עקוב אחר
David Solit
David Solit
Director, Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center
כתובת אימייל מאומתת בדומיין mskcc.org - דף הבית
כותרת
צוטט על ידי
צוטט על ידי
שנה
Comprehensive molecular characterization of human colon and rectal cancer‏
Cancer Genome Atlas Network‏
Nature 487 (7407), 330, 2012‏
73822012
Tumor mutational load predicts survival after immunotherapy across multiple cancer types‏
RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ...‏
Nature genetics 51 (2), 202-206, 2019‏
30682019
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt‏
KE O'Reilly, F Rojo, QB She, D Solit, GB Mills, D Smith, H Lane, ...‏
Cancer research 66 (3), 1500-1508, 2006‏
29772006
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients‏
A Zehir, R Benayed, RH Shah, A Syed, S Middha, HR Kim, P Srinivasan, ...‏
Nature medicine 23 (6), 703-713, 2017‏
29132017
Comprehensive molecular characterization of urothelial bladder carcinoma‏
Cancer Genome Atlas Research Network‏
Nature 507 (7492), 315, 2014‏
25932014
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer‏
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...‏
Nature 486 (7404), 532-536, 2012‏
20162012
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion‏
R Straussman, T Morikawa, K Shee, M Barzily-Rokni, ZR Qian, J Du, ...‏
Nature 487 (7408), 500-504, 2012‏
19462012
OncoKB: a precision oncology knowledge base‏
D Chakravarty, J Gao, S Phillips, R Kundra, H Zhang, J Wang, ...‏
JCO precision oncology 1, 1-16, 2017‏
19322017
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)‏
PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ...‏
Nature 480 (7377), 387-390, 2011‏
16262011
Inherited DNA-repair gene mutations in men with metastatic prostate cancer‏
CC Pritchard, J Mateo, MF Walsh, N De Sarkar, W Abida, H Beltran, ...‏
New England Journal of Medicine 375 (5), 443-453, 2016‏
15602016
BRAF mutation predicts sensitivity to MEK inhibition‏
DB Solit, LA Garraway, CA Pratilas, A Sawai, G Getz, A Basso, Q Ye, ...‏
Nature 439 (7074), 358-362, 2006‏
15352006
AACR Project GENIE: powering precision medicine through an international consortium‏
AACR Project Genie Consortium, AACR Project GENIE Consortium, ...‏
Cancer discovery 7 (8), 818-831, 2017‏
12322017
Molecular determinants of response to anti–programmed cell death (PD)-1 and anti–programmed death-ligand 1 (PD-L1) blockade in patients with non–small-cell lung cancer profiled …‏
H Rizvi, F Sanchez-Vega, K La, W Chatila, P Jonsson, D Halpenny, ...‏
Journal of clinical oncology 36 (7), 633, 2018‏
12252018
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy‏
D Chowell, LGT Morris, CM Grigg, JK Weber, RM Samstein, V Makarov, ...‏
Science 359 (6375), 582-587, 2018‏
9952018
The genomic landscape of endocrine-resistant advanced breast cancers‏
P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross, N Vasan, Y Cai, ...‏
Cancer cell 34 (3), 427-438. e6, 2018‏
7972018
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function‏
AD Basso, DB Solit, G Chiosis, B Giri, P Tsichlis, N Rosen‏
Journal of Biological Chemistry 277 (42), 39858-39866, 2002‏
7782002
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity‏
MT Chang, S Asthana, SP Gao, BH Lee, JS Chapman, C Kandoth, JJ Gao, ...‏
Nature biotechnology 34 (2), 155-163, 2016‏
7462016
Genome sequencing identifies a basis for everolimus sensitivity‏
G Iyer, AJ Hanrahan, MI Milowsky, H Al-Ahmadie, SN Scott, ...‏
Science 338 (6104), 221-221, 2012‏
7182012
Clinical sequencing defines the genomic landscape of metastatic colorectal cancer‏
R Yaeger, WK Chatila, MD Lipsyc, JF Hechtman, A Cercek, ...‏
Cancer cell 33 (1), 125-136. e3, 2018‏
6762018
HER kinase inhibition in patients with HER2-and HER3-mutant cancers‏
DM Hyman, SA Piha-Paul, H Won, J Rodon, C Saura, GI Shapiro, D Juric, ...‏
Nature 554 (7691), 189-194, 2018‏
6732018
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מאמרים 1–20