomo, RT Wheeler, ... Nature communications 7 (1), 11704, 2016 | 113 | 2016 |
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation K Miao, JH Lei, MV Valecha, A Zhang, J Xu, L Wang, X Lyu, S Chen, ... Nature communications 11 (1), 3256, 2020 | 88 | 2020 |
Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 GCG Choi, P Zhou, CTL Yuen, BKC Chan, F Xu, S Bao, HY Chu, D Thean, ... Nature methods 16 (8), 722-730, 2019 | 76 | 2019 |
Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments F Wang, P Sethiya, X Hu, S Guo, Y Chen, A Li, K Tan, KH Wong Nature microbiology 6 (8), 1066-1081, 2021 | 65 | 2021 |
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation JL Xie, L Qin, Z Miao, BT Grys, JDLC Diaz, K Ting, JR Krieger, J Tong, ... Nature communications 8 (1), 499, 2017 | 62 | 2017 |
Characterization of the Mutagenic Spectrum of 4-Nitroquinoline 1-Oxide (4-NQO) in Aspergillus nidulans by Whole Genome Sequencing DJ Downes, M Chonofsky, K Tan, BT Pfannenstiel, SL Reck-Peterson, ... G3: Genes, Genomes, Genetics 4 (12), 2483-2492, 2014 | 62 | 2014 |
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ... PLoS genetics 14 (3), e1007270, 2018 | 53 | 2018 |
Carbon catabolite repression in filamentous fungi is regulated by phosphorylation of the transcription factor CreA LJ de Assis, LP Silva, O Bayram, P Dowling, O Kniemeyer, T Krüger, ... MBio 12 (1), 10.1128/mbio. 03146-20, 2021 | 49 | 2021 |
Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport J Zhang, K Tan, X Wu, G Chen, J Sun, SL Reck-Peterson, JA Hammer III, ... PloS one 6 (12), e28575, 2011 | 48 | 2011 |
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics J Lyu, EJ Yang, B Zhang, C Wu, L Pardeshi, C Shi, PK Mou, Y Liu, K Tan, ... Nature communications 11 (1), 5105, 2020 | 47 | 2020 |
SCFCdc4-mediated Degradation of the Hac1p Transcription Factor Regulates the Unfolded Protein Response in Saccharomyces cerevisiae B Pal, NC Chan, L Helfenbaum, K Tan, WP Tansey, MJ Gething Molecular biology of the cell 18 (2), 426-440, 2007 | 46 | 2007 |
A three-way combinatorial CRISPR screen for analyzing interactions among druggable targets P Zhou, BKC Chan, YK Wan, CTL Yuen, GCG Choi, X Li, CSW Tong, ... Cell reports 32 (6), 2020 | 43 | 2020 |
A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity K Tan, AJ Roberts, M Chonofsky, MJ Egan, SL Reck-Peterson Molecular biology of the cell 25 (5), 669-678, 2014 | 38 | 2014 |
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor J Liu, R Adhav, K Miao, SM Su, L Mo, UI Chan, X Zhang, J Xu, J Li, X Shu, ... Nature communications 11 (1), 4875, 2020 | 32 | 2020 |
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells B Zhang, J Lyu, EJ Yang, Y Liu, C Wu, L Pardeshi, K Tan, Q Chen, X Xu, ... Acta Pharmaceutica Sinica B 10 (4), 615-627, 2020 | 32 | 2020 |
Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg … CJIN OON, WN Chen, KT Goh, S Mesenas, HS Ng, G Chiang, C Tan, ... Journal of gastroenterology and hepatology 17, S491-S496, 2002 | 31 | 2002 |
The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence LNA Ries, L Pardeshi, Z Dong, K Tan, JL Steenwyk, AC Colabardini, ... PLoS pathogens 16 (7), e1008645, 2020 | 30 | 2020 |
PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A Y Liu, EJ Yang, B Zhang, Z Miao, C Wu, J Lyu, K Tan, TCW Poon, JS Shim Cancer letters 436, 28-37, 2018 | 20 | 2018 |
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition B Zhang, J Lyu, Y Liu, C Wu, EJ Yang, L Pardeshi, K Tan, KH Wong, ... Oncogene 37 (49), 6341-6356, 2018 | 19 | 2018 |