A DNA vector-based RNAi technology to suppress gene expression in mammalian cells G Sui, C Soohoo, EB Affar, F Gay, Y Shi, WC Forrester, Y Shi Proceedings of the National Academy of Sciences 99 (8), 5515-5520, 2002 | 2104 | 2002 |
Coordinated histone modifications mediated by a CtBP co-repressor complex Y Shi, J Sawada, G Sui, EB Affar, JR Whetstine, F Lan, H Ogawa, ... Nature 422 (6933), 735-738, 2003 | 885 | 2003 |
Cleavage of automodified poly (ADP-ribose) polymerase during apoptosis: evidence for involvement of caspase-7 M Germain, EB Affar, D D'Amours, VM Dixit, GS Salvesen, GG Poirier Journal of Biological Chemistry 274 (40), 28379-28384, 1999 | 571 | 1999 |
Yin Yang 1 is a negative regulator of p53 G Sui, EB Affar, Y Shi, C Brignone, NR Wall, P Yin, M Donohoe, MP Luke, ... Cell 117 (7), 859-872, 2004 | 478 | 2004 |
Importance of poly (ADP-ribose) glycohydrolase in the control of poly (ADP-ribose) metabolism L Davidovic, M Vodenicharov, EB Affar, GG Poirier Experimental cell research 268 (1), 7-13, 2001 | 447 | 2001 |
BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation A Bononi, C Giorgi, S Patergnani, D Larson, K Verbruggen, M Tanji, ... Nature 546 (7659), 549-553, 2017 | 424 | 2017 |
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair H Yu, H Pak, I Hammond-Martel, M Ghram, A Rodrigue, S Daou, ... Proceedings of the National Academy of Sciences 111 (1), 285-290, 2014 | 416 | 2014 |
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression H Yu, N Mashtalir, S Daou, I Hammond-Martel, J Ross, G Sui, GW Hart, ... Molecular and cellular biology 30 (21), 5071-5085, 2010 | 335 | 2010 |
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis H Ding, DS Schwarz, A Keene, EB Affar, L Fenton, X Xia, Y Shi, ... Aging cell 2 (4), 209-217, 2003 | 214 | 2003 |
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression EB Affar, F Gay, Y Shi, H Liu, M Huarte, S Wu, T Collins, E Li, Y Shi Molecular and cellular biology, 2006 | 203 | 2006 |
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O N Mashtalir, S Daou, H Barbour, NN Sen, J Gagnon, I Hammond-Martel, ... Molecular cell 54 (3), 392-406, 2014 | 198 | 2014 |
Par-4 links dopamine signaling and depression SK Park, MD Nguyen, A Fischer, MPS Luke, EB Affar, PB Dieffenbach, ... Cell 122 (2), 275-287, 2005 | 197 | 2005 |
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer*♦ S Daou, I Hammond-Martel, N Mashtalir, H Barbour, J Gagnon, ... Journal of Biological Chemistry 290 (48), 28643-28663, 2015 | 149 | 2015 |
Caspase-3-mediated processing of poly (ADP-ribose) glycohydrolase during apoptosis EB Affar, M Germain, E Winstall, M Vodenicharov, RG Shah, GS Salvesen, ... Journal of Biological Chemistry 276 (4), 2935-2942, 2001 | 149 | 2001 |
Roles of ubiquitin signaling in transcription regulation I Hammond-Martel, H Yu, EB Affar Cellular signalling 24 (2), 410-421, 2012 | 130 | 2012 |
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90 A Orthwein, AM Patenaude, EB Affar, A Lamarre, JC Young, JM Di Noia Journal of Experimental Medicine 207 (12), 2751-2765, 2010 | 128 | 2010 |
Roles and mechanisms of BAP1 deubiquitinase in tumor suppression L Masclef, O Ahmed, B Estavoyer, B Larrivée, N Labrecque, A Nijnik, ... Cell Death & Differentiation 28 (2), 606-625, 2021 | 122 | 2021 |
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway S Daou, N Mashtalir, I Hammond-Martel, H Pak, H Yu, G Sui, JL Vogel, ... Proceedings of the National Academy of Sciences 108 (7), 2747-2752, 2011 | 117 | 2011 |
ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells Y Auclair, R Rouget, EB Affar, EA Drobetsky Proceedings of the National Academy of Sciences 105 (46), 17896-17901, 2008 | 115 | 2008 |
Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes H Barbour, S Daou, M Hendzel, EB Affar Nature communications 11 (1), 5947, 2020 | 107 | 2020 |