Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities S Heinz, C Benner, N Spann, E Bertolino, YC Lin, P Laslo, JX Cheng, ... Molecular cell 38 (4), 576-589, 2010 | 12297 | 2010 |
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets Y Zhou, B Zhou, L Pache, M Chang, AH Khodabakhshi, O Tanaseichuk, ... Nature communications 10 (1), 1523, 2019 | 10507 | 2019 |
The selection and function of cell type-specific enhancers S Heinz, CE Romanoski, C Benner, CK Glass Nature reviews Molecular cell biology 16 (3), 144-154, 2015 | 1054 | 2015 |
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA D Wang, I Garcia-Bassets, C Benner, W Li, X Su, Y Zhou, J Qiu, W Liu, ... Nature 474 (7351), 390-394, 2011 | 962 | 2011 |
Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis T Kisseleva, M Cong, YH Paik, D Scholten, C Jiang, C Benner, K Iwaisako, ... Proceedings of the National Academy of Sciences 109 (24), 9448-9453, 2012 | 892 | 2012 |
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors S Ogawa, J Lozach, C Benner, G Pascual, RK Tangirala, S Westin, ... Cell 122 (5), 707-721, 2005 | 796 | 2005 |
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 777 | 2020 |
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ... Molecular cell 51 (3), 310-325, 2013 | 724 | 2013 |
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription MTY Lam, H Cho, HP Lesch, D Gosselin, S Heinz, Y Tanaka-Oishi, ... Nature 498 (7455), 511-515, 2013 | 602 | 2013 |
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones AL Hevener, JM Olefsky, D Reichart, MTA Nguyen, G Bandyopadyhay, ... The Journal of clinical investigation 117 (6), 1658-1669, 2007 | 572 | 2007 |
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate YC Lin, S Jhunjhunwala, C Benner, S Heinz, E Welinder, R Mansson, ... Nature immunology 11 (7), 635-643, 2010 | 555 | 2010 |
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity S Shalapour, XJ Lin, IN Bastian, J Brain, AD Burt, AA Aksenov, ... Nature 551 (7680), 340-345, 2017 | 525 | 2017 |
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression W Liu, B Tanasa, OV Tyurina, TY Zhou, R Gassmann, WT Liu, KA Ohgi, ... Nature 466 (7305), 508-512, 2010 | 462 | 2010 |
Transcription elongation can affect genome 3D structure S Heinz, L Texari, MGB Hayes, M Urbanowski, MW Chang, N Givarkes, ... Cell 174 (6), 1522-1536. e22, 2018 | 417 | 2018 |
Effect of natural genetic variation on enhancer selection and function S Heinz, CE Romanoski, C Benner, KA Allison, MU Kaikkonen, ... Nature 503 (7477), 487-492, 2013 | 362 | 2013 |
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors A Crotti, C Benner, BE Kerman, D Gosselin, C Lagier-Tourenne, ... Nature neuroscience 17 (4), 513-521, 2014 | 342 | 2014 |
The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression C Benner, T van der Meulen, E Cacéres, K Tigyi, CJ Donaldson, ... BMC genomics 15, 1-17, 2014 | 325 | 2014 |
Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate YC Lin, C Benner, R Mansson, S Heinz, K Miyazaki, M Miyazaki, ... Nature immunology 13 (12), 1196-1204, 2012 | 306 | 2012 |
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways S Ghisletti, W Huang, K Jepsen, C Benner, G Hardiman, MG Rosenfeld, ... Genes & development 23 (6), 681-693, 2009 | 297 | 2009 |
Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response GD Barish, TY Ruth, M Karunasiri, CB Ocampo, J Dixon, C Benner, ... Genes & development 24 (24), 2760-2765, 2010 | 296 | 2010 |