Benjamin H. Rotstein
Benjamin H. Rotstein
University of Ottawa & University of Ottawa Heart Institute
Verified email at uottawa.ca - Homepage
TitleCited byYear
Small heterocycles in multicomponent reactions
BH Rotstein, S Zaretsky, V Rai, AK Yudin
Chemical Reviews 114 (16), 8323-8359, 2014
4552014
Spirocyclic hypervalent iodine (III)-mediated radiofluorination of non-activated and hindered aromatics
BH Rotstein, NA Stephenson, N Vasdev, SH Liang
Nature Communications 5, 4365, 2014
1342014
Method of fluorination using iodonium ylides
N Vasdev, BH Rotstein, HS Liang
US Patent 10,259,800, 2019
712019
11CO2 fixation: a renaissance in PET radiochemistry
BH Rotstein, SH Liang, JP Holland, TL Collier, JM Hooker, AA Wilson, ...
Chemical Communications 49 (50), 5621-5629, 2013
532013
Mechanistic Studies and Radiofluorination of Structurally Diverse Pharmaceuticals with Spirocyclic Iodonium(III) Ylides
B Rotstein, L Wang, R Liu, E Kwan, N Vasdev, SH Liang
Chemical Science 7 (7), 4407-4417, 2016
502016
Synthesis of peptide macrocycles using unprotected amino aldehydes
BH Rotstein, V Rai, R Hili, AK Yudin
Nature Protocols 5 (11), 1813-1822, 2010
492010
11C═O bonds made easily for positron emission tomography radiopharmaceuticals
BH Rotstein, SH Liang, MS Placzek, JM Hooker, AD Gee, F Dollé, ...
Chemical Society Reviews 45 (17), 4708-4726, 2016
442016
Ortho‐Stabilized 18F‐Azido Click Agents and their Application in PET Imaging with Single‐Stranded DNA Aptamers
L Wang, O Jacobson, D Avdic, BH Rotstein, ID Weiss, L Collier, X Chen, ...
Angewandte Chemie International Edition 54 (43), 12777-12781, 2015
432015
Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque
JP Holland, SH Liang, BH Rotstein, TL Collier, NA Stephenson, I Greguric, ...
Journal of Labelled Compounds and Radiopharmaceuticals 57 (4), 323-331, 2014
402014
Solvatochromic Reagents for Multicomponent Reactions and their Utility in the Development of Cell‐Permeable Macrocyclic Peptide Vectors
BH Rotstein, R Mourtada, SO Kelley, AK Yudin
Chemistry–A European Journal 17 (44), 12257-12261, 2011
382011
Thioester-isocyanides: versatile reagents for the synthesis of cycle–tail peptides
BH Rotstein, DJ Winternheimer, LM Yin, CM Deber, AK Yudin
Chemical Communications 48 (31), 3775-3777, 2012
332012
Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry
A Roxin, J Chen, CCG Scully, BH Rotstein, AK Yudin, G Zheng
Bioconjugate chemistry 23 (7), 1387-1395, 2012
312012
Rapid microfluidic flow hydrogenation for reduction or deprotection of 18F-labeled compounds
SH Liang, TL Collier, BH Rotstein, R Lewis, M Steck, N Vasdev
Chemical Communications 49 (78), 8755-8757, 2013
292013
Synthesis of [11C]Bexarotene by Cu-Mediated [11C]Carbon Dioxide Fixation and Preliminary PET Imaging
BH Rotstein, JM Hooker, J Woo, TL Collier, TJ Brady, SH Liang, N Vasdev
ACS medicinal chemistry letters 5 (6), 668-672, 2014
262014
Synthesis and preclinical evaluation of sulfonamido-based [11C-Carbonyl]-carbamates and ureas for imaging monoacylglycerol lipase
L Wang, W Mori, R Cheng, J Yui, A Hatori, L Ma, Y Zhang, BH Rotstein, ...
Theranostics 6 (8), 1145, 2016
212016
Stereocontrolled disruption of the Ugi reaction toward the production of chiral piperazinones: substrate scope and process development
S Zaretsky, S Adachi, BH Rotstein, JL Hickey, CCG Scully, JD St. Denis, ...
The Journal of organic chemistry 79 (21), 9948-9957, 2014
192014
Shifting the energy landscape of multicomponent reactions using aziridine aldehyde dimers: a mechanistic study
L Belding, S Zaretsky, BH Rotstein, AK Yudin, T Dudding
The Journal of organic chemistry 79 (20), 9465-9471, 2014
182014
Comparison of benzene, nitrobenzene, and dinitrobenzene 2-arylsulfenylpyrroles
JR Garabatos-Perera, BH Rotstein, A Thompson
The Journal of organic chemistry 72 (19), 7382-7385, 2007
182007
PET neuroimaging studies of [18F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and nonhuman primates
SH Liang, JP Holland, NA Stephenson, A Kassenbrock, BH Rotstein, ...
ACS chemical neuroscience 6 (4), 535-541, 2015
132015
PET imaging of fatty acid amide hydrolase with [18F]DOPP in nonhuman primates
BH Rotstein, HY Wey, TM Shoup, AA Wilson, SH Liang, JM Hooker, ...
Molecular pharmaceutics 11 (11), 3832-3838, 2014
122014
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