Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9 R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ... Cell 170 (5), 899-912. e10, 2017 | 284 | 2017 |
A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells Y Diao, R Fang, B Li, Z Meng, J Yu, Y Qiu, KC Lin, H Huang, T Liu, ... Nature methods 14 (6), 629-635, 2017 | 263 | 2017 |
TET‐catalyzed oxidation of intragenic 5‐methylcytosine regulates CTCF‐dependent alternative splicing RJ Marina, D Sturgill, MA Bailly, M Thenoz, G Varma, MF Prigge, ... The EMBO journal 35 (3), 335-355, 2016 | 106 | 2016 |
Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes KW Brannan, IA Chaim, RJ Marina, BA Yee, ER Kofman, DA Lorenz, ... Nature methods 18 (5), 507-519, 2021 | 85 | 2021 |
An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models KH Morelli, Q Wu, ML Gosztyla, H Liu, M Yao, C Zhang, J Chen, ... Nature neuroscience 26 (1), 27-38, 2023 | 36 | 2023 |
Evaluation of engineered CRISPR-Cas-mediated systems for site-specific RNA editing RJ Marina, KW Brannan, KD Dong, BA Yee, GW Yeo Cell reports 33 (5), 2020 | 29 | 2020 |
Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9 E Yeo, K Brannan, R Marina, D Nelles US Patent 11,453,891, 2022 | 21 | 2022 |
Epigenomics meets splicing through the TETs and CTCF RJ Marina, S Oberdoerffer Cell Cycle 15 (11), 1397-1399, 2016 | 15 | 2016 |
Diabetic Insult–Induced Redistribution of MicroRNA in Spatially Organized Mitochondria in Cardiac Muscle RJ Marina, XD Fu Circulation: Cardiovascular Genetics 8 (6), 747-748, 2015 | 5 | 2015 |
RNA-Targeting CRISPR/Cas13d system eliminates disease-related phenotypes in pre-clinical models of huntington’s disease KH Morelli, Q Wu, ML Gosztyla, H Liu, C Zhang, J Chen, R Marina, K Lee, ... Biorxiv, 2022.01. 23.477417, 2022 | 1 | 2022 |
Automated, miniaturized, and scalable screening of healthcare workers, first responders, and students for SARS-CoV-2 in San Diego County SC Morgan, S Aigner, C Anderson, P Belda-Ferre, P De Hoff, CA Marotz, ... medRxiv, 2021.06. 25.21257885, 2021 | 1 | 2021 |
Methods and use of chimeric proteins E Yeo, KW Brannan, R Marina, IA Chaim, DA Lorenz US Patent App. 17/910,967, 2023 | | 2023 |
Directed editing of cellular rna via nuclear delivery of crispr/cas9 E Yeo, K Brannan, R Marina, D Nelles US Patent App. 17/811,626, 2023 | | 2023 |
Engineering RNA Base-editing Tools and Uncovering Post-transcriptional Regulatory Roles of RNA-binding Proteins in Neurodegeneration RJ Marina | | 2022 |