Serena Rinaldo
Serena Rinaldo
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NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR
G Giardina, S Rinaldo, KA Johnson, A Di Matteo, M Brunori, F Cutruzzolà
Journal of molecular biology 378 (5), 1002-1015, 2008
Glucose metabolism in the progression of prostate cancer
F Cutruzzolà, G Giardina, M Marani, A Macone, A Paiardini, S Rinaldo, ...
Frontiers in physiology 8, 97, 2017
SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
A Paone, M Marani, A Fiascarelli, S Rinaldo, G Giardina, R Contestabile, ...
Cell death & disease 5 (11), e1525-e1525, 2014
How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ...
The FEBS journal 282 (7), 1225-1241, 2015
The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli
N Castiglione, S Rinaldo, G Giardina, F Cutruzzola
Microbiology 155 (9), 2838-2844, 2009
Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease
N Castiglione, S Rinaldo, G Giardina, V Stelitano, F Cutruzzola
Antioxidants & redox signaling 17 (4), 684-716, 2012
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
F Daidone, R Florio, S Rinaldo, R Contestabile, ML di Salvo, F Cutruzzolà, ...
European journal of medicinal chemistry 46 (5), 1616-1621, 2011
The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
D Antoniani, E Rossi, S Rinaldo, P Bocci, M Lolicato, A Paiardini, ...
Applied microbiology and biotechnology 97 (16), 7325-7336, 2013
C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG
V Stelitano, G Giardina, A Paiardini, N Castiglione, F Cutruzzolà, ...
PLoS One 8 (9), e74920, 2013
Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy
V Stelitano, A Brandt, S Fernicola, S Franceschini, G Giardina, A Pica, ...
Nucleic acids research 41 (7), e79-e79, 2013
Nitrite reductases in denitrification
S Rinaldo, F Cutruzzolà
Biology of the nitrogen cycle, 37-55, 2007
Fast dissociation of nitric oxide from ferrous Pseudomonas aeruginosa cd1 nitrite reductase: A novel outlook on the catalytic mechanism
S Rinaldo, A Arcovito, M Brunori, F Cutruzzolà
Journal of Biological Chemistry 282 (20), 14761-14767, 2007
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells
M Marani, A Paone, A Fiascarelli, A Macone, M Gargano, S Rinaldo, ...
Oncotarget 7 (4), 4570, 2016
Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain
G Giardina, A Paiardini, S Fernicola, S Franceschini, S Rinaldo, ...
PloS one 8 (11), e81324, 2013
A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild‐type DNR
G Giardina, S Rinaldo, N Castiglione, M Caruso, F Cutruzzola
Proteins: Structure, Function, and Bioinformatics 77 (1), 174-180, 2009
In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD
S Fernicola, A Paiardini, G Giardina, G Rampioni, L Leoni, F Cutruzzolà, ...
Journal of bacteriology 198 (1), 147-156, 2015
Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site
S Rinaldo, A Paiardini, V Stelitano, P Brunotti, L Cervoni, S Fernicola, ...
Journal of bacteriology 197 (8), 1525-1535, 2015
Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase
A Paiardini, A Fiascarelli, S Rinaldo, F Daidone, G Giardina, DR Koes, ...
ChemMedChem 10 (3), 490, 2015
Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms
S Rinaldo, G Giardina, F Mantoni, A Paone, F Cutruzzolà
FEMS microbiology letters 365 (6), fny029, 2018
Synthesis of triazole-linked analogues of c-di-GMP and their interactions with diguanylate cyclase
S Fernicola, I Torquati, A Paiardini, G Giardina, G Rampioni, M Messina, ...
Journal of medicinal chemistry 58 (20), 8269-8284, 2015
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