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Morgan DeSantis
Morgan DeSantis
Verified email at umich.edu
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Cited by
Cited by
Year
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
4472018
Mechanism and regulation of cytoplasmic dynein
MA Cianfrocco, ME DeSantis, AE Leschziner, SL Reck-Peterson
Annual review of cell and developmental biology 31 (1), 83-108, 2015
2642015
Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events
ME Jackrel, ME DeSantis, BA Martinez, LM Castellano, RM Stewart, ...
Cell 156 (1), 170-182, 2014
2522014
Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients
ME DeSantis, EH Leung, EA Sweeny, ME Jackrel, M Cushman-Nick, ...
Cell 151 (4), 778-793, 2012
2002012
The human cytoplasmic dynein interactome reveals novel activators of motility
WB Redwine, ME DeSantis, I Hollyer, ZM Htet, PT Tran, SK Swanson, ...
Elife 6, e28257, 2017
1422017
Fission yeast does not age under favorable conditions, but does so after stress
M Coelho, A Dereli, A Haese, S Kühn, L Malinovska, ME DeSantis, ...
Current Biology 23 (19), 1844-1852, 2013
1242013
The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation
EA Sweeny, ME Jackrel, MS Go, MA Sochor, BM Razzo, ME DeSantis, ...
Molecular cell 57 (5), 836-849, 2015
1062015
LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes
ZM Htet, JP Gillies, RW Baker, AE Leschziner, ME DeSantis, ...
Nature cell biology 22 (5), 518-525, 2020
942020
Lis1 has two opposing modes of regulating cytoplasmic dynein
ME DeSantis, MA Cianfrocco, ZM Htet, PT Tran, SL Reck-Peterson, ...
Cell 170 (6), 1197-1208. e12, 2017
932017
The elusive middle domain of Hsp104 and ClpB: location and function
ME DeSantis, J Shorter
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 29-39, 2012
922012
Self-repair protects microtubules from destruction by molecular motors
S Triclin, D Inoue, J Gaillard, ZM Htet, ME DeSantis, D Portran, E Derivery, ...
Nature Materials 20 (6), 883-891, 2021
752021
Hsp104 drives “protein-only” positive selection of Sup35 prion strains encoding strong [PSI+]
ME DeSantis, J Shorter
Chemistry & biology 19 (11), 1400-1410, 2012
572012
Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation
ME DeSantis, EA Sweeny, D Snead, EH Leung, MS Go, K Gupta, ...
Journal of Biological Chemistry 289 (2), 848-867, 2014
552014
Association energetics of cross-reactive and specific antibodies
S Mohan, K Kourentzi, KA Schick, C Uehara, CA Lipschultz, M Acchione, ...
Biochemistry 48 (6), 1390-1398, 2009
332009
Purification of hsp104, a protein disaggregase
EA Sweeny, ME DeSantis, J Shorter
Journal of visualized experiments: JoVE, 2011
302011
Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies
M Acchione, CA Lipschultz, ME DeSantis, A Shanmuganathan, M Li, ...
Molecular immunology 47 (2-3), 457-464, 2009
272009
The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor
R Agrawal, JP Gillies, JL Zang, J Zhang, SR Garrott, H Shibuya, ...
Elife 11, e78201, 2022
242022
Structures of human dynein in complex with the lissencephaly 1 protein, LIS1
JM Reimer, ME DeSantis, SL Reck-Peterson, AE Leschziner
Elife 12, e84302, 2023
172023
Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity
S He, JP Gillies, JL Zang, CM Córdoba-Beldad, I Yamamoto, Y Fujiwara, ...
Nature communications 14 (1), 1715, 2023
142023
Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics
M Acchione, YC Lee, ME DeSantis, CA Lipschultz, A Wlodawer, M Li, ...
Biochemistry 51 (30), 6017-6027, 2012
142012
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