| A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response B Adamson, A Smogorzewska, FD Sigoillot, RW King, SJ Elledge Nature cell biology 14 (3), 318-328, 2012 | 495 | 2012 |
| Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage X Zeng, F Sigoillot, S Gaur, S Choi, KL Pfaff, DC Oh, N Hathaway, ... Cancer cell 18 (4), 382-395, 2010 | 354 | 2010 |
| Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C KL Sackton, N Dimova, X Zeng, W Tian, M Zhang, TB Sackton, J Meaders, ... Nature 514 (7524), 646-649, 2014 | 253 | 2014 |
| A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens FD Sigoillot, S Lyman, JF Huckins, B Adamson, E Chung, B Quattrochi, ... Nature methods 9 (4), 363-366, 2012 | 200 | 2012 |
| YAP, but not RSPO-LGR4/5, signaling in biliary epithelial cells promotes a ductular reaction in response to liver injury L Planas-Paz, T Sun, M Pikiolek, NR Cochran, S Bergling, V Orsini, ... Cell stem cell 25 (1), 39-53. e10, 2019 | 194 | 2019 |
| Vigilance and validation: Keys to success in RNAi screening FD Sigoillot, RW King ACS chemical biology 6 (1), 47-60, 2011 | 169 | 2011 |
| USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin L Ji, B Lu, R Zamponi, O Charlat, R Aversa, Z Yang, F Sigoillot, X Zhu, ... Nature communications 10 (1), 4184, 2019 | 111 | 2019 |
| Cell cycle-dependent regulation of pyrimidine biosynthesis FD Sigoillot, JA Berkowski, SM Sigoillot, DH Kotsis, HI Guy Journal of Biological Chemistry 278 (5), 3403-3409, 2003 | 102 | 2003 |
| CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma NT Ross, F Lohmann, S Carbonneau, A Fazal, WA Weihofen, S Gleim, ... Nature chemical biology 16 (1), 50-59, 2020 | 78 | 2020 |
| Discovery of a ZIP7 inhibitor from a Notch pathway screen E Nolin, S Gans, L Llamas, S Bandyopadhyay, SM Brittain, ... Nature chemical biology 15 (2), 179-188, 2019 | 67 | 2019 |
| Hyperactivation of MAPK signaling is deleterious to RAS/RAF-mutant melanoma GP Leung, T Feng, FD Sigoillot, FC Geyer, MD Shirley, DA Ruddy, ... Molecular Cancer Research 17 (1), 199-211, 2019 | 63 | 2019 |
| Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades FD Sigoillot, DR Evans, HI Guy Journal of Biological Chemistry 277 (18), 15745-15751, 2002 | 60 | 2002 |
| A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production A Hyrina, C Jones, D Chen, S Clarkson, N Cochran, P Feucht, G Hoffman, ... Cell Reports 29 (10), 2970-2978. e6, 2019 | 58 | 2019 |
| The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20 HJ Lim, NV Dimova, MKM Tan, FD Sigoillot, RW King, Y Shi Molecular and cellular biology 33 (21), 4166-4180, 2013 | 57 | 2013 |
| Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells FD Sigoillot, SM Sigoillot, HI Guy International journal of cancer 109 (4), 491-498, 2004 | 56 | 2004 |
| Nuclear Localization and Mitogen-Activated Protein Kinase Phosphorylationof the Multifunctional ProteinCAD FD Sigoillot, DH Kotsis, V Serre, SM Sigoillot, DR Evans, HI Guy Journal of Biological Chemistry 280 (27), 25611-25620, 2005 | 54 | 2005 |
| Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis B Yilmazel, Y Hu, F Sigoillot, JA Smith, CE Shamu, N Perrimon, SE Mohr BMC bioinformatics 15, 1-6, 2014 | 52 | 2014 |
| Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC H Zeng, J Castillo-Cabrera, M Manser, B Lu, Z Yang, V Strande, D Begue, ... Elife 8, e50223, 2019 | 43 | 2019 |
| DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic-and acquired-degrader resistance M Schröder, M Renatus, X Liang, F Meili, T Zoller, S Ferrand, F Gauter, ... Nature communications 15 (1), 275, 2024 | 38 | 2024 |
| MiR-210 promotes sensory hair cell formation in the organ of corti S Riccardi, S Bergling, F Sigoillot, M Beibel, A Werner, J Leighton-Davies, ... BMC genomics 17, 1-14, 2016 | 33 | 2016 |
Jeremy F. HuckinsVP of R&D at Biocogniv Inc.Verified email at biocogniv.com
