The Lkb1 metabolic sensor maintains haematopoietic stem cell survival S Gurumurthy, SZ Xie, B Alagesan, J Kim, RZ Yusuf, B Saez, A Tzatsos, ... Nature 468 (7324), 659-663, 2010 | 439 | 2010 |
Diabetes impairs hematopoietic stem cell mobilization by altering niche function F Ferraro, S Lymperi, S Méndez-Ferrer, B Saez, JA Spencer, BY Yeap, ... Science translational medicine 3 (104), 104ra101-104ra101, 2011 | 347 | 2011 |
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias SM Sykes, SW Lane, L Bullinger, D Kalaitzidis, R Yusuf, B Saez, F Ferraro, ... Cell 146 (5), 697-708, 2011 | 299 | 2011 |
Epigenetic memory underlies cell-autonomous heterogeneous behavior of hematopoietic stem cells WC Vionnie, RZ Yusuf, T Oki, J Wu, B Saez, X Wang, C Cook, ... Cell 167 (5), 1310-1322. e17, 2016 | 277 | 2016 |
Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth X Agirre, A Jiménez-Velasco, E San José-Enériz, L Garate, E Bandrés, ... Molecular cancer research 6 (12), 1830-1840, 2008 | 272 | 2008 |
Functions of replication protein A as a sensor of R loops and a regulator of RNaseH1 HD Nguyen, T Yadav, S Giri, B Saez, TA Graubert, L Zou Molecular cell 65 (5), 832-847. e4, 2017 | 257 | 2017 |
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β‐catenin P Simic, K Zainabadi, E Bell, DB Sykes, B Saez, S Lotinun, R Baron, ... EMBO molecular medicine 5 (3), 430-440, 2013 | 254 | 2013 |
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin R Palchaudhuri, B Saez, J Hoggatt, A Schajnovitz, DB Sykes, TA Tate, ... Nature biotechnology 34 (7), 738-745, 2016 | 223 | 2016 |
Myocardial infarction activates CCR2+ hematopoietic stem and progenitor cells P Dutta, HB Sager, KR Stengel, K Naxerova, G Courties, B Saez, ... Cell stem cell 16 (5), 477-487, 2015 | 213 | 2015 |
Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations A Pardo-Saganta, BM Law, PR Tata, J Villoria, B Saez, H Mou, R Zhao, ... Cell stem cell 16 (2), 184-197, 2015 | 212 | 2015 |
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation AU Steinbicker, C Sachidanandan, AJ Vonner, RZ Yusuf, DY Deng, ... Blood, The Journal of the American Society of Hematology 117 (18), 4915-4923, 2011 | 204 | 2011 |
Parent stem cells can serve as niches for their daughter cells A Pardo-Saganta, PR Tata, BM Law, B Saez, RDW Chow, M Prabhu, ... Nature 523 (7562), 597-601, 2015 | 177 | 2015 |
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation A Czechowicz, R Palchaudhuri, A Scheck, YU Hu, J Hoggatt, B Saez, ... Nature communications 10 (1), 617, 2019 | 153 | 2019 |
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia H Zhang, M Alberich-Jorda, G Amabile, H Yang, PB Staber, A Di Ruscio, ... Cancer cell 24 (5), 575-588, 2013 | 141 | 2013 |
Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow VWC Yu, B Saez, C Cook, S Lotinun, A Pardo-Saganta, YH Wang, ... Journal of Experimental Medicine 212 (5), 759-774, 2015 | 137 | 2015 |
Splicing factor gene mutations in hematologic malignancies B Saez, MJ Walter, TA Graubert Blood, The Journal of the American Society of Hematology 129 (10), 1260-1269, 2017 | 127 | 2017 |
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome CL Shirai, BS White, M Tripathi, R Tapia, JN Ley, M Ndonwi, S Kim, ... Nature communications 8 (1), 14060, 2017 | 125 | 2017 |
Identification of overexpressed genes in frequently gained/amplified chromosome regions in multiple myeloma C Largo, S Alvarez, B Saez, D Blesa, JI Martin-Subero, I González-García, ... Haematologica 91 (2), 184-191, 2006 | 88 | 2006 |
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway S Ramasamy, B Saez, S Mukhopadhyay, D Ding, AM Ahmed, X Chen, ... Proceedings of the National Academy of Sciences 113 (7), 1871-1876, 2016 | 80 | 2016 |
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers RZ Yusuf, B Saez, A Sharda, N Van Gastel, VWC Yu, N Baryawno, ... Blood, The Journal of the American Society of Hematology 136 (11), 1303-1316, 2020 | 79 | 2020 |